In vivo regulation of gene expression and T helper type 17 differentiation by RORγt inverse agonists

Immunology

Volumn 145, Issue 3, 2015, Pages 347-356

  Skepner, Jill ^a   Trocha, Mark ^a   Ramesh, Radha ^a   Qu, Xiaoyan A ^a   Schmidt, Darby ^a   Baloglu, Erkan ^a,c   Lobera, Mercedes ^a   Davis, Scott ^a   Nolan, Michael A ^a   Carlson, Thaddeus J ^a   Hill, Jonathan ^a   Ghosh, Shomir ^a   Sundrud, Mark S ^a,b   Yang, Jianfei ^a  

^a GLAXOSMITHKLINE   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c Karyopharm Therapeutics   (United States)

Author keywords

Autoinflammatory disease; Cytokines; T cells

Indexed keywords

AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; CD45 ANTIGEN; CHEMOKINE RECEPTOR CCR6; FREUND ADJUVANT; GLYCOPROTEIN P 15095; IMMUNOMODULATING AGENT; INTERLEUKIN 17; INTERLEUKIN 17F; INTERLEUKIN 22; INTERLEUKIN 23 RECEPTOR; MYELIN; RETINOID RELATED ORPHAN RECEPTOR GAMMA; SMAD3 PROTEIN; TMP 778; UNCLASSIFIED DRUG; FUSED HETEROCYCLIC RINGS; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN (35-55); PEPTIDE FRAGMENT; TMP778;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CD4+ T LYMPHOCYTE; CELL MATURATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; FEMALE; GENE EXPRESSION REGULATION; IMMUNIZATION; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; TH1 CELL; TH17 CELL; TH2 CELL; AGONISTS; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL DIFFERENTIATION; DNA MICROARRAY; DRUG EFFECTS; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETICS; IMMUNOLOGY; METABOLISM; PROCEDURES;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; FEMALE; FREUND'S ADJUVANT; GENE EXPRESSION; GENE EXPRESSION PROFILING; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; IMMUNIZATION; MICE, INBRED C57BL; MYELIN-OLIGODENDROCYTE GLYCOPROTEIN; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 3; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PEPTIDE FRAGMENTS; TH17 CELLS;

EID: 84931577361     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12444     Document Type: Article

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