메뉴 건너뛰기




Volumn 18, Issue 8, 2015, Pages 1-12

Increased contextual fear conditioning in inos knockout mice: Additional evidence for the involvement of nitric oxide in stress-related disorders and contribution of the endocannabinoid system

Author keywords

7 nitroindazole; AM281; anandamide; CB1 receptors; extinction; fear conditioning; nitric oxide; URB597; WIN55,212 2

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N MORPHOLINO 1H PYRAZOLE 3 CARBOXAMIDE; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 7 NITROINDAZOLE; ANANDAMIDE; CANNABINOID 1 RECEPTOR ANTAGONIST; CANNABINOID RECEPTOR AGONIST; CYCLOHEXYLCARBAMIC ACID 3' CARBAMOYLBIPHENYL 3 YL ESTER; ENDOCANNABINOID; FATTY ACID AMIDASE INHIBITOR; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; 7-NITROINDAZOLE; AMIDE; ARACHIDONIC ACID DERIVATIVE; BENZAMIDE DERIVATIVE; BENZOXAZINE DERIVATIVE; CANNABINOID 1 RECEPTOR; CANNABINOID RECEPTOR ANTAGONIST; CARBAMIC ACID DERIVATIVE; CYCLOHEXYL CARBAMIC ACID 3'-CARBAMOYLBIPHENYL-3-YL ESTER; ENZYME INHIBITOR; INDAZOLE DERIVATIVE; MORPHOLINE DERIVATIVE; NAPHTHALENE DERIVATIVE; NOS2 PROTEIN, MOUSE; PYRAZOLE DERIVATIVE;

EID: 84931269309     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1093/ijnp/pyv005     Document Type: Article
Times cited : (36)

