Inhibitory effects of endotoxin on LH secretion in the ovariectomized monkey are prevented by naloxone but not by an interleukin-1 receptor antagonist

NeuroImmunoModulation

Volumn 7, Issue 1, 2000, Pages 6-15

  Xiao, Ennian ^a   Xia Zhang, Linna ^a   Ferin, Michel ^a,b  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b NONE   (United States)

Author keywords

Endotoxin; Gonadotropins; Interleukin 1; Interleukin 1 receptor antagonist; LH; Monkey; Naloxone; Opiates; Stress

Indexed keywords

ENDOTOXIN; HYDROCORTISONE; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1ALPHA; LUTEINIZING HORMONE; NALOXONE; OPIATE PEPTIDE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; HYDROCORTISONE BLOOD LEVEL; HYDROCORTISONE RELEASE; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; LUTEINIZING HORMONE BLOOD LEVEL; LUTEINIZING HORMONE RELEASE; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; RHESUS MONKEY;

EID: 1642588146     PISSN: 10217401     EISSN: None     Source Type: Journal    
DOI: 10.1159/000026415     Document Type: Article

References (43)

1. Coleman ES, Elsasser TH, Kemppainen RJ, Coleman DA, Sartin JL: Effect of endotoxin on pituitary hormone secretion in sheep. Neuroendocrinology 1993;58:111-122.
2. Kujjo LL, Bosu WT, Perez GI: Opioid peptides involvement in endotoxin-induced suppression of LH secretion in ovariectomized Holstein heifers. Reprod Toxicol 1995;9:169-174.
3. Lenczowski MJ, Van Dam AM, Poole S, Larrick JW, Tilders DFJ: Role of circulating endotoxin and interleukin-6 in the ACTH and corticosterone response to intraperitoneal LPS. Am J Physiol 1997;273:R1870-R1877.
4. Battaglia DF, Bowen JM, Krasa HB, Thrun LA, Viguie C, Karsch FJ: Endotoxin inhibits the reproductive neuroendocrine axis while stimulating adrenal steroids: A simultaneous view from hypophyseal portal and peripheral blood. Endocrinology 1997;138:4273-4281.
5. Tilders FJ, DeRijk RH, Van Dam AM, Vincent VA, Schotanus K, Persoons JHA: Activation of the hypothalamus-pituitary-adrenal axis by bacterial endotoxins: Routes and intermediate signals. Psychoneuroendocrinology 1994;19:209-232.
6. Schobitz B, De Kloet ER, Holsboer F: Gene expression and function of interleukin 1, interleukin 6 and tumor necrosis factor in the brain. Prog Neurobiol 1994;44:397-432.
7. Benveniste EN, Benos DJ: TNF-alpha- and IFN-gamma-mediated signal transduction pathways: Effects on glial cell gene expression and function. FASEB J 1995;9:1577-1584.
8. Hopkins SJ, Rothwell NJ: Cytokines and the nervous system. I. Expression and recognition. Trends Neurosci 1995;18:83-88.
9. De Simoni MG, Terreni L, Chiesa R, Mangiarotti F, Forloni GL: Interferon-gamma potentiates interleukin (IL)-6 and tumor necrosis factor-alpha but not IL-1beta induced by endotoxin in the brain. Endocrinology 1997;138:5220-5226.
10. Gottschall PE, Komaki G, Arimura A: Increased circulating interleukin-1 and interleukin-6 after intracerebroventricular injection of lipopolysaccharide. Neuroendocrinology 1992; 56:935-938.
11. Muramami N, Fukata J, Tsukada T, Kobayashi H, Ebisui O, Segawah H, Muro S, Imura H, Nakao K: Bacterial lipopolysaccharide-induced expression of interleukin-6 messenger ribonucleic acid in the rat hypothalamus, pituitary, adrenal gland, and spleen. Endocrinology 1993;133:2574-2578.
