Overexpression of FK506-binding protein FKBP12.6 in cardiomyocytes reduces ryanodine receptor-mediated Ca2+ leak from the sarcoplasmic reticulum and increases contractility

Circulation Research

Volumn 88, Issue 2, 2001, Pages 188-194

  Prestle, Juergen ^a   Janssen, Paul M L ^a   Janssen, Anita P ^a   Zeitz, Oliver ^a   Lehnart, Stephan E ^a   Bruce, Lorraine ^b   Smith, Godfrey L ^b   Hasenfuss, Gerd ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Adenovirus; Calcium; Cardiac myocytes; Gene transfer; Sarcoplasmic reticulum

Indexed keywords

BETA ESCIN; CAFFEINE; CALCIUM CHANNEL; CALCIUM ION; FK 506 BINDING PROTEIN; FURA 2; PROTEIN FKBP12; PROTEIN FKBP12.6; RECEPTOR SUBTYPE; RUTHENIUM; RYANODINE RECEPTOR; UNCLASSIFIED DRUG;

ADENOVIRUS; ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; EXCITATION CONTRACTION COUPLING; FEMALE; GENE OVEREXPRESSION; GENE TRANSFER; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN CONFORMATION; RABBIT; SARCOPLASMIC RETICULUM;

EID: 0035793341     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.88.2.188     Document Type: Article

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