VWF excess and ADAMTS13 deficiency: A unifying pathomechanism linking inflammation to thrombosis in DIC, malaria, and TTP

Thrombosis and Haemostasis

Volumn 113, Issue 4, 2015, Pages 708-718

  Schwameis, Michael ^a   Schörgenhofer, Christian ^a   Assinger, Alice ^a   Steiner, Margarete M ^a   Jilma, Bernd ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

ADAMTS13; DIC; Malaria; Sepsis; TTP; VWF

Indexed keywords

APTAMER; INTERLEUKIN 6; INTERLEUKIN 8; LEUKOCYTE ELASTASE; LIPOPOLYSACCHARIDE; NANOBODY; PLASMIN; REACTIVE OXYGEN METABOLITE; THROMBIN; THROMBOSPONDIN 1; TUMOR NECROSIS FACTOR ALPHA; VON WILLEBRAND FACTOR; VON WILLEBRAND FACTOR CLEAVING PROTEINASE; ADAM PROTEIN; ADAMTS13 PROTEIN, HUMAN; BIOLOGICAL MARKER; FIBRINOLYTIC AGENT;

DISSEMINATED INTRAVASCULAR CLOTTING; ENZYME ACTIVITY; ENZYME DEFICIENCY; HUMAN; INFLAMMATION; MALARIA; MALARIA FALCIPARUM; NONHUMAN; PHASE 2 CLINICAL TRIAL (TOPIC); PLASMAPHERESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; REVIEW; SEPSIS; THROMBOCYTE COUNT; THROMBOSIS; THROMBOTIC THROMBOCYTOPENIC PURPURA; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; DEFICIENCY; DISSEMINATED INTRAVASCULAR COAGULATION; ENZYME REPLACEMENT; ENZYMOLOGY; MALARIA, FALCIPARUM; METABOLISM; PROTEIN MULTIMERIZATION; PURPURA, THROMBOTIC THROMBOCYTOPENIC; THROMBOTIC MICROANGIOPATHIES; UPREGULATION;

ADAM PROTEINS; ADAMTS13 PROTEIN; ANIMALS; BIOMARKERS; DISSEMINATED INTRAVASCULAR COAGULATION; ENZYME REPLACEMENT THERAPY; FIBRINOLYTIC AGENTS; HUMANS; INFLAMMATION; MALARIA, FALCIPARUM; PROTEIN MULTIMERIZATION; PURPURA, THROMBOTIC THROMBOCYTOPENIC; THROMBOSIS; THROMBOTIC MICROANGIOPATHIES; UP-REGULATION; VON WILLEBRAND FACTOR;

EID: 84931291702     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH14-09-0731     Document Type: Review

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