Synergistic mobilization of hemopoietic progenitor cells using concurrent β1 and β2 integrin blockade or β2-deficient mice

Blood

Volumn 97, Issue 5, 2001, Pages 1282-1288

  Papayannopoulou, Thalia ^a   Priestley, Gregory V ^a   Nakamoto, Betty ^a   Zafiropoulos, Vivian ^a   Scott, Linda M ^a   Harlan, John M ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; INTEGRIN;

ANIMAL CELL; ANTIBODY PRODUCTION; ARTICLE; CELL ADHESION; CELL MIGRATION; CELL MOTILITY; HEMATOPOIETIC STEM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0035283078     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V97.5.1282     Document Type: Article

References (38)

1. The biology and clinical uses of blood stem cells
2. Integrins: Versatility, modulation, and signaling in cell adhesion
3. Evidence for a role of the integrin VLA4 in lympho-hemopoiesis
4. hi stem cells to bone marrow stroma
5. VLA4 and VCAM-1 are the principal adhesion molecules involved in the interaction between blast colony-forming cells and bone marrow stromal cells
6. Impaired migration but not differentiation of haematopoietic stem cells in the absence of β1 integrins
7. α4 integrins regulate the proliferation/differentiation balance of multilineage hematopoietic progenitors in vivo
8. Antibodies to VLA4 integrin mobilize long-term repopulating cells and augment cytokine-induced mobilization in primates and mice
9. The role of CS1 moiety of fibronectin in VLA4-mediated haemopoietic progenitor trafficking
10. Role of adhesion molecules in the homing and mobilization of murine hematopoietic stem and progenitor cells
11. Peripheralization of hemopoietic progenitors in primates treated with anti-VLA4 integrin
12. Mobilization of hematopoietic primitive and committed progenitor cells into blood in mice by anti-vascular adhesion molecule-1 antibody alone or in combination with granulocyte colony-stimulating factor
13. Leukocyte-endothelial adhesion molecules
14. Leukocyte adhesion deficiency syndrome: Insights into the molecular basis of leukocyte emigration
15. Monocyte migration to arthritis in the rat utilizes both CD11/CD18 and very late activation antigen 4 integrin mechanisms
16. Gene targeting yields a CD18-mutant mouse for study of inflammation
17. Spontaneous skin ulceration and defective T cell function in CD18 null mice
18. Definition of a common leukocyte cell-surface antigen (Lp95-150) associated with diverse cell-mediated immune functions
19. Functional evidence for three distinct and independently inhibitable adhesion activities mediated by the human integrin VLA4: Correlation with distinct α4 epitopes
20. Anti-VLA4/VCAM-1-induced mobilization requires cooperative signaling through the kit/mkit ligand pathway
21. Anti-LFA-1 blocking antibodies prevent mobilization of hematopoietic progenitor cells induced by interleukin-8
22. Blocking lymphoma invasiveness with a monoclonal antibody directed against the β-chain of the leukocyte adhesion molecule (CD18)
23. Inhibition and stimulation of LFA-1 and Mac-1 functions by antibodies against murine CD18: Evidence that the LFA-1 binding sites for ICAM-1, -2, and -3 are distinct
24. CD18-independent neutrophil and mononuclear leukocyte emigration into the peritoneum of rabbits
25. Inhibition of CD18-dependent neutrophil adherence reduces organ injury after hemorrhagic shock in primates
26. Anti-P-selectin monoclonal antibody attenuates reperfusion injury to the rabbit ear
27. Homing of human cells in the fetal sheep model: Modulation by antibodies activating or inhibiting very late activation antigen-4-dependent function
28. Selective requirements for leukocyte adhesion molecules in models of acute and chronic cutaneous inflammation: Participation of E- and P- but not L-selectin
29. Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration
30. Adhesion receptors on bone marrow stromal cells: In vivo expression of vascular cell adhesion molecule-1 by reticular cells and sinusoidal endothelium in normal and γ-irradiated mice
31. Cell migration: A physically integrated molecular process
32. Murine hematopoietic progenitor cells with colony-forming or radioprotective capacity lack expression of the β2-integrin LFA-1
33. Integrin expression profiles during erythroid differentiation
34. Lymphocyte migration in lymphocyte function-associated antigen (LFA)-1-deficient mice
35. VLA-4 (α4β1) engagement defines a novel activation pathway for β2 integrin-dependent leukocyte adhesion involving the urokinase receptor
36. Dual inhibition of VLA-4 and LFA-1 maximally inhibits cutaneous delayed-type hypersensitivity-induced inflammation
37. Mechanisms of acute eosinophil mobilization from the bone marrow stimulated by interleukin 5: The role of specific adhesion molecules and phosphatidylinositol 3-kinase
38. Integrin cross talk: Activation of lymphocyte function-associated antigen-1 on human T cells alters α4β1 and α5β1 -mediated function