References (103)
  • 1
    • 52949148570 scopus 로고    scopus 로고
    • Enhanced stress reactivity in nitric oxide synthase type 2 mutant mice: Findings in support of astrocytic nitrosative modulation of behavior
    • Abu-Ghanem Y, Cohen H, Buskila Y, Grauer E, Amitai Y (2008) Enhanced stress reactivity in nitric oxide synthase type 2 mutant mice: findings in support of astrocytic nitrosative modulation of behavior. Neuroscience 156:257-265
    • (2008) Neuroscience , vol.156 , pp. 257-265
    • Abu-Ghanem, Y.1    Cohen, H.2    Buskila, Y.3    Grauer, E.4    Amitai, Y.5
  • 2
    • 70349243813 scopus 로고    scopus 로고
    • Blockade of NMDA receptors and nitric oxide synthesis in the dorsolateral periaqueductal gray attenuates behavioral and cellular responses of rats exposed to a live predator
    • Aguiar DC, Guimaraes FS (2009) Blockade of NMDA receptors and nitric oxide synthesis in the dorsolateral periaqueductal gray attenuates behavioral and cellular responses of rats exposed to a live predator. J Neurosci Res 87:2418-2429
    • (2009) J Neurosci Res , vol.87 , pp. 2418-2429
    • Aguiar, D.C.1    Guimaraes, F.S.2
  • 3
    • 78649353334 scopus 로고    scopus 로고
    • Physiologic role forinducible nitric oxide synthase: A new form of astrocytic-neuronal interface
    • Amitai Y (2010) Physiologic role for "inducible" nitric oxide synthase: a new form of astrocytic-neuronal interface. Glia 58:1775-1781
    • (2010) Glia , vol.58 , pp. 1775-1781
    • Amitai, Y.1
  • 4
    • 71249145400 scopus 로고    scopus 로고
    • Genetics of PTSD: Fear conditioning as a model for future research
    • Amstadter AB, Nugent NR, Koenen KC (2009) Genetics of PTSD: Fear conditioning as a model for future research. Psychiatr Ann 39:358-367
    • (2009) Psychiatr Ann , vol.39 , pp. 358-367
    • Amstadter, A.B.1    Nugent, N.R.2    Koenen, K.C.3
  • 6
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal biochem 72:248-254
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 7
    • 0030912711 scopus 로고    scopus 로고
    • Regulation of inducible nitric oxide synthase expression in human glia: Implications for inflammatory central nervous system diseases
    • Brosnan CF, Lee SC, Liu J (1997) Regulation of inducible nitric oxide synthase expression in human glia: implications for inflammatory central nervous system diseases. Biochem Soc Trans 25:679-683
    • (1997) Biochem Soc Trans , vol.25 , pp. 679-683
    • Brosnan, C.F.1    Lee, S.C.2    Liu, J.3
  • 8
    • 41049110413 scopus 로고    scopus 로고
    • Enhanced astrocytic nitric oxide production and neuronal modifications in the neocortex of a NOS2 mutant mouse
    • Buskila Y, Abu-Ghanem Y, Levi Y, Moran A, Grauer E, Amitai Y (2007) Enhanced astrocytic nitric oxide production and neuronal modifications in the neocortex of a NOS2 mutant mouse. PloS one 2:e843
    • (2007) PloS One , vol.2 , pp. e843
    • Buskila, Y.1    Abu-Ghanem, Y.2    Levi, Y.3    Moran, A.4    Grauer, E.5    Amitai, Y.6
  • 10
    • 79953662385 scopus 로고    scopus 로고
    • Immune system to brain signaling: Neuropsychopharmacological implications
    • Capuron L, Miller AH (2011) Immune system to brain signaling: neuropsychopharmacological implications. Pharmacol Ther 130:226-238
    • (2011) Pharmacol Ther , vol.130 , pp. 226-238
    • Capuron, L.1    Miller, A.H.2
  • 11
    • 0034103659 scopus 로고    scopus 로고
    • Roles of NMDA receptor activity and nitric oxide production in brain development
    • Contestabile A (2000) Roles of NMDA receptor activity and nitric oxide production in brain development. Brain Res Brain Res Rev 32:476-509
    • (2000) Brain Res Brain Res Rev , vol.32 , pp. 476-509
    • Contestabile, A.1
  • 12
    • 0031975261 scopus 로고    scopus 로고
    • Antiinflammatory effects of mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, in carrageenan-induced models of inflammation
