Therapeutic plasma exchange as rescue therapy in severe sepsis and septic shock: Retrospective observational single-centre study of 23 patients

BMC Anesthesiology

Volumn 14, Issue , 2014, Pages

  Hadem, Johannes ^a   Hafer, Carsten ^a   Schneider, Andrea S ^a   Wiesner, Olaf ^a   Beutel, Gernot ^a   Fuehner, Thomas ^a   Welte, Tobias ^a   Hoeper, Marius M ^a   Kielstein, Jan T ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Apheresis; Multiorgan dysfunction syndrome; Multiple organ failure; Plasmapheresis; Streptococcal toxic shock syndrome

Indexed keywords

FRESH FROZEN PLASMA; NORADRENALIN; PROCALCITONIN;

ADULT; ARTICLE; CLINICAL ARTICLE; DISEASE MARKER; DISEASE SEVERITY; FEMALE; FLUID BALANCE; HEART INDEX; HUMAN; MALE; MULTIPLE ORGAN FAILURE; OBSERVATIONAL STUDY; ORGAN SYSTEMS; PLASMA VOLUME; PLASMAPHERESIS; RETROSPECTIVE STUDY; SEPSIS; SEPTIC SHOCK; SURVIVAL RATE; THROMBOCYTE COUNT; BLOOD; MIDDLE AGED; PROCEDURES; SHOCK, SEPTIC; TREATMENT OUTCOME; TRENDS;

ADULT; FEMALE; HUMANS; MALE; MIDDLE AGED; PLASMA EXCHANGE; PLATELET COUNT; RETROSPECTIVE STUDIES; SEPSIS; SHOCK, SEPTIC; TREATMENT OUTCOME;

EID: 84899490932     PISSN: None     EISSN: 14712253     Source Type: Journal    
DOI: 10.1186/1471-2253-14-24     Document Type: Article

References (44)

