Hydrogen peroxide-mediated SERCA cysteine 674 oxidation contributes to impaired cardiac myocyte relaxation in senescent mouse heart.

Journal of the American Heart Association

Volumn 2, Issue 4, 2013, Pages

  Qin, Fuzhong ^a   Siwik, Deborah A ^b   Lancel, Steve ^b   Zhang, Jingmei ^b   Kuster, Gabriela M ^b   Luptak, Ivan ^b   Wang, Lei ^b   Tong, Xiaoyong ^b   Kang, Y James ^b   Cohen, Richard A ^b   Colucci, Wilson S ^b  

^a BOSTON UNIVERSITY MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CATALASE; CYSTEINE; ENZYME ACTIVATOR; HYDROGEN PEROXIDE; OXIDIZING AGENT; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE;

AGE; ANIMAL; CALCIUM SIGNALING; CELL AGING; CELL CULTURE; DRUG EFFECTS; ENZYME ACTIVATION; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; HEART CONTRACTION; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE; HEART MUSCLE CELL; HYPERTROPHY, LEFT VENTRICULAR; METABOLISM; MOUSE; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PREVENTION AND CONTROL; RAT; TRANSGENIC MOUSE; UPREGULATION;

AGE FACTORS; ANIMALS; CALCIUM SIGNALING; CATALASE; CELL AGING; CELLS, CULTURED; CYSTEINE; ENZYME ACTIVATION; ENZYME ACTIVATORS; HYDROGEN PEROXIDE; HYPERTROPHY, LEFT VENTRICULAR; MICE; MICE, TRANSGENIC; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOCYTES, CARDIAC; OXIDANTS; OXIDATION-REDUCTION; OXIDATIVE STRESS; RATS; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; TRANSFECTION; UP-REGULATION; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR FUNCTION, LEFT;

EID: 84898472703     PISSN: None     EISSN: 20479980     Source Type: Journal    
DOI: 10.1161/JAHA.113.000184     Document Type: Article

References (0)