FRET-based mapping of calmodulin bound to the RyR1 Ca 2+ release channel

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 15, 2009, Pages 6128-6133

  Cornea, Razvan L ^a   Nitu, Florentin ^a   Gruber, Simon ^a   Kohler, Katherine ^a   Satzer, Michael ^a   Thomas, David D ^a   Fruen, Bradley R ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Calcium; Excitation contraction coupling; FKBP; Fluorescence; Ryanodine receptor; Sarcoplasmic reticulum

Indexed keywords

CALCIUM; CALCIUM CHANNEL; CALMODULIN; FK 506 BINDING PROTEIN; RYANODINE RECEPTOR 1; RYANODINE RECEPTOR;

ARTICLE; BINDING SITE; CYTOPLASM; FLUORESCENCE RESONANCE ENERGY TRANSFER; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CRYOELECTRON MICROSCOPY; GENETICS; METABOLISM; PROTEIN TERTIARY STRUCTURE; SWINE; TIME;

ANIMALS; BINDING SITES; CALMODULIN; CRYOELECTRON MICROSCOPY; FLUORESCENCE RESONANCE ENERGY TRANSFER; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SWINE; TACROLIMUS BINDING PROTEINS; TIME FACTORS;

EID: 65549087493     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0813010106     Document Type: Article

References (27)

1. Bers DM (2004) Macromolecular complexes regulating cardiac ryanodine receptor function. J Mol Cell Cardiol 37:417-429.
2. Zalk R, Lehnart SE, Marks AR (2007) Modulation of the ryanodine receptor and intracellular calcium. Annu Rev Biochem 76:367-385.
3. Moore CP, et al. (1999) Apocalmodulin and Ca2- calmodulin bind to the same region on the skeletal muscle Ca2- release channel. Biochemistry 38:8532-8537.
4. Tripathy A, Xu L, Mann G, Meissner G (1995) Calmodulin activation and inhibition of skeletal muscle Ca2- release channel (ryanodine receptor). Biophys J 69:106-119.
5. Fruen BR, et al. (2003) Regulation of the RYR1 and RYR2 Ca2- release channel isoforms by Ca2--insensitive mutants of calmodulin. Biochemistry 42:2740-2747.
6. Wagenknecht T, et al. (1997) Locations of calmodulin and FK506-binding protein on the three-dimensional architecture of the skeletal muscle ryanodine receptor. J Biol Chem 272:32463-32471.
7. Samsó M, Wagenknecht T (2002) Apocalmodulin and Ca2--calmodulin bind to neighboring locations on the ryanodine receptor. J Biol Chem 277:1349-1353.
8. Samsó M, Wagenknecht T, Allen PD (2005) Internal structure and visualization of transmembrane domains of the RyR1 calcium release channel by cryo-EM. Nat Struct Mol Biol 12:539-544.
9. Samsó M, Shen X, Allen PD (2006) Structural characterization of the RyR1-FKBP12 Interaction. J Mol Biol 356:917-927.
10. Rodney GG, et al. (2001) Calcium binding to calmodulin leads to an N-terminal shift in its binding site on the ryanodine receptor. J Biol Chem 276:2069-2074.
11. Yamaguchi N, Xin C, Meissner G (2001) Identification of apocalmodulin and Ca2--cal-modulin regulatory domain in skeletal muscle Ca2- release channel, ryanodine receptor. J Biol Chem 276:22579-22585.
12. Maximciuc AA, Putkey JA, Shamoo Y, Mackenzie KR (2006) Complex of calmodulin with a ryanodine receptor target reveals a novel, flexible binding mode. Structure 14:1547-1556.
13. Zhang H, Zhang JZ, Danila CI, Hamilton SL (2003) A noncontiguous, intersubunit binding site for calmodulin on the skeletal muscle Ca2- release channel. J Biol Chem 278:8348-8355.
14. Yamaguchi N, Xu L, Evans KE, Pasek DA, Meissner G (2004) Different regions in skeletal and cardiac muscle ryanodine receptors are involved in transducing the functional effects of calmodulin. J Biol Chem 279:36433-36439.
15. Fruen BR, et al. (2005) Direct detection of calmodulin tuning by ryanodine receptor channel targets using a Ca2--sensitive acrylodan-labeled calmodulin. Biochemistry 44:278-284.
16. Barg S, Copello JA, Fleischer S (1997) Different interactions of cardiac and skeletal muscle ryanodine receptors with FK-506 binding protein isoforms. Am J Physiol 272:C1726-C1733.
17. Xin HB, Rogers K, Qi Y, Kanematsu T, Fleischer S (1999) Three amino acid residues determine selective binding of FK506-binding protein 12.6 to the cardiac ryanodine receptor. J Biol Chem 274:15315-15319.
18. Fruen BR, Bardy JM, Byrem TM, Strasburg GM, Louis CF (2000) Differential Ca2- sensitivity of skeletal and cardiac muscle ryanodine receptors in the presence of calmodulin. Am J Physiol 279:C724-C733.
19. Yin CC, D'Cruz LG, Lai FA (2008) Ryanodine receptor arrays: Not just a pretty pattern? Trends Cell Biol 18:149-156.
20. Serysheva II, et al. (2008) Subnanometer-resolution electron cryomicroscopy-based domain models for the cytoplasmic region of skeletal muscle RyR channel. Proc Natl Acad Sci USA 105:9610-9615.
21. Saimi Y, Kung C (1994) Ion channel regulation by calmodulin binding. FEBS Lett 350:155-158.
22. Tadross MR, Dick IE, Yue DT (2008) Mechanism of local and global Ca2- sensing by calmodulin in complex with a Ca2- channel. Cell 133:1228-1240.
23. Lai FA, Erickson HP, Rousseau E, Liu QY, Meissner G (1988) Purification and reconstitution of the calcium release channel from skeletal muscle. Nature 331:315-319.
24. Holzman TF, et al. (1991) Preliminary characterization of a cloned neutral isoelectric form of the human peptidyl prolyl isomerase cyclophilin. J Biol Chem 266:2474-2479.
25. Park ST, Aldape RA, Futer O, DeCenzo MT, Livingston DJ (1992) PPIase catalysis by human FK506-binding protein proceeds through a conformational twist mechanism. J Biol Chem 267:3316-3324.
26. Brooks SPJ, Storey KB (1992) Bound and determined: A computer program for making buffers of defined ion concentrations. Anal Biochem 201:119-126.
27. Haugland RP, Spence MTZ, Johnson ID, Basey A (2005) The Handbook: A Guide to Fluorescent Probes and Labeling Technologies (Molecular Probes, Eugene, OR).