메뉴 건너뛰기




Volumn 122, Issue 4, 2013, Pages 562-566

Runx3 deficiency results in myeloproliferative disorder in aged mice

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; TRANSCRIPTION FACTOR RUNX3; RUNX3 PROTEIN, MOUSE;

EID: 84886941879     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-10-460618     Document Type: Article
Times cited : (25)

References (24)
  • 1
    • 36348962321 scopus 로고    scopus 로고
    • Runx genes in development and cancer: Regulation of viral gene expression and the discovery of runx family genes
    • Ito Y. RUNX genes in development and cancer: regulation of viral gene expression and the discovery of RUNX family genes. Adv Cancer Res. 2008;99:33-76.
    • (2008) Adv Cancer Res. , vol.99 , pp. 33-76
    • Ito, Y.1
  • 2
    • 2942659322 scopus 로고    scopus 로고
    • Oncogenic potential of the runx gene family: ‘overview’
    • Ito Y. Oncogenic potential of the RUNX gene family: ‘overview’. Oncogene. 2004;23(24): 4198-4208.
    • (2004) Oncogene , vol.23 , Issue.24 , pp. 4198-4208
    • Ito, Y.1
  • 3
    • 0036636857 scopus 로고    scopus 로고
    • Core-binding factors in haematopoiesis and leukaemia
    • Speck NA, Gilliland DG. Core-binding factors in haematopoiesis and leukaemia. Nat Rev Cancer. 2002;2(7):502-513.
    • (2002) Nat Rev Cancer , vol.2 , Issue.7 , pp. 502-513
    • Speck, N.A.1    Gilliland, D.G.2
  • 4
    • 2942667930 scopus 로고    scopus 로고
    • Point mutations in the Runx1/aml1 gene: Another actor in runx leukemia
    • Osato M. Point mutations in the RUNX1/AML1 gene: another actor in RUNX leukemia. Oncogene. 2004;23(24):4284-4296.
    • (2004) Oncogene , vol.23 , Issue.24 , pp. 4284-4296
    • Osato, M.1
  • 5
    • 0033559746 scopus 로고    scopus 로고
    • Biallelic and heterozygous point mutations in the runt domain of the Aml1/pebp2alphab gene associated with myeloblastic leukemias
    • Osato M, Asou N, Abdalla E, et al. Biallelic and heterozygous point mutations in the runt domain of the AML1/PEBP2alphaB gene associated with myeloblastic leukemias. Blood. 1999;93(6): 1817-1824.
    • (1999) Blood , vol.93 , Issue.6 , pp. 1817-1824
    • Osato, M.1    Asou, N.2    Abdalla, E.3
  • 6
    • 37349112219 scopus 로고    scopus 로고
    • Runx1 protects hematopoietic stem/progenitor cells from oncogenic insult
    • Motoda L, Osato M, Yamashita N, et al. Runx1 protects hematopoietic stem/progenitor cells from oncogenic insult. Stem Cells. 2007;25(12): 2976-2986.
    • (2007) Stem Cells , vol.25 , Issue.12 , pp. 2976-2986
    • Motoda, L.1    Osato, M.2    Yamashita, N.3
  • 7
    • 77949888952 scopus 로고    scopus 로고
    • Stem cell exhaustion due to runx1 deficiency is prevented by evi5 activation in leukemogenesis
    • Jacob B, Osato M, Yamashita N, et al. Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis. Blood. 2010;115(8):1610-1620.
    • (2010) Blood , vol.115 , Issue.8 , pp. 1610-1620
    • Jacob, B.1    Osato, M.2    Yamashita, N.3
  • 8
    • 66749121358 scopus 로고    scopus 로고
    • Stem cell exhaustion and leukemogenesis
    • Jacob B, Osato M. Stem cell exhaustion and leukemogenesis. J Cell Biochem. 2009;107(3): 393-399.
    • (2009) J Cell Biochem , vol.107 , Issue.3 , pp. 393-399
    • Jacob, B.1    Osato, M.2
  • 9
    • 54949109765 scopus 로고    scopus 로고
    • Runx1/aml1 is a guardian of hematopoietic stem cells
    • Motoda L, Osato M, Ito Y. Runx1/AML1 is a guardian of hematopoietic stem cells. Curr Cancer Therap Rev. 2008;4(3):188-195.
    • (2008) Curr Cancer Therap Rev. , vol.4 , Issue.3 , pp. 188-195
    • Motoda, L.1    Osato, M.2    Ito, Y.3
  • 10
    • 77950296390 scopus 로고    scopus 로고
    • Runx family genes, niche, and stem cell quiescence
    • Wang CQ, Jacob B, Nah GS, Osato M. Runx family genes, niche, and stem cell quiescence. Blood Cells Mol Dis. 2010;44(4):275-286.
    • (2010) Blood Cells Mol Dis. , vol.44 , Issue.4 , pp. 275-286
    • Wang, C.Q.1    Jacob, B.2    Nah, G.S.3    Osato, M.4
  • 11
    • 22144447520 scopus 로고    scopus 로고
    • Loss of runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype
    • Growney JD, Shigematsu H, Li Z, et al. Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype. Blood. 2005;106(2):494-504.
    • (2005) Blood , vol.106 , Issue.2 , pp. 494-504
    • Growney, J.D.1    Shigematsu, H.2    Li, Z.3
  • 12
    • 2342451948 scopus 로고    scopus 로고
    • Aml-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis
    • Ichikawa M, Asai T, Saito T, et al. AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis. Nat Med. 2004;10(3):299-304.
    • (2004) Nat Med. , vol.10 , Issue.3 , pp. 299-304
    • Ichikawa, M.1    Asai, T.2    Saito, T.3