1. Bernard GR, Vincent JL, Laterre PF, LaRosa SP, Dhainaut JF, Lopez-Rodriguez A, Steingrub JS, Garber GE, Helterbrand JD, Ely EW, Fisher CJ., Recombinant human protein C Worldwide Evaluation in Severe Sepsis (PROWESS) study group Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 2001, 344:699-709. 10.1056/NEJM200103083441001, 11236773, Recombinant human protein C Worldwide Evaluation in Severe Sepsis (PROWESS) study group.
2. Annane D, Aegerter P, Jars-Guincestre MC, Guidet B. Current epidemiology of septic shock: the CUB-Rea network. Am J Respir Crit Care Med 2003, 168:165-72. 10.1164/rccm.2201087, 12851245.
3. Russell JA. Management of sepsis. N Engl J Med 2006, 355:1699-713. 10.1056/NEJMra043632, 17050894.
4. Klempner MS, Talbot EA, Lee SI, Zaki S, Ferraro MJ. A 24-year-old woman with abdominal pain and shock. N Engl J Med 2010, 363:766-77. 10.1056/NEJMcpc1003887, 20818879.
5. Gustot T, Durand F, Lebrec D, Vincent JL, Moreau R. Severe sepsis in cirrhosis. Hepatology 2009, 20:2022-2033.
6. Weineisen M, Sjöbring U, Fällman M, Andersson T. Streptococcal M5 protein prevents neutrophil phagocytosis by interfering with CD11b/CD18 receptor-mediated association an signalling. J Immunol 2004, 172:3798-807.
7. Bryant AE. Biology and pathogenesis of thrombosis and procoagulant activity in invasive infections caused by group A streptococci and Clostridium perfringens. Clin Microbiol Rev 2003, 16:451-62. 10.1128/CMR.16.3.451-462.2003, 164226, 12857777.
8. Carcillo JA, Kellum JA. Is there a role for plasmapheresis/plasma exchange therapy in septic shock, MODS, and thrombocytopenia-associated multiple organ failure? We still do not know - but perhaps we are closer. Intensive Care Med 2002, 28:1373-1375. 10.1007/s00134-002-1428-x, 12373459.
9. Martin K, Borgel D, Lerolle N, Feys HB, Trinquart L, Vanhoorelbeke K, Deckmyn H, Legendre P, Diehl JL, Baruch D. Decreased ADAMTS-13 (a disintegrin-like and metalloprotease with thrombospondin type 1 repeats) is associated with a poor prognosis in sepsis-induced organ failure. Crit Care Med 2007, 35:2375-82. 10.1097/01.CCM.0000284508.05247.B3, 17944029.
10. Busund R, Koukline V, Utrobin U, Nedashkovsky E. Plasmapheresis in severe sepsis and septic shock: a prospective, randomized, controlled trial. Intensive Care Med 2002, 28:1434-9. 10.1007/s00134-002-1410-7, 12373468.
11. Reeves JH, Butt WW, Shann F, Layton JE, Stewart A, Waring PM, Presneill JJ. Continuous plasma filtration in sepsis syndrome. Plasmafiltration in sepsis study group. Crit Care Med 1999, 27:2096-104. 10.1097/00003246-199910000-00003, 10548188.
12. Scharfman WB, Tillotson JR, Taft GE, Wright E. Plasmapheresis for meningococcemia with disseminated intravascular coagulation. N Engl J Med 1979, 300:1277-1278.
13. Barzilay E, Kessler D, Berlot G, Gullo A, Geber D, Ben Zeev I. Use of extracorporeal supportive techniques as additional treatment for septic-induced multiple organ failure patients. Crit Care Med 1989, 17:634-637. 10.1097/00003246-198907000-00007, 2736923.
14. Van Deuren M, Santman FW, van Dalen R, Sauerwein RW, Span LFR, van der Meer JWM. Plasma and whole blood exchange in meningococcal sepsis. Clin Infect Dis 1992, 15:424-430. 10.1093/clind/15.3.424, 1520788.
15. Gardlund B, Sjolin J, Nilsson A, Roll M, Wickerts CJ, Wilkström B, Wretlind B. Plasmapheresis in the treatment of primary septic shock in humans. Scand J Infect Dis 1993, 25:757-61. 10.3109/00365549309008575, 8052817.
16. Stegmayr BG. Plasma exchange in patients with septic shock including acute renal failure. Blood Purif 1996, 14:102-8. 10.1159/000170251, 8718573.
17. Berlot G, Gullo A, Fasiolo S, Serra L, Silvestri L, Worz M. Hemodynamic effects of plasma exchange in septic patients: preliminary report. Blood Purif 1997, 15:45-53. 10.1159/000170316, 9096906.
18. Simmonds M. Necrotising fasciitis and group A streptococcus toxic shock-like syndrome in pregnancy: treatment with plasmapheresis and immunoglobulin. Int J Obstet Anesth 1999, 8:125-30. 10.1016/S0959-289X(99)80009-0, 15321156.
19. Hjorth V, Stenlund G. Plasmapheresis as part of the treatment for septic shock. Scand J Infect Dis 2000, 32:511-4. 10.1080/003655400458794, 11055656.
20. Schmidt J, Mann S, Mohr VD, Lampert R, Firla U, Zirngibl H. Plasmapheresis combined with continuous venovenous hemofiltration in surgical patients with sepsis. Intensive Care Med 2000, 26:532-7. 10.1007/s001340051200, 10923726.
21. Hoeper MM, Abou-Rebyeh F, Athman C, Schwarz A. Plasmapheresis in streptococcal toxic shock syndrome. Crit Care Med 2001, 29:2399. 10.1097/00003246-200112000-00033, 11801855.
22. Ronco C, Brendolan A, Lonnemann G, Bellomo R, Piccinni P, Digito A. A pilot study of coupled plasma filtration with adsorption in septic shock. Crit Care Med 2002, 30:1250-1255. 10.1097/00003246-200206000-00015, 12072677.
23. Ataman K, Jehmlich M, Kock S, Neumann S, Leischik M, Filipovic Z, Hopf HB. Short-term cardiovascular effects of plasmapheresis in norepinephrine-refractory septic shock. Intensive Care Med 2002, 28:1164-1167. 10.1007/s00134-002-1375-6, 12185443.
24. Stegmayr BG, Banga R, Gerggren L, Norda R, Rydvall A, Vikerfors T. Plasma exchange as rescue therapy in multiple organ failure including acute renal failure. Crit Care Med 2003, 31:1730-6. 10.1097/01.CCM.0000064742.00981.14, 12794412.
25. Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb SA, Beale RJ, Vincent JL, Moreno R., Surviving Sepsis Campaign International Guidelines for Management of Severe Sepsis and Septic Shock: 2012. Crit Care Med 2013, 41:580-637. 10.1097/CCM.0b013e31827e83af, 23353941, Surviving Sepsis Campaign.
26. Bellomo R, Honoré PM, Matson J, Ronco C, Winchester J. Extracorporeal blood treatment (EBT) methods in SIRS/Sepsis. Int J Artif Organs 2005, 28:450-458.
27. Szczepiorkowski ZM, Winters JL, Bandarenko N, Kim HC, Linenberger ML, Marques MB, Sarode R, Schwartz J, Weinstein R, Shaz BH., Apheresis Applications Committee of the American Society for Apheresis Guidelines on the use of therapeutic apheresis in clinical practice - evidence-based approach from the Apheresis Applications Committee of the American Society of Apheresis. J Clin Apher 2010, 25:83-177. 10.1002/jca.20240, 20568098, Apheresis Applications Committee of the American Society for Apheresis.
28. Reinhart K, Brunkhorst FM, Bone HG, Bardutzky J, Dempfle CE, Forst H, Gastmeier P, Gerlach H, Gründling M, John S, Kern W, Kreymann G, Krüger W, Kujath P, Marggraf G, Martin J, Mayer K, Meier-Hellmann A, Oppert M, Putensen C, Quintel M, Ragaller M, Rossaint R, Seifert H, Spies C, Stüber F, Weiler N, Weimann A, Werdan K, Welte T, et al. Prevention, diagnosis, therapy and follow-up care of sepsis: 1st revision of S-2k guidelines of the German Sepsis Society (Deutsche Sepsis-Gesellschaft e.V.) and the German Interdisciplinary Association of Intensive Care and Emergency Medicine (Deutsche Interdisziplinäre Vereinigung für Intensiv- und Notfallmedizin). Ger Med Sci 2010, 28:Doc14.
29. Faulhaber-Walter R, Hafer C, Jahr N, Vahlbruch J, Hoy L, Haller H, Fliser D, Kielstein JT. The Hannover Dialysis Outcome study: comparison of standard versus intensified extended dialysis for treatment of patients with acute kidney injury in the intensive care unit. Nephrol Dial Transplant 2009, 24:2179-86. 10.1093/ndt/gfp035, 19218540.
30. Kaplan AA. A simple and accurate method for prescribing plasma exchange [abstract]. ASAIO Trans 1990, 36:M597.
31. Vincent JL, Moreno R, Takala J, Willatts S, de Medonca A, Bruining H, Reinhart CK, Suter PM, Thijs LG. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med 1996, 22:707-710. 10.1007/BF01709751, 8844239.
32. Vincent JL. We should abandon randomized controlled trials in the intensive care unit. Crit Care Med 2010, 38(Suppl):S534-S538.
33. Kaplan A. Complications of apheresis. Semin Dial 2012, 25:152-158. 10.1111/j.1525-139X.2011.01026.x, 22321209.
34. Madore F. Plasmapheresis - technical aspects and indications. Crit Care Clin 2002, 18:375-92. 10.1016/S0749-0704(01)00010-0, 12053839.
35. Vincent JL, Sakr Y, Sprung CL, Ranieri VM, Reinhart K, Gerlach H, Moreno R, Carlet J, Le Gall J-R, Payen D., on behalf of the Sepsis Occurrence in Acutely Ill Patients Investigators Sepsis in European intensive care units: results of the SOAP study. Crit Care Med 2006, 34:344-353. 10.1097/01.CCM.0000194725.48928.3A, 16424713, on behalf of the Sepsis Occurrence in Acutely Ill Patients Investigators.
36. Annane D, Vignon P, Renault A, Bollaert PE, Charpentier C, Martin C. Norepinephrine plus dobutamine versus epinephrine alone for management of septic shock: a randomised trial. Lancet 2007, 370:676-84. 10.1016/S0140-6736(07)61344-0, 17720019.
37. Jones AE, Trzeciak S, Kline JA. The sequential organ failure assessment score for predicting outcome in patients with severe sepsis and evidence of hypoperfusion at the time of emergency department presentation. Crit Care Med 2009, 37:1649-1654. 10.1097/CCM.0b013e31819def97, 2703722, 19325482.
38. Flaum MA, Cuneo RA, Appelbaum FR, Deisseroth AB, Engel WK, Gralnick HR. The hemostatic imbalance of plasma-exchange transfusion. Blood 1979, 54:694-702.
39. Stegmayr B, Abdel-Rahman EM, Balogun RA. Septic shock with multiorgan failure: from conventional apheresis to adsorption therapies. Semin Dial 2012, 25:171-175. 10.1111/j.1525-139X.2011.01029.x, 22329732.
40. Fülöp T, Pathak MB, Schmidt DW, Lengvárszky Z, Juncos JP, Lebrun CJ, Brar H, Juncos LA. Volume-related weight gain and subsequent mortality in acute renal failure patients treated with continuous renal replacement therapy. ASAIO J 2010, 56:333-7. 2895683, 20559136.
41. Teixeira C, Garzotto F, Piccinni P, Brienza N, Iannuzzi M, Gramaticopolo S, Forfori F, Pelaia P, Rocco M, Ronco C, Anello CB, Bove T, Carlini M, Michetti V, Cruz DN., or the NEFROlogia e Cura INTensiva (NEFROINT) investigators Fluid balance and urine volume are independent predictors of mortality in acute kidney injury. Crit Care 2013, 17:R14. 10.1186/cc12484, 23347825, or the NEFROlogia e Cura INTensiva (NEFROINT) investigators.
42. David S, Mukherjee A, Ghosh CC, Yano M, Khankin EV, Wenger JB, Karumanchi SA, Shapiro NI, Parikh SM. Angiopoietin-2 may contribute to multiple organ dysfunction and death in sepsis. Crit Care Med 2012, 40:3034-41. 10.1097/CCM.0b013e31825fdc31, 3705559, 22890252.
43. Lovric S, Lukasz A, Hafer C, Kielstein JT, Haubitz M, Haller H, Kümpers P. Removal of elevated circulating angiopoietipn-2 by plasma exchange - a pilot study in critically ill patients with thrombotic microangiopathy and anti-glomerular basement membrane disease. Thromb Haemost 2010, 104:1038-43. 10.1160/TH10-02-0138, 20806109.
44. Stevens DL, Tanner MH, Winship J, Swarts R, Ries KM, Schlievert PM, Kaplan E. Severe group A streptococcal infections associated with a toxic shock-like syndrome and scarlet fever toxin A. N Engl J Med 1989, 321:1-7. 10.1056/NEJM198907063210101, 2659990.