Ethanol modulation of nicotinic acetylcho1ine receptor currents in cultured cortical neurons

Molecular Pharmacology

Volumn 55, Issue 1, 1999, Pages 39-49

  Aistrup, Gary L ^a   Marszalec, William ^a   Narahashi, Toshio ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; ACETYLCHOLINE; ALCOHOL; ALPHA BUNGAROTOXIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NICOTINIC RECEPTOR;

ANIMAL CELL; ARTICLE; BRAIN CELL; CONTROLLED STUDY; EMBRYO; MEMBRANE CURRENT; MODULATION; NERVE CELL CULTURE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT;

EID: 0032895274     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.55.1.39     Document Type: Article

References (36)

1. Blomqvist O, Ericson M, Engel JA and Soderpal MB (1997) Accumbal dopamine overflow after ethanol: Localization of the antagonizing effect of mecamylamine. Eur J Pharmacol 334:149-156.
2. Buisson B, Gopalakrishnan M, Arneric SP, Sullivan JP and Bertrand D (1996) Human α4β2 neuronal nicotinic acetylcholine receptor in HEK 293 cells: A patch-clamp study. J Neurosci 16:7880-7891.
3. Cardoso, RA, Valenzuela, CF, Chavez-Noriega, L, Harpold, M and Harris, RA (1998) Effects of ethanol on the function of neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes. Alcohol Clin Exp Res 22 (Suppl):46A.
4. Chavez-Noriega LE, Crona JH, Washburn MS, Urrutia A, Elliot KJ and Johnson, EC (1997) Pharmacological characterization of recombinant human neuronal nicotinic acetylcholine receptors hα2β2, hα2β4, hα3β2, hα3β4, hα4β2, hα4β4, and hα7 expressed in Xenopus oocytes. J Pharmacol Exp Ther 280:346-356.
5. Collins AC (1996) The Nicotinic Cholinergic Receptor as a Potential Site of Ethanol Action, in Pharmacological Effects of Ethanol on the Nervous System (Detrich RA and Erwin VG eds) pp 95-115, CRC Press, Boca Raton, FL.
6. Colquhoun LM and Patrick JW (1997) Pharmacology of neuronal nicotinic acetylcholine receptor subtypes. Adv Pharmacol 39:191-220.
7. Cooper ST and Millar NS (1997) Host cell-specific folding and assembly of the neuronal nicotinic acetylcholine receptor α7 subunit. J Neurochem 68:2140-2151.
8. Covernton PJO and Connolly JG (1997) Differential modulation of rat neuronal nicotinic receptor subtypes by acute application of ethanol. Br J Pharmacol 122: 1661-1668.
9. Crews FT, Morrow AL, Criswell H and Breese, G (1996) Effects of ethanol on ion channels. Int Rev Neurobiol 39:283-367.
10. Diamond I (1990) Models for the Investigation of Alcohol Withdrawal Seizures, in Alcohol and Seizures (Porter RJ, Mattson RH, Cramer JA and Diamond I eds) pp 25-28, F. A Davis Company, Philadelphia.
11. Diamond I and Gordon AS (1997) Cellular and molecular neuroscience of alcoholism. Physiol Rev 77:1-20.
12. Fenster CP, Rains MF, Noerager B, Quick MW and Lester AJ (1997) Influence of subunit composition on desensitization of neuronal acetylcholine receptors at low concentrations of nicotine. J Neurosci 17:5747-5759.
13. Flood P, Ramirez-Latorre J and Role L (1997) α4β2 neuronal nicotinic acetylcholine receptors in the central nervous system are inhibited by isoflurane and propofol, but α7-type nicotinic acetylcholine receptors are unaffected. Anesthesiology 86:859-865.
14. Freund RK and Palmer MR (1997) Ethanol depression of cerebellar Purkinje neuron firing involves nicotinic acetylcholine receptors. Exp Neurol 143:319-322.
15. Gopalakrishnan M, Buisson B, Touma E, Giordano T, Campbell JE, Hu IC, Donnelly-Roberts D, Arneric SP, Bertrand D and Sullivan, JP (1995) Stable expression and pharmacological properties of the human α7 nicotinic acetylcholine receptor. Eur J Pharmacol 290:237-246.
