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Volumn 40, Issue 5, 2014, Pages 544-550

Thrombotic microangiopathies and the linkage between von Willebrand factor and the alternative complement pathway

Author keywords

alternative complement pathway; factor H; thrombotic microangiopathies; VWF

Indexed keywords

COMPLEMENT; COMPLEMENT FACTOR H; POLYMER; VON WILLEBRAND FACTOR; VON WILLEBRAND FACTOR CLEAVING PROTEINASE; COMPLEMENT MEMBRANE ATTACK COMPLEX;

EID: 84905223622     PISSN: 00946176     EISSN: 10989064     Source Type: Journal    
DOI: 10.1055/s-0034-1383547     Document Type: Article
Times cited : (42)

References (56)
  • 1
    • 77957581427 scopus 로고    scopus 로고
    • Hemolytic uremic syndrome. Preface
    • Favaloro E. J. Hemolytic uremic syndrome. Preface. Semin Thromb Hemost: 2010; 36 6 573 574
    • (2010) Semin Thromb Hemost , vol.36 , Issue.6 , pp. 573-574
    • Favaloro, E.J.1
  • 2
    • 84902149202 scopus 로고    scopus 로고
    • An update on the thrombotic microangiopathies hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP)
    • Riedl M., Orth-Höller D., Würzner R. An update on the thrombotic microangiopathies hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP). Semin Thromb Hemost: 2014; 40 413 415
    • (2014) Semin Thromb Hemost , vol.40 , pp. 413-415
    • Riedl, M.1    Orth-Höller, D.2    Würzner, R.3
  • 3
    • 84875597120 scopus 로고    scopus 로고
    • Assembly and activation of alternative complement components on endothelial cell-anchored ultra-large von Willebrand factor links complement and hemostasis-thrombosis
    • Turner N. A., Moake J. Assembly and activation of alternative complement components on endothelial cell-anchored ultra-large von Willebrand factor links complement and hemostasis-thrombosis. PLoS ONE: 2013; 8 3 e59372
    • (2013) PLoS ONE , vol.8 , Issue.3
    • Turner, N.A.1    Moake, J.2
  • 4
    • 84857017558 scopus 로고    scopus 로고
    • Generation and breakdown of soluble ultralarge von Willebrand factor multimers
    • Turner N., Nolasco L., Moake J. Generation and breakdown of soluble ultralarge von Willebrand factor multimers. Semin Thromb Hemost: 2012; 38 1 38 46
    • (2012) Semin Thromb Hemost , vol.38 , Issue.1 , pp. 38-46
    • Turner, N.1    Nolasco, L.2    Moake, J.3
  • 5
    • 84887122022 scopus 로고    scopus 로고
    • Human complement factor H is a reductase for large soluble von Willebrand factor multimers-brief report
    • Nolasco L., Nolasco J., Feng S., Afshar-Kharghan V., Moake J. Human complement factor H is a reductase for large soluble von Willebrand factor multimers-brief report. Arterioscler Thromb Vasc Biol: 2013; 33 11 2524 2528
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , Issue.11 , pp. 2524-2528
    • Nolasco, L.1    Nolasco, J.2    Feng, S.3    Afshar-Kharghan, V.4    Moake, J.5
  • 6
    • 0037158606 scopus 로고    scopus 로고
    • Thrombotic microangiopathies
    • Moake J. L. Thrombotic microangiopathies. N Engl J Med: 2002; 347 8 589 600
    • (2002) N Engl J Med , vol.347 , Issue.8 , pp. 589-600
    • Moake, J.L.1
  • 8
    • 0030973267 scopus 로고    scopus 로고
    • Deficient activity of von Willebrand factor-cleaving protease in chronic relapsing thrombotic thrombocytopenic purpura