    • Cuzzocrea S, Zingarelli B, Hake P, Salzman AL, Szabo C (1998) Antiinflammatory effects of mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, in carrageenan-induced models of inflammation. Free Radic Biol Med 24:450-459
    • (1998) Free Radic Biol Med , vol.24 , pp. 450-459
    • Cuzzocrea, S.1    Zingarelli, B.2    Hake, P.3    Salzman, A.L.4    Szabo, C.5
  • 14
    • 1842611887 scopus 로고    scopus 로고
    • The endocannabinoid system: A general view and latest additions
    • De Petrocellis L, Cascio MG, Di Marzo V (2004) The endocannabinoid system: a general view and latest additions. Br J Pharmacol 141:765-774
    • (2004) Br J Pharmacol , vol.141 , pp. 765-774
    • De Petrocellis, L.1    Cascio, M.G.2    Di Marzo, V.3
  • 15
    • 0037499422 scopus 로고    scopus 로고
    • Aged endothelial nitric oxide synthase knockout mice exhibit higher mortality concomitant with impaired open-field habituation and alterations in forebrain neurotransmitter levels
    • Dere E, De Souza Silva MA, Topic B, Fiorillo C, Li JS, Sadile AG, Frisch C, Huston JP (2002) Aged endothelial nitric oxide synthase knockout mice exhibit higher mortality concomitant with impaired open-field habituation and alterations in forebrain neurotransmitter levels. Genes Brain Behav 1:204-213
    • (2002) Genes Brain Behav , vol.1 , pp. 204-213
    • Dere, E.1    De Souza Silva, M.A.2    Topic, B.3    Fiorillo, C.4    Li, J.S.5    Sadile, A.G.6    Frisch, C.7    Huston, J.P.8
  • 16
    • 33947128224 scopus 로고    scopus 로고
    • Endocannabinoids and the regulation of their levels in health and disease
    • Di Marzo V, Petrosino S (2007) Endocannabinoids and the regulation of their levels in health and disease. Curr Opin Lipidol 18:129-140
    • (2007) Curr Opin Lipidol , vol.18 , pp. 129-140
    • Di Marzo, V.1    Petrosino, S.2
  • 17
    • 0028326424 scopus 로고
    • Endothelial nitric oxide synthase localized to hippocampal pyramidal cells: Implications for synaptic plasticity
    • Dinerman JL, Dawson TM, Schell MJ, Snowman A, Snyder SH (1994) Endothelial nitric oxide synthase localized to hippocampal pyramidal cells: implications for synaptic plasticity. Proc Natl Acad Sci U S A 91:4214-4218
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 4214-4218
    • Dinerman, J.L.1    Dawson, T.M.2    Schell, M.J.3    Snowman, A.4    Snyder, S.H.5
  • 18
    • 0036196417 scopus 로고    scopus 로고
    • NO as a signalling molecule in the nervous system
    • Esplugues JV (2002) NO as a signalling molecule in the nervous system. Br J Pharmacol 135:1079-1095
    • (2002) Br J Pharmacol , vol.135 , pp. 1079-1095
    • Esplugues, J.V.1
  • 19
    • 84907981514 scopus 로고    scopus 로고
    • The expression of contextual fear conditioning involves activation of a NMDA receptor-nitric oxide-cGMP pathway in the dorsal hippocampus of rats
    • Fabri DR, Hott SC, Reis DG, Biojone C, Correa FM, Resstel LB (2014) The expression of contextual fear conditioning involves activation of a NMDA receptor-nitric oxide-cGMP pathway in the dorsal hippocampus of rats. Eur Neuropsychopharmacol 24:1676-1686
    • (2014) Eur Neuropsychopharmacol , vol.24 , pp. 1676-1686
    • Fabri, D.R.1    Hott, S.C.2    Reis, D.G.3    Biojone, C.4    Correa, F.M.5    Resstel, L.B.6
  • 22
    • 30544445587 scopus 로고    scopus 로고
    • Anxiolytic-like effects induced by nitric oxide synthase inhibitors microinjected into the medial amygdala of rats
    • Forestiero D, Manfrim CM, Guimaraes FS, de Oliveira RM (2006) Anxiolytic-like effects induced by nitric oxide synthase inhibitors microinjected into the medial amygdala of rats. Psychopharmacology (Berl) 184:166-172
    • (2006) Psychopharmacology (Berl , vol.184 , pp. 166-172
    • Forestiero, D.1    Manfrim, C.M.2    Guimaraes, F.S.3    De Oliveira, R.M.4
  • 23
    • 0034281379 scopus 로고    scopus 로고
    • Superior water maze performance and increase in fear-related behavior in the endothelial nitric oxide synthase- deficient mouse together with monoamine changes in cerebellum and ventral striatum