16. Lester RAJ and Dani JA (1994) Time dependent changes in central nicotinic acetylcholine channel kinetics in excised patches. Neuropharmacology 33:27-34.
17. Luetje CW and Patrick J (1991) Both α-and β-subunits contribute to the agonist sensitivity of neuronal nicotinic acetylcholine receptors. J Neurosci 11:837-845.
18. Lewis TM, Harkness PC, Sivilotti LG, Colquhoun D and Millar NS (1997) The ion channel properties of a rat neuronal nicotinic receptor are dependent on the host cell type. J Physiol (London) 505:299-306.
19. Lindstrom J (1997) Nicotinic acetylcholine receptors in health and disease. Mol Neurobiol 15:193-222.
20. Lovinger DM (1997) Alcohols and neurotransmitter gated ion channels: Past, present and future. Naunyn-Schmiedeberg's Arch Pharmacol 356:267-282.
21. Margiotta JK, Berg DK and Dionne VE (1987) Cyclic AMP regulates the proportion of function acetylcholine receptors on chicken ciliary ganglion neurons. Proc Natl Acad Sci USA 84:8155-8159.
22. Marszalec W and Narahashi T (1993) Use dependent pentobarbital block of kainate and quisqualate current. Brain Res 608:7-15.
23. Marzalec W, Aistrup GL and Narahashi T (1998) Ethanol modulation of excitatory and inhibitory synaptic interactions in cultured cortical neurons. Alcohol Clin Exp Res 22:1516-1524.
24. Miller KW, Wood SC, Forman SA, Bugge B, Hill WA and Abadji V (1991) The nicotinic acetylcholine receptor in its membrane environment. Ann N Y Acad Sci 625:600-615.
25. Mullikin-Kilpatrick D and Treistman SN (1993) Electrophysiological studies on calcium channels in naïve and ethanol-treated PC12 cells. Alcohol Alcoholism Suppl 2:385-389.
26. Nagata K, Aistrup GL, Huang CS, Marszalec W, Song J-H, Yeh JZ and Narahashi T (1996) Potent modulation of neuronal nicotinic acetylcholine receptor-channel by ethanol. Neurosci Lett 217:189-193.
27. Puchacz E, Buisson B, Bertrand D and Lukas RJ (1994) Functional expression of nicotinic acetycholine receptors containing rat α7 subunits in human SH-SY5Y neuroblastoma cells. FEBS Lett 354:155-159.
28. Rogers SW, Mandelzys A, Deneris ES, Cooper E and Heinemann S (1992) The expression of nicotinic acetylcholine receptors by PC12 cells treated with NGF. J Neurosci 12:4611-4623.
29. Role LW and Berg DK (1996) Nicotinic receptors in the development and modulation of CNS synapses. Neuron 16:1077-1085.
30. Sivilotti LG, McNeil DK, Lewis TM, Nassar MA, Schoepfer R and Colquhoun D (1997) Recombinant nicotinic receptors, expressed in Xenopus oocytes, do not resemble native rat sympathetic ganglion receptors in single-channel behavior. J Physiol (London) 500:123-138.
31. Violet JM, Downie DL, Nakisa RC, Lieb WR and Franks NP (1997) Differential sensitivities of mammalian neuronal nicotinic acetylcholine receptors to general anesthetics. Anesthesiology 86:866-874.
32. Weaver WR and Chiappinelli VA (1996) Single-channel recording in brain slices reveals heterogeneity of nicotinic receptors on individual neurons within the chick lateral spiriform nucleus. Brain Res 725:95-105.
33. Wonnacott S (1997) Presynaptic nicotinic ACh receptors. Trends Neurosci 20:92-98.
34. Wu G, Tonner PH and Miller KW (1994) Ethanol stabilizes the open channel state of the Torpedo nicotinic acetylcholine receptor. Mol Pharmacol 45:102-108.
35. Yu D, Zhang L, Eisele J-L, Bertrand D, Changeux J-P and Weight FF (1996) Ethanol inhibition of nicotinic acetylcholine type α7 receptors involves the amino-terminal domain of the receptor. Mol Pharmacol 50:1010-1016.
36. Zacny JP (1990) Behavioral aspects of alcohol-tobacco interactions. Recent Dev Alcohol 8:205-219.