The small molecule ferristatin II induces hepatic hepcidin expression in vivo and in vitro

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 308, Issue 12, 2015, Pages 1019-1026

  Alkhateeb, Ahmed A ^a   Buckett, Peter D ^a   Gardeck, Andrew M ^a   Kim, Jonghan ^b   Byrne, Shaina L ^a   Fraenke, Paula G ^c   Wessling Resnick, Marianne ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b NORTHEASTERN UNIVERSITY   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

BMP6; Hemochromatosis; IL 6; Iron transport

Indexed keywords

ALPHA 2 MACROGLOBULIN; BONE MORPHOGENETIC PROTEIN 6; C REACTIVE PROTEIN; FERRISTATIN II; HEPCIDIN; INHIBITOR OF DIFFERENTIATION 1; INTERLEUKIN 6; IRON; MESSENGER RNA; OROSOMUCOID; PEPTIDE HORMONE ANTAGONIST; SMAD PROTEIN; SMAD7 PROTEIN; STAT3 PROTEIN; TRANSFERRIN; UNCLASSIFIED DRUG; ANTIMICROBIAL CATIONIC PEPTIDE; BIPHENYL DERIVATIVE; MEMBRANE PROTEIN; SULFONE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; GENE EXPRESSION; HEPG2 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; IRON ABSORPTION; IRON BLOOD LEVEL; IRON KINETICS; LIVER; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; ANIMAL; DRUG EFFECTS; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; BIPHENYL COMPOUNDS; BONE MORPHOGENETIC PROTEIN 6; HEPCIDINS; HUMANS; INTERLEUKIN-6; LIVER; MEMBRANE PROTEINS; PHOSPHORYLATION; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; SULFONES;

EID: 84932117245     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00324.2014     Document Type: Article

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