12. De Simoni MG, Del Bo R, De Luigi A, Simard S, Forloni G: Central endotoxin induces different patterns of interleukin (IL)-I beta and IL-6 messenger ribonucleic acid expression and IL-6 secretion in the brain and periphery. Endocrinology 1995;136:897-902.
13. Laye S, Parnet P, Goujon E, Dantzer R: Peripheral administration of lipopolysaccharide induces the expression of cytokine transcripts in the brain and pituitary of mice. Brain Res Mol Brain Res 1994;27:157-162.
14. Gabellec MM, Griffais R, Fillion G, Haour F: Expression of interleukin 1 alpha, interleukin 1 beta and interleukin 1 receptor antagonist mRNA in mouse brain: Regulation by bacterial lipopolysaccharide (LPS) treatment. Brain Res Mol Brain Res 1995;31:122-130.
15. Loddick SA, Wong ML, Bongiorno PB, Gold PW, Licinio J, Rothwell NJ: Endogenous interleukin-1 receptor antagonist is neuroprotective. Biochem Biophys Res Commun 1997; 234:211-215.
16. Ebisui O, Fukata J, Murakami N, Kobayashi H, Segawa H, Muro S, Hanaoka I, Naito Y, Masui Y, Ohmoto Y, Imura H, Nakao K: Effect of IL-1 receptor antagonist and antiserum to TNF-alpha on LPS-induced plasma ACTH and corticosterone rise in rats. Am J Physiol 1994;266:E986-E992.
17. Bonavera JJ, Kalra SP, Kalra PS: Mode of action of interleukin-1 in suppression of pituitary LH release in castrated male rats. Brain Res 1993;612:1-8.
18. Rivier C, Vale W: In the rat, interleukin-1α acts at the level of the brain and the gonads to interfere with gonadotropin and sex steroid secretion. Endocrinology 1989;124:2105-2109.
19. Feng YJ, Shalts E, Xia L, Rivier J, Rivier C, Vale W, Ferin M: An inhibitory effect of interleukin-1α on basal gonadotropin release in the ovariectomized rhesus monkey: Reversal by a corticotropin-releasing factor antagonist. Endocrinology 1991;128:2077-2082.
20. Xiao E, Xia-Zhang L, Thornell D, Shalts E, Ferin M: The luteinizing hormone but not the cortisol response to arginine vasopressin is prevented by naloxone and a corticotropin-releasing hormone antagonist in the ovariectomized rhesus monkey. Neuroendocrinology 1996;64: 225-232.
21. Xiao E, Xia-Zhang L, Barth A, Zhu J, Ferin M: Stress and the menstrual cycle: Relevance of cycle quality in the short- and long-term response to a 5-day endotoxin treatment during the follicular phase in the rhesus monkey. J Clin Endocrinol Metab 1998;83:2454-2460.
22. Kniss DA, Zimmerman PD, Garver CL, Fertel RH: Interleukin-1 receptor antagonist blocks interleukin-1-induced expression of cyclooxygenase-2 in endometrium. Am J Obstet Gynecol 1997;177:559-567.
23. Dinarello CA, Thompson RC: Blocking IL-1: Interleukin 1 receptor antagonist in vivo and in vitro. Immunol Today 1991;12:404-410.
24. Schotanus K, Tilders FJ, Berkenbosch F: Human recombinant interleukin-1 receptor antagonist prevents adrenocorticotropin, but not interleukin-6 responses to bacterial endotoxin in rats. Endocrinology 1993;133:2461-2468.
25. Ebisui O, Fukata J, Tominaga T, Muramaki N, Kobayashi H, Segawa H, Muro S, Naito Y, Nakai Y, Masui Y, Nishida T, Imura H: Roles of interleukin-1 alpha and -I beta in endotoxin-induced suppression of plasma gonadotropin levels in rats. Endocrinology 1992;130:3307-3313.
26. Luheshi G, Miller AJ, Brouwer S, Dascombe MJ, Rothwell NJ, Hopkins SJ: Interleukin-1 receptor antagonist inhibits endotoxin fever and systemic interleukin-6 induction in the rat. Am J Physiol 1996;270:E91-E95.