    • Furlan M., Robles R., Solenthaler M., Wassmer M., Sandoz P., Lämmle B. Deficient activity of von Willebrand factor-cleaving protease in chronic relapsing thrombotic thrombocytopenic purpura. Blood: 1997; 89 9 3097 3103 (Pubitemid 27229791)
    • (1997) Blood , vol.89 , Issue.9 , pp. 3097-3103
    • Furlan, M.1    Rubles, R.2    Solenthaler, M.3    Wassmer, M.4    Sandoz, P.5    Lammle, B.6
  • 9
    • 0032569840 scopus 로고    scopus 로고
    • Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura
    • DOI 10.1056/NEJM199811263392203
    • Tsai H. M., Lian E. C. Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura. N Engl J Med: 1998; 339 22 1585 1594 (Pubitemid 28536133)
    • (1998) New England Journal of Medicine , vol.339 , Issue.22 , pp. 1585-1594
    • Tsai, H.-M.1    Lian, E.C.-Y.2
  • 11
    • 77952682366 scopus 로고    scopus 로고
    • Mutations in alternative pathway complement proteins in American patients with atypical hemolytic uremic syndrome
    • Maga T. K., Nishimura C. J., Weaver A. E., Frees K. L., Smith R. JH. Mutations in alternative pathway complement proteins in American patients with atypical hemolytic uremic syndrome. Hum Mutat: 2010; 31 6 E1445 E1460
    • (2010) Hum Mutat , vol.31 , Issue.6
    • Maga, T.K.1    Nishimura, C.J.2    Weaver, A.E.3    Frees, K.L.4    Smith, R.J.5
  • 12
    • 34047200899 scopus 로고    scopus 로고
    • Deletion of complement factor H-related genes CFHR1 and CFHR3 is associated with atypical hemolytic uremic syndrome
    • Zipfel P. F., Edey M., Heinen S., et al. Deletion of complement factor H-related genes CFHR1 and CFHR3 is associated with atypical hemolytic uremic syndrome. PLoS Genet: 2007; 3 3 e41
    • (2007) PLoS Genet , vol.3 , Issue.3
    • Zipfel, P.F.1    Edey, M.2    Heinen, S.3
  • 13
    • 54049137505 scopus 로고    scopus 로고
    • Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome
    • Frémeaux-Bacchi V., Miller E. C., Liszewski M. K., et al. Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome. Blood: 2008; 112 13 4948 4952
    • (2008) Blood , vol.112 , Issue.13 , pp. 4948-4952
    • Frémeaux-Bacchi, V.1    Miller, E.C.2    Liszewski, M.K.3
  • 17
    • 57649162572 scopus 로고    scopus 로고
    • Discrimination between host and pathogens by the complement system
    • 08
    • Pangburn M. K., Ferreira V. P., Cortes C. Discrimination between host and pathogens by the complement system. Vaccine: 2008; 26 8 08 I15 I21
    • (2008) Vaccine , vol.26 , Issue.8
    • Pangburn, M.K.1    Ferreira, V.P.2    Cortes, C.3
  • 18
    • 0031043135 scopus 로고    scopus 로고
    • The internal thioester and the covalent binding properties of the complement proteins C3 and C4
    • Law S. K., Dodds A. W. The internal thioester and the covalent binding properties of the complement proteins C3 and C4. Protein Sci: 1997; 6 2 263 274 (Pubitemid 27079917)
    • (1997) Protein Science , vol.6 , Issue.2 , pp. 263-274
    • Law, S.K.A.1    Dodds, A.W.2
  • 20
    • 0015744783 scopus 로고
    • Formation of a hemolytically active cellular intermediate by the interaction between properdin factors B and D and the activated third component of complement
