Notch receptor-ligand engagement maintains hematopoietic stem cell quiescence and niche retention

Stem Cells

Volumn 33, Issue 7, 2015, Pages 2280-2293

  Wang, Weihuan ^a   Yu, Shuiliang ^a   Zimmerman, Grant ^a   Wang, Yiwei ^a   Myers, Jay ^a   Yu, Vionnie W C ^b,c,d   Huang, Dan ^a   Huang, Xiaoran ^a   Shim, Jeongsup ^e   Huang, Yuanshuai ^f   Xin, William ^g   Qiao, Peter ^a   Yan, Minhong ^e   Xin, Wei ^a   Scadden, David T ^b,c,d   Stanley, Pamela ^h   Lowe, John B ^e   Huang, Alex Y ^a   Siebel, Christian W ^e   Zhou, Lan ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^c HARVARD STEM CELL INSTITUTE   (United States)

^d Harvard University   (United States)

^e GENENTECH INC   (United States)

^f SOUTHWEST MEDICAL UNIVERSITY   (China)

^g University School   (United States)

^h ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

HSC egress and mobilization; HSC quiescence and niche retention; Notch receptor ligand interactions; O fucosylglycans on Notch

Indexed keywords

NEUTRALIZING ANTIBODY; NOTCH RECEPTOR;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL PROLIFERATION; CONTROLLED STUDY; HEMATOPOIETIC STEM CELL; LIGAND BINDING; MOUSE; NONHUMAN; OSTEOBLAST; PERIPHERAL CIRCULATION; PHENOTYPE; STEM CELL NICHE; STROMA CELL; ANIMAL; GENETICS; HUMAN; METABOLISM; SIGNAL TRANSDUCTION;

MUS;

ANIMALS; HEMATOPOIETIC STEM CELLS; HUMANS; MICE; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; STEM CELL NICHE; STROMAL CELLS;

EID: 84931573706     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.2031     Document Type: Article

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