27. Lenczowski MJ, Van Dam AM, Poole S, Larrick JW, Tilders FJ: Role of circulating endotoxin and interleukin-6 in the ACTH and corticosterone response to intraperitoneal LPS. Am J Physiol 1997;273:R1870-R1877.
28. Spangelo BL, Judd AM, Isakson PC, MacLeod RM: Interleukin-1 stimulates interleukin-6 release from rat anterior pituitary cells in vitro. Endocrinology 1991;128:2685-2692.
29. Spangelo BL, Judd AM, MacLeod RM, Goodman DW, Isakson PC: Endotoxin-induced release of interleukin-6 from rat medial basal hypothalami. Endocrinology 1990;127:1779-1785.
30. Givalois L, Dornand J, Mekaouche M, Solier MD, Bristow AF, Ixart G, Siaud P, Assanmacher I, Barbanel G: Temporal cascade of plasma level surges in ACTH, corticosterone, and cytokines in endotoxin-challenged rats. Am J Physiol 1994;267:R164-R170.
31. Lyson K, McCann SM: The effect of interleukin-6 on pituitary hormone release in vivo and in vitro. Neuroendocrinology 1991;54:262-266.
32. Spath-Schwalbe E, Schrezenmeier H, Bornstein S, Burger K, Porzsolt K, Born J: Endocrine effects of recombinant interleukin-6 in man. Neuroendocrinology 1996;63:237-243.
33. Turnbull AV, Rivier C: Regulation of the HPA axis by cytokines. Brain Behav Immun 1995;9: 253-275.
34. Turnbull AU, Rivier CL: Intracerebroventricular passive immunization. I. The effect of intracerebroventricular administration of an antiserum to tumor necrosis factor-α on the plasma ACTU response to lipopolysaccharide in rats. Endocrinology 1998;139:119-127.
35. Takemura T, Makino S, Takao T, Asaba K, Suemaru S, Hashimoto K: Hypothalamic-pituitary-adrenocortical responses to single vs. repeated endotoxin lipopolysaccharide administration in the rat. Brain Res 1997;767:181-191.
36. Shanks N, Meaney MJ: Hypothalamic-pituitary-adrenal activation following endotoxin administration in the developing rat: A CRH-mediated effect. J Neuroendocrinol 1994;6: 375-383.
37. Nappi RE, Bonneau MJ, Rivest S: Influence of the estrous cycle on c-fos and CRH gene transcription in the brain of endotoxin-challenged female rats. Neuroendocrinology 1997;65:29-46.
38. Kakucska I, Qi Y, Clark BD, Lechan RM: Endotoxin-induced corticotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus is mediated centrally by interlcukin-1. Endocrinology 1993;133: 815-821.
39. Herman JP: In situ hybridization analysis of vasopressin gene transcription in the paraventricular and supraoptic nuclei of the rat: Regulation by stress and glucocorticoids. J Comp Neurol 1995;363:15-27.
40. Gindoff PR, Ferin M: Endogenous opioid peptides modulate the effect of corticotropin-releasing factor on gonadotropin release in the primate. Endocrinology 1987;121:837-842.
41. Jackson RV, Grice JE, Jackson AJ, Hockings GI: Naloxone-induced ACTH release in man is inhibited by clonidine. Clin Exp Pharmacol Physiol 1990;17:179-184.
42. Tapp WN, Mittler JC, Natelson BH: Effects of naloxone on corticostcrone response to stress. Pharmacol Biochem Behav 1981;14:749-51.
43. Hockings GI, Grice JE, Walters MM, Crosbie GV, Torpy DJ, Jackson RV: A synergistic adrenocorticotropin response to naloxone and vasopressin in normal humans: Evidence that naloxone stimulates endogenous corticotropin-releasing hormone. Neuroendocrinology 1995; 61:198-206.