Epigenetic modification of the leptin promoter in diet-induced obese mice and the effects of N-3 polyunsaturated fatty acids

Scientific Reports

Volumn 4, Issue , 2014, Pages

  Shen, Wenwen ^a   Wang, Cui ^a   Xia, Lulu ^a   Fan, Chaonan ^a   Dong, Hua ^a   Deckelbaum, Richard J ^b   Qi, Kemin ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA BINDING PROTEIN; HISTONE; HISTONE DEACETYLASE; LEPTIN; MBD2 PROTEIN, MOUSE; OMEGA 3 FATTY ACID; PROTEIN BINDING; RNA POLYMERASE II;

ACETYLATION; ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; CPG ISLAND; DNA METHYLATION; DRUG EFFECTS; GENE EXPRESSION; GENETIC EPIGENESIS; GENETICS; LIPID DIET; MALE; METABOLISM; METHYLATION; OBESITY; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ACETYLATION; ANIMALS; CPG ISLANDS; DIET, HIGH-FAT; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DNA-BINDING PROTEINS; EPIGENESIS, GENETIC; FATTY ACIDS, OMEGA-3; GENE EXPRESSION; HISTONE DEACETYLASES; HISTONES; LEPTIN; MALE; METHYLATION; MICE, INBRED C57BL; OBESITY; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA POLYMERASE II;

EID: 84902491569     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep05282     Document Type: Article

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