The balance between von-Willebrand factor and its cleaving protease ADAMTS13: Biomarker in systemic inflammation and development of organ failure?

Current Molecular Medicine

Volumn 10, Issue 2, 2010, Pages 236-248

  Claus, R A ^a   Bockmeyer, C L ^a,b   Sossdorf, M ^a   Losche W ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

ADAMTS13; Organ failure; Platelets; Sepsis; Systemic inflammation; Thrombotic microangiopathy; Von Willebrand factor

Indexed keywords

BIOLOGICAL MARKER; POLYMER; THROMBOPLASTIN; THROMBOSPONDIN; THROMBOSPONDIN 1; VON WILLEBRAND FACTOR; VON WILLEBRAND FACTOR CLEAVING PROTEINASE;

CELL ACTIVATION; DISSEMINATED INTRAVASCULAR CLOTTING; ENDOTHELIUM CELL; ENZYME ACTIVITY; GENETIC TRANSCRIPTION; HUMAN; LIVER VENOOCCLUSIVE DISEASE; MOLECULAR CLONING; MULTIPLE ORGAN FAILURE; PHENOTYPE; PROGNOSIS; PROTEIN DEGRADATION; REVIEW; SEPSIS; SHEAR STRESS; STEM CELL TRANSPLANTATION; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; THROMBOCYTE ACTIVATION; THROMBOCYTOPENIA; THROMBOTIC THROMBOCYTOPENIC PURPURA;

ADAM PROTEINS; ANIMALS; BIOLOGICAL MARKERS; BLOOD PLATELETS; HUMANS; INFLAMMATION; MICE; MODELS, BIOLOGICAL; MULTIPLE ORGAN FAILURE; PHENOTYPE; PLATELET ACTIVATION; PROGNOSIS; SEPSIS;

EID: 77951034286     PISSN: 15665240     EISSN: None     Source Type: Journal    
DOI: 10.2174/156652410790963367     Document Type: Review

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