    • Fearon D. T., Austen K. F., Ruddy S. Formation of a hemolytically active cellular intermediate by the interaction between properdin factors B and D and the activated third component of complement. J Exp Med: 1973; 138 6 1305 1313
    • (1973) J Exp Med , vol.138 , Issue.6 , pp. 1305-1313
    • Fearon, D.T.1    Austen, K.F.2    Ruddy, S.3
  • 21
    • 0000719411 scopus 로고
    • The properdin system and immunity. I. Demonstration and isolation of a new serum protein, properdin, and its role in immune phenomena
    • Pillemer L., Blum L., Lepow I. H., Ross O. A., Todd E. W., Wardlaw A. C. The properdin system and immunity. I. Demonstration and isolation of a new serum protein, properdin, and its role in immune phenomena. Science: 1954; 120 3112 279 285
    • (1954) Science , vol.120 , Issue.3112 , pp. 279-285
    • Pillemer, L.1    Blum, L.2    Lepow, I.H.3    Ross, O.A.4    Todd, E.W.5    Wardlaw, A.C.6
  • 22
    • 0012042656 scopus 로고
    • Control of the amplification convertase of complement by the plasma protein beta1H
    • Weiler J. M., Daha M. R., Austen K. F., Fearon D. T. Control of the amplification convertase of complement by the plasma protein beta1H. Proc Natl Acad Sci U S A: 1976; 73 9 3268 3272
    • (1976) Proc Natl Acad Sci U S A , vol.73 , Issue.9 , pp. 3268-3272
    • Weiler, J.M.1    Daha, M.R.2    Austen, K.F.3    Fearon, D.T.4
  • 23
    • 0024159572 scopus 로고
    • C5 convertase of the alternative complement pathway: Covalent linkage between two C3b molecules within the trimolecular complex enzyme
    • Kinoshita T., Takata Y., Kozono H., Takeda J., Hong K. S., Inoue K. C5 convertase of the alternative complement pathway: covalent linkage between two C3b molecules within the trimolecular complex enzyme. J Immunol: 1988; 141 11 3895 3901
    • (1988) J Immunol , vol.141 , Issue.11 , pp. 3895-3901
    • Kinoshita, T.1    Takata, Y.2    Kozono, H.3    Takeda, J.4    Hong, K.S.5    Inoue, K.6
  • 24
    • 0035865060 scopus 로고    scopus 로고
    • Formation of high-affinity C5 convertases of the alternative pathway of complement
    • Rawal N., Pangburn M. Formation of high-affinity C5 convertases of the alternative pathway of complement. J Immunol: 2001; 166 4 2635 2642 (Pubitemid 32173502)
    • (2001) Journal of Immunology , vol.166 , Issue.4 , pp. 2635-2642
    • Rawal, N.1    Pangburn, M.K.2
  • 25
    • 3042839778 scopus 로고    scopus 로고
    • Effects of inflammatory cytokines on the release and cleavage of the endothelial cell-derived ultralarge von Willebrand-factor multimers under flow
    • DOI 10.1182/blood-2004-01-0107
    • Bernardo A., Ball C., Nolasco L., Moake J. F., Dong J. F. Effects of inflammatory cytokines on the release and cleavage of the endothelial cell-derived ultralarge von Willebrand factor multimers under flow. Blood: 2004; 104 1 100 106 (Pubitemid 38879844)
    • (2004) Blood , vol.104 , Issue.1 , pp. 100-106
    • Bernardo, A.1    Ball, C.2    Nolasco, L.3    Moake, J.F.4    Dong, J.-F.5
  • 26
    • 78149336370 scopus 로고    scopus 로고
    • Shiga toxin B subunits induce VWF secretion by human endothelial cells and thrombotic microangiopathy in ADAMTS13-deficient mice
