Oxidation of ryanodine receptor (RyR) and calmodulin enhance Ca release and pathologically alter, RyR structure and calmodulin affinity

Journal of Molecular and Cellular Cardiology

Volumn 85, Issue , 2015, Pages 240-248

  Oda, Tetsuro ^a,b   Yang, Yi ^a,c   Uchinoumi, Hitoshi ^a   Thomas, David D ^c   Chen Izu, Ye ^a   Kato, Takayoshi ^b   Yamamoto, Takeshi ^b   Yano, Masafumi ^b   Cornea, Razvan L ^c   Bers, Donald M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Calmodulin; Dantrolene; FKBP12.6; Reactive oxygen species; Ryanodine receptor

Indexed keywords

CALCIUM ION; CALMODULIN; DANTROLENE; FK 506 BINDING PROTEIN; HYDROGEN PEROXIDE; RYANODINE RECEPTOR 2; CALCIUM; PROTEIN BINDING; RYANODINE RECEPTOR; TACROLIMUS BINDING PROTEIN 1B;

ALLOSTERISM; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING KINETICS; BIOSENSOR; CALCIUM TRANSPORT; CHANNEL GATING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DOMAIN PEPTIDE BIOSENSOR; DOMAIN UNZIPPING; FLUORESCENCE; HEART FAILURE; HEART MUSCLE CELL; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; RAT; ANIMAL; CALCIUM SIGNALING; CARDIAC MUSCLE CELL; CELL CULTURE; KINETICS; METABOLISM; OXIDATION REDUCTION REACTION;

ANIMALS; CALCIUM; CALCIUM SIGNALING; CALMODULIN; CELLS, CULTURED; HYDROGEN PEROXIDE; KINETICS; MYOCYTES, CARDIAC; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEIN BINDING; PROTEIN CONFORMATION; RATS; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; TACROLIMUS BINDING PROTEINS;

EID: 84932650368     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2015.06.009     Document Type: Article

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