  • 13
    • 32544445732 scopus 로고    scopus 로고
    • Aml1 deletion in adult mice causes splenomegaly and lymphomas
    • Putz G, Rosner A, Nuesslein I, Schmitz N, Buchholz F. AML1 deletion in adult mice causes splenomegaly and lymphomas. Oncogene. 2006; 25(6):929-939.
    • (2006) Oncogene , vol.25 , Issue.6 , pp. 929-939
    • Putz, G.1    Rosner, A.2    Nuesslein, I.3    Schmitz, N.4    Buchholz, F.5
  • 14
    • 18744398397 scopus 로고    scopus 로고
    • Differential requirements for runx proteins in cd4 repression and epigenetic silencing during t lymphocyte development
    • Taniuchi I, Osato M, Egawa T, et al. Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development. Cell. 2002;111(5):621-633.
    • (2002) Cell , vol.111 , Issue.5 , pp. 621-633
    • Taniuchi, I.1    Osato, M.2    Egawa, T.3
  • 15
    • 34547656115 scopus 로고    scopus 로고
    • Cdna cloning of runx family genes from the pufferfish (fugu rubripes)
    • Ng CE, Osato M, Tay BH, Venkatesh B, Ito Y. cDNA cloning of Runx family genes from the pufferfish (Fugu rubripes). Gene. 2007;399(2): 162-173.
    • (2007) Gene , vol.399 , Issue.2 , pp. 162-173
    • Ng, C.E.1    Osato, M.2    Tay, B.H.3    Venkatesh, B.4    Ito, Y.5
  • 16
    • 34547727747 scopus 로고    scopus 로고
    • Repression of interleukin-4 in t helper type 1 cells by runx/cbf beta binding to the il4 silencer
    • Naoe Y, Setoguchi R, Akiyama K, et al. Repression of interleukin-4 in T helper type 1 cells by Runx/Cbf beta binding to the Il4 silencer. J Exp Med. 2007;204(8):1749-1755.
    • (2007) J Exp Med. , vol.204 , Issue.8 , pp. 1749-1755
    • Naoe, Y.1    Setoguchi, R.2    Akiyama, K.3
  • 17
    • 33644827383 scopus 로고    scopus 로고
    • Bone-marrow haematopoietic-stem-cell niches
    • Wilson A, Trumpp A. Bone-marrow haematopoietic-stem-cell niches. Nat Rev Immunol. 2006;6(2):93-106.
    • (2006) Nat Rev Immunol. , vol.6 , Issue.2 , pp. 93-106
    • Wilson, A.1    Trumpp, A.2
  • 18
    • 4243392328 scopus 로고    scopus 로고
    • Hematological analysis of Aml1/pebp2 alpha b+/- mice: A possible predisposition to myeloid leukemia
    • Cottles GM, Osato M, Yokomizo T, et al. Hematological analysis of AML1/PEBP2 alpha B+/- mice: A possible predisposition to myeloid leukemia. Blood. 1999;94(10):218b.
    • (1999) Blood , vol.94 , Issue.10 , pp. 218b
    • Cottles, G.M.1    Osato, M.2    Yokomizo, T.3
  • 19
    • 0030999555 scopus 로고    scopus 로고
    • A breakpoint map of recurrent chromosomal rearrangements in human neoplasia
    • Mitelman F, Mertens F, Johansson B. A breakpoint map of recurrent chromosomal rearrangements in human neoplasia. Nat Genet. 1997;15(Spec No):417-474.
    • (1997) Nat Genet. , vol.15 , Issue.Spec No , pp. 417-474
    • Mitelman, F.1    Mertens, F.2    Johansson, B.3
  • 20
    • 0030929119 scopus 로고    scopus 로고
    • Allelotype analysis in the evolution of chronic myelocytic leukemia
    • Mori N, Morosetti R, Lee S, et al. Allelotype analysis in the evolution of chronic myelocytic leukemia. Blood. 1997;90(5):2010-2014.
    • (1997) Blood , vol.90 , Issue.5 , pp. 2010-2014
    • Mori, N.1    Morosetti, R.2    Lee, S.3
  • 22
    • 84924590755 scopus 로고    scopus 로고
    • Epigenetic silencing of the runx3 gene by promoter hypermethylation in patients with acute myeloid leukemia
    • Maddipoti SC, Bueso-Ramos C, Yang H, et al. Epigenetic silencing of the RUNX3 gene by promoter hypermethylation in patients with acute myeloid leukemia. Blood. 2008;112(11):3341.
    • (2008) Blood , vol.112 , Issue.11 , pp. 3341
    • Maddipoti, S.C.1    Bueso-Ramos, C.2    Yang, H.3
  • 23
    • 54049106547 scopus 로고    scopus 로고
    • Transcriptional repression of the Runx3/aml2 gene by the t(8; 21) and inv(16) fusion proteins in acute myeloid leukemia
    • Cheng CK, Li L, Cheng SH, et al. Transcriptional repression of the RUNX3/AML2 gene by the t(8; 21) and inv(16) fusion proteins in acute myeloid leukemia. Blood. 2008;112(8):3391-3402.
    • (2008) Blood , vol.112 , Issue.8 , pp. 3391-3402
    • Cheng, C.K.1    Li, L.2    Cheng, S.H.3
  • 24
    • 20144367446 scopus 로고    scopus 로고
    • Gene expression profile reveals deregulation of genes with relevant functions in the different subclasses of acute myeloid leukemia
    • Gutiérrez NC, López-Pérez R, Hernández JM, et al. Gene expression profile reveals deregulation of genes with relevant functions in the different subclasses of acute myeloid leukemia. Leukemia. 2005;19(3):402-409.
    • (2005) Leukemia , vol.19 , Issue.3 , pp. 402-409
    • Gutiérrez, N.C.1    López-Pérez, R.2    Hernández, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.