    • Huang J., Motto D. G., Bundle D. R., Sadler J. E. Shiga toxin B subunits induce VWF secretion by human endothelial cells and thrombotic microangiopathy in ADAMTS13-deficient mice. Blood: 2010; 116 18 3653 3659
    • (2010) Blood , vol.116 , Issue.18 , pp. 3653-3659
    • Huang, J.1    Motto, D.G.2    Bundle, D.R.3    Sadler, J.E.4
  • 27
    • 28844503491 scopus 로고    scopus 로고
    • Hemolytic uremic syndrome-associated Shiga toxins promote endothelial-cell secretion and impair ADAMTS13 cleavage of unusually large von Willebrand factor multimers
    • DOI 10.1182/blood-2005-05-2111
    • Nolasco L. H., Turner N. A., Bernardo A., et al. Hemolytic uremic syndrome-associated Shiga toxins promote endothelial-cell secretion and impair ADAMTS13 cleavage of unusually large von Willebrand factor multimers. Blood: 2005; 106 13 4199 4209 (Pubitemid 41775927)
    • (2005) Blood , vol.106 , Issue.13 , pp. 4199-4209
    • Nolasco, L.H.1    Turner, N.A.2    Bernardo, A.3    Tao, Z.4    Cleary, T.G.5    Dong, J.-F.6    Moake, J.L.7
  • 28
    • 0034648102 scopus 로고    scopus 로고
    • Expression of complement messenger RNAs by human endothelial cells
    • DOI 10.1016/S0006-8993(00)02253-8, PII S0006899300022538
    • Klegeris A., Bissonnette C. J., Dorovini-Zis K., McGeer P. L. Expression of complement messenger RNAs by human endothelial cells. Brain Res: 2000; 871 1 1 6 (Pubitemid 30406861)
    • (2000) Brain Research , vol.871 , Issue.1 , pp. 1-6
    • Klegeris, A.1    Bissonnette, C.J.2    Dorovini-Zis, K.3    McGeer, P.L.4
  • 29
    • 0035076705 scopus 로고    scopus 로고
    • Detection of mRNA for the terminal complement components C5, C6, C8 and C9 in human umbilical vein endothelial cells in vitro
    • Langeggen H., Berge K. E., Macor P., et al. Detection of mRNA for the terminal complement components C5, C6, C8 and C9 in human umbilical vein endothelial cells in vitro. APMIS: 2001; 109 1 73 78 (Pubitemid 32243476)
    • (2001) APMIS , vol.109 , Issue.1 , pp. 73-78
    • Langeggen, H.1    Berg, K.E.2    Macor, P.3    Fischetti, F.4    Tedesco, F.5    Hetland, G.6    Berg, K.7    Johnson, E.8
  • 30
    • 0033945557 scopus 로고    scopus 로고
    • The endothelium is an extrahepatic site of synthesis of the seventh component of the complement system
    • DOI 10.1046/j.1365-2249.2000.01238.x
    • Langeggen H., Pausa M., Johnson E., Casarsa C., Tedesco F. The endothelium is an extrahepatic site of synthesis of the seventh component of the complement system. Clin Exp Immunol: 2000; 121 1 69 76 (Pubitemid 30436017)
    • (2000) Clinical and Experimental Immunology , vol.121 , Issue.1 , pp. 69-76
    • Langeggen, H.1    Pausa, M.2    Johnson, E.3    Casarsa, C.4    Tedesco, F.5
  • 31
    • 0028350821 scopus 로고
    • Complement component C7: Assessment of in vivo synthesis after liver transplantation reveals that hepatocytes do not synthesize the majority of human C7
    • Würzner R., Joysey V. C., Lachmann P. J. Complement component C7. Assessment of in vivo synthesis after liver transplantation reveals that hepatocytes do not synthesize the majority of human C7. J Immunol: 1994; 152 9 4624 4629 (Pubitemid 24134423)
    • (1994) Journal of Immunology , vol.152 , Issue.9 , pp. 4624-4629
    • Wurzner, R.1    Joysey, V.C.2    Lachmann, P.J.3
  • 33
    • 0024386370 scopus 로고
