Early life lead exposure causes gender-specific changes in the DNA methylation profile of DNA extracted from dried blood spots

Epigenomics

Volumn 7, Issue 3, 2015, Pages 379-393

  Sen, Arko ^a,b   Heredia, Nicole ^b   Senut, Marie Claude ^a   Hess, Matthew ^b,c   Land, Susan ^b   Qu, Wen ^b   Hollacher, Kurt ^d   Dereski, Mary O ^b   Ruden, Douglas M ^a,d  

^a WAYNE STATE UNIVERSITY   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNION COLLEGE   (United States)

Author keywords

blood lead levels; differential methylation; DNA methylation; dried blood spots; epigenetics; gene specific; lead; whole blood

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR GAMMA1; CYTOCHROME P450 1A1; DNA; EXTRACELLULAR SUPEROXIDE DISMUTASE; GLUTATHIONE PEROXIDASE 1; LEAD; SEROTONIN TRANSPORTER; TRANSCRIPTION FACTOR DP1; TRANSCRIPTION FACTOR RUNX1; TRANSCRIPTION FACTOR RUNX3;

ARTICLE; CHILD; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DRIED BLOOD SPOT TESTING; ENVIRONMENTAL EXPOSURE; FEMALE; GENE LOCUS; GENE ONTOLOGY; GESTATIONAL AGE; HUMAN; HUMAN GENOME; INFANT; LEAD BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MITOCHONDRIAL GENE; OXIDATIVE STRESS; PILOT STUDY; PRESCHOOL CHILD; PRIORITY JOURNAL; PROMOTER REGION; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; TRANSCRIPTION INITIATION SITE; BLOOD; DRUG EFFECTS; ISOLATION AND PURIFICATION;

CHILD, PRESCHOOL; DNA; DNA METHYLATION; ENVIRONMENTAL EXPOSURE; FEMALE; GENES, MITOCHONDRIAL; HUMANS; INFANT; LEAD; MALE; PILOT PROJECTS; SEX FACTORS;

EID: 84931315666     PISSN: 17501911     EISSN: 1750192X     Source Type: Journal    
DOI: 10.2217/epi.15.2     Document Type: Article

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