O-fucosylation of the NOTCH ligand MDll1 by POFUT1 is dispensable for ligand function

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Müller, Julia ^a,c   Rana, Nadia A ^b   Serth, Katrin ^a   Kakuda, Shinako ^b   Haltiwanger, Robert S ^b   Gossler, Achim ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b STONY BROOK UNIVERSITY   (United States)

^c Anwaltssozietaet Boehmert and Boehmert   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; FUCOSYLTRANSFERASE; NOTCH LIGAND DELTA LIKE 1; NOTCH RECEPTOR; PROTEIN POFUT1; UNCLASSIFIED DRUG; VALINE; DLK1 PROTEIN, MOUSE; EPIDERMAL GROWTH FACTOR; FUCOSE; LIGAND; POFUT1 PROTEIN, MOUSE; SIGNAL PEPTIDE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOTINYLATION; CELL SURFACE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; EMBRYO; ENDOPLASMIC RETICULUM; ENDOSOME; FUCOSYLATION; GOLGI COMPLEX; HUMAN; HUMAN CELL; MOUSE; MUTATION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEOMICS; ANIMAL; CELL LINE; CELL MEMBRANE; CHEMISTRY; CHO CELL LINE; CRICETULUS; FIBROBLAST; GENETICS; LIQUID CHROMATOGRAPHY; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROCEDURES; SEQUENCE HOMOLOGY; TANDEM MASS SPECTROMETRY; TRANSCRIPTION INITIATION;

ANIMALS; BASE SEQUENCE; CELL LINE; CELL MEMBRANE; CHO CELLS; CHROMATOGRAPHY, LIQUID; CRICETULUS; EPIDERMAL GROWTH FACTOR; FIBROBLASTS; FUCOSE; FUCOSYLTRANSFERASES; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGANDS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; PROTEOMICS; RECEPTORS, NOTCH; SEQUENCE HOMOLOGY, NUCLEIC ACID; TANDEM MASS SPECTROMETRY; TRANSCRIPTIONAL ACTIVATION;

EID: 84895760653     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088571     Document Type: Article

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