    • Complement proteins C5b-9 induce secretion of high molecular weight multimers of endothelial von Willebrand factor and translocation of granule membrane protein GMP-140 to the cell surface
    • Hattori R., Hamilton K. K., McEver R. P., Sims P. J. Complement proteins C5b-9 induce secretion of high molecular weight multimers of endothelial von Willebrand factor and translocation of granule membrane protein GMP-140 to the cell surface. J Biol Chem: 1989; 264 15 9053 9060 (Pubitemid 19151636)
    • (1989) Journal of Biological Chemistry , vol.264 , Issue.15 , pp. 9053-9060
    • Hattori, R.1    Hamilton, K.K.2    McEver, R.P.3    Sims, P.J.4
  • 34
    • 84860474599 scopus 로고    scopus 로고
    • Complement activation in thrombotic thrombocytopenic purpura
    • Réti M., Farkas P., Csuka D., et al. Complement activation in thrombotic thrombocytopenic purpura. J Thromb Haemost: 2012; 10 5 791 798
    • (2012) J Thromb Haemost , vol.10 , Issue.5 , pp. 791-798
    • Réti, M.1    Farkas, P.2    Csuka, D.3
  • 36
    • 84861526957 scopus 로고    scopus 로고
    • Eculizumab in the treatment of refractory idiopathic thrombotic thrombocytopenic purpura
    • Chapin J., Weksler B., Magro C., Laurence J. Eculizumab in the treatment of refractory idiopathic thrombotic thrombocytopenic purpura. Br J Haematol: 2012; 157 6 772 774
    • (2012) Br J Haematol , vol.157 , Issue.6 , pp. 772-774
    • Chapin, J.1    Weksler, B.2    Magro, C.3    Laurence, J.4
  • 37
    • 84880700770 scopus 로고    scopus 로고
    • Use of eculizumab in the treatment of a case of refractory, ADAMTS13-deficient thrombotic thrombocytopenic purpura: Additional data and clinical follow-up
    • Tsai E., Chapin J., Laurence J. C., Tsai H. M. Use of eculizumab in the treatment of a case of refractory, ADAMTS13-deficient thrombotic thrombocytopenic purpura: additional data and clinical follow-up. Br J Haematol: 2013; 162 4 558 559
    • (2013) Br J Haematol , vol.162 , Issue.4 , pp. 558-559
    • Tsai, E.1    Chapin, J.2    Laurence, J.C.3    Tsai, H.M.4
  • 38
    • 84886851977 scopus 로고    scopus 로고
    • Partial ADAMTS13 deficiency in atypical hemolytic uremic syndrome
    • Feng S., Eyler S. J., Zhang Y., et al. Partial ADAMTS13 deficiency in atypical hemolytic uremic syndrome. Blood: 2013; 122 8 1487 1493
    • (2013) Blood , vol.122 , Issue.8 , pp. 1487-1493
    • Feng, S.1    Eyler, S.J.2    Zhang, Y.3
  • 39
    • 84856863401 scopus 로고    scopus 로고
    • A novel C3 mutation causing increased formation of the C3 convertase in familial atypical hemolytic uremic syndrome
    • Sartz L., Olin A. I., Kristoffersson A. C., et al. A novel C3 mutation causing increased formation of the C3 convertase in familial atypical hemolytic uremic syndrome. J Immunol: 2012; 188 4 2030 2037
    • (2012) J Immunol , vol.188 , Issue.4 , pp. 2030-2037
    • Sartz, L.1    Olin, A.I.2    Kristoffersson, A.C.3
  • 40
    • 67651166873 scopus 로고    scopus 로고
    • Thrombomodulin mutations in atypical hemolytic-uremic syndrome
    • Delvaeye M., Noris M., De Vriese A., et al. Thrombomodulin mutations in atypical hemolytic-uremic syndrome. N Engl J Med: 2009; 361 4 345 357
    • (2009) N Engl J Med , vol.361 , Issue.4 , pp. 345-357
    • Delvaeye, M.1    Noris, M.2    De Vriese, A.3
  • 41
    • 0029871217 scopus 로고    scopus 로고
    • Molecular basis of the heterogeneity of expression of glycosyl phosphatidylinositol anchored proteins in paroxysmal nocturnal hemoglobinuria
    • Endo M., Ware R. E., Vreeke T. M., et al. Molecular basis of the heterogeneity of expression of glycosyl phosphatidylinositol anchored proteins in paroxysmal nocturnal hemoglobinuria. Blood: 1996; 87 6 2546 2557 (Pubitemid 26086901)
    • (1996) Blood , vol.87 , Issue.6 , pp. 2546-2557
    • Endo, M.1    Ware, R.E.2    Vreeke, T.M.3    Singh, S.P.4    Howard, T.A.5    Tomita, A.6    Holguin, M.H.7    Parker, C.J.8
  • 42
    • 0024411828 scopus 로고
    • Isolation and characterization of a membrane protein from normal human erythrocytes that inhibits reactive lysis of the erythrocytes of paroxysmal nocturnal hemoglobinuria
    • Holguin M. H., Fredrick L. R., Bernshaw N. J., Wilcox L. A., Parker C. J. Isolation and characterization of a membrane protein from normal human erythrocytes that inhibits reactive lysis of the erythrocytes of paroxysmal nocturnal hemoglobinuria. J Clin Invest: 1989; 84 1 7 17 (Pubitemid 19170089)
    • (1989) Journal of Clinical Investigation , vol.84 , Issue.1 , pp. 7-17
    • Holguin, M.H.1    Fredrick, L.R.2    Bernshaw, N.J.3    Wilcox, L.A.4    Parker, C.J.5
  • 44
    • 57549087389 scopus 로고    scopus 로고
    • Glycosylphosphatidylinositol-anchored protein deficiency confers resistance to apoptosis in PNH
    • Savage W. J., Barber J. P., Mukhina G. L., et al. Glycosylphosphatidylinositol-anchored protein deficiency confers resistance to apoptosis in PNH. Exp Hematol: 2009; 37 1 42 51
    • (2009) Exp Hematol , vol.37 , Issue.1 , pp. 42-51
    • Savage, W.J.1    Barber, J.P.2    Mukhina, G.L.3
  • 45
    • 0025233715 scopus 로고
    • The complement-inhibitory activity of CD59 resides in its capacity to block incorporation of C9 into membrane C5b-9
    • Rollins S. A., Sims P. J. The complement-inhibitory activity of CD59 resides in its capacity to block incorporation of C9 into membrane C5b-9. J Immunol: 1990; 144 9 3478 3483 (Pubitemid 20146382)
    • (1990) Journal of Immunology , vol.144 , Issue.9 , pp. 3478-3483
    • Rollins, S.A.1    Sims, P.J.2
  • 47
    • 0024806255 scopus 로고
    • Functional properties of membrane cofactor protein of complement
    • Seya T., Atkinson J. P. Functional properties of membrane cofactor protein of complement. Biochem J: 1989; 264 2 581 588 (Pubitemid 20024531)
    • (1989) Biochemical Journal , vol.264 , Issue.2 , pp. 581-588
    • Seya, T.1    Atkinson, J.P.2
  • 48
    • 84882343523 scopus 로고    scopus 로고
    • Thrombosis in paroxysmal nocturnal hemoglobinuria
    • quiz 5105
    • Hill A., Kelly R. J., Hillmen P. Thrombosis in paroxysmal nocturnal hemoglobinuria. Blood: 2013; 121 25 4985 4996, quiz 5105
    • (2013) Blood , vol.121 , Issue.25 , pp. 4985-4996
    • Hill, A.1    Kelly, R.J.2    Hillmen, P.3
  • 49
    • 11244281582 scopus 로고    scopus 로고
    • Fatal congenital thrombotic thrombocytopenic purpura with apparent ADAMTS13 inhibitor: In vitro inhibition of ADAMTS13 activity by hemoglobin
    • DOI 10.1182/blood-2004-06-2096
    • Studt J. D., Kremer Hovinga J. A., Antoine G., et al. Fatal congenital thrombotic thrombocytopenic purpura with apparent ADAMTS13 inhibitor: in vitro inhibition of ADAMTS13 activity by hemoglobin. Blood: 2005; 105 2 542 544 (Pubitemid 40070733)
    • (2005) Blood , vol.105 , Issue.2 , pp. 542-544
    • Studt, J.-D.1    Kremer Hovinga, J.A.2    Antoine, G.3    Hermann, M.4    Rieger, M.5    Scheiflinger, F.6    Lammle, B.7
  • 50
    • 84880923632 scopus 로고    scopus 로고
    • Complement activation by heme as a secondary hit for atypical hemolytic uremic syndrome
    • Frimat M., Tabarin F., Dimitrov J. D., et al. Complement activation by heme as a secondary hit for atypical hemolytic uremic syndrome. Blood: 2013; 122 2 282 292
    • (2013) Blood , vol.122 , Issue.2 , pp. 282-292
    • Frimat, M.1    Tabarin, F.2    Dimitrov, J.D.3
  • 52
    • 73949121978 scopus 로고    scopus 로고
    • Endothelial cell ADAMTS-13 and VWF: Production, release, and VWF string cleavage
    • Turner N. A., Nolasco L., Ruggeri Z. M., Moake J. L. Endothelial cell ADAMTS-13 and VWF: production, release, and VWF string cleavage. Blood: 2009; 114 24 5102 5111
    • (2009) Blood , vol.114 , Issue.24 , pp. 5102-5111
    • Turner, N.A.1    Nolasco, L.2    Ruggeri, Z.M.3    Moake, J.L.4
  • 53
    • 0022852282 scopus 로고
    • Involvement of large plasma von Willebrand Factor (vWF) multimers and unusually large vWF forms derived from endothelial cells in shear stress-induced platelet aggregation
    • Moake J. L., Turner N. A., Stathopoulos N. A., Nolasco L. H., Hellums J. D. Involvement of large plasma von Willebrand factor (vWF) multimers and unusually large vWF forms derived from endothelial cells in shear stress-induced platelet aggregation. J Clin Invest: 1986; 78 6 1456 1461 (Pubitemid 17219507)
    • (1986) Journal of Clinical Investigation , vol.78 , Issue.6 , pp. 1456-1461
    • Moake, J.L.1    Turner, N.A.2    Stathopoulos, N.A.3
  • 54
    • 0029878123 scopus 로고    scopus 로고
    • Physiologic cleavage of von Willebrand factor by a plasma protease is dependent on its conformation and requires calcium ion
    • Tsai H. M. Physiologic cleavage of von Willebrand factor by a plasma protease is dependent on its conformation and requires calcium ion. Blood: 1996; 87 10 4235 4244
    • (1996) Blood , vol.87 , Issue.10 , pp. 4235-4244
    • Tsai, H.M.1
  • 55
    • 0028266474 scopus 로고
    • Shear stress enhances the proteolysis of von Willebrand factor in normal plasma
    • Tsai H. M., Sussman I. I., Nagel R. L. Shear stress enhances the proteolysis of von Willebrand factor in normal plasma. Blood: 1994; 83 8 2171 2179 (Pubitemid 24112728)
    • (1994) Blood , vol.83 , Issue.8 , pp. 2171-2179
    • Tsai, H.-M.1    Sussman, I.I.2    Nagel, R.L.3
  • 56
    • 0023875503 scopus 로고
    • The complete amino acid sequence of human complement factor H
    • Ripoche J., Day A. J., Harris T. J., Sim R. B. The complete amino acid sequence of human complement factor H. Biochem J: 1988; 249 2 593 602 (Pubitemid 18030952)
    • (1988) Biochemical Journal , vol.249 , Issue.2 , pp. 593-602
    • Ripoche, J.1    Day, A.J.2    Harris, T.J.R.3    Sim, R.B.4


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