    • Frisch C, Dere E, Silva MA, Godecke A, Schrader J, Huston JP (2000) Superior water maze performance and increase in fear-related behavior in the endothelial nitric oxide synthase- deficient mouse together with monoamine changes in cerebellum and ventral striatum. J Neurosci 20:6694-6700
    • (2000) J Neurosci , vol.20 , pp. 6694-6700
    • Frisch, C.1    Dere, E.2    Silva, M.A.3    Godecke, A.4    Schrader, J.5    Huston, J.P.6
  • 24
    • 78049356034 scopus 로고    scopus 로고
    • An inducible nitric oxide synthase polymorphism is associated with the risk of recurrent depressive disorder
    • Galecki P, Maes M, Florkowski A, Lewinski A, Galecka E, Bienkiewicz M, Szemraj J (2010) An inducible nitric oxide synthase polymorphism is associated with the risk of recurrent depressive disorder. Neurosci Lett 486:184-187
    • (2010) Neurosci Lett , vol.486 , pp. 184-187
    • Galecki, P.1    Maes, M.2    Florkowski, A.3    Lewinski, A.4    Galecka, E.5    Bienkiewicz, M.6    Szemraj, J.7
  • 25
    • 79851509688 scopus 로고    scopus 로고
    • Association between inducible and neuronal nitric oxide synthase polymorphisms and recurrent depressive disorder
    • Galecki P, Maes M, Florkowski A, Lewinski A, Galecka E, Bienkiewicz M, Szemraj J (2011) Association between inducible and neuronal nitric oxide synthase polymorphisms and recurrent depressive disorder. J Affect Disord 129:175-182
    • (2011) J Affect Disord , vol.129 , pp. 175-182
    • Galecki, P.1    Maes, M.2    Florkowski, A.3    Lewinski, A.4    Galecka, E.5    Bienkiewicz, M.6    Szemraj, J.7
  • 26
    • 45849103124 scopus 로고    scopus 로고
    • Stress as a neuroinflammatory condition in brain: Damaging and protective mechanisms
    • Garcia-Bueno B, Caso JR, Leza JC (2008) Stress as a neuroinflammatory condition in brain: damaging and protective mechanisms. Neurosci Biobehav Rev 32:1136-1151
    • (2008) Neurosci Biobehav Rev , vol.32 , pp. 1136-1151
    • Garcia-Bueno, B.1    Caso, J.R.2    Leza, J.C.3
  • 27
    • 71649090126 scopus 로고    scopus 로고
    • Involvement of NO-cGMP pathway in anti-Anxiety effect of aminoguanidine in stressed mice
    • Gilhotra N, Dhingra D (2009) Involvement of NO-cGMP pathway in anti-Anxiety effect of aminoguanidine in stressed mice. Prog Neuropsychopharmacol Biol Psych 33:1502-1507
    • (2009) Prog Neuropsychopharmacol Biol Psych , vol.33 , pp. 1502-1507
    • Gilhotra, N.1    Dhingra, D.2
  • 28
    • 84865591190 scopus 로고    scopus 로고
    • Correlation between hippocampal levels of neural, epithelial and inducible NOS and spatial learning skills in rats
    • Gokcek-Sarac C, Karakurt S, Adali O, Jakubowska-Dogru E (2012) Correlation between hippocampal levels of neural, epithelial and inducible NOS and spatial learning skills in rats. Behav Brain Res 235:326-333
    • (2012) Behav Brain Res , vol.235 , pp. 326-333
    • Gokcek-Sarac, C.1    Karakurt, S.2    Adali, O.3    Jakubowska-Dogru, E.4
  • 30
    • 58049190133 scopus 로고    scopus 로고
    • Interleukin-1 (IL-1): A central regulator of stress responses
    • Goshen I, Yirmiya R (2009) Interleukin-1 (IL-1): a central regulator of stress responses. Front Neuroendocrinol 30:30-45
    • (2009) Front Neuroendocrinol , vol.30 , pp. 30-45
    • Goshen, I.1    Yirmiya, R.2
  • 32
    • 79952439462 scopus 로고    scopus 로고
    • Cannabinoid receptor activation modifies NMDA receptor mediated release of intracellular calcium: Implications for endocannabinoid control of hippocampal neural plasticity
    • Hampson RE, Miller F, Palchik G, Deadwyler SA (2011) Cannabinoid receptor activation modifies NMDA receptor mediated release of intracellular calcium: implications for endocannabinoid control of hippocampal neural plasticity. Neuropharmacology 60:944-952
    • (2011) Neuropharmacology , vol.60 , pp. 944-952
    • Hampson, R.E.1    Miller, F.2    Palchik, G.3    Deadwyler, S.A.4
  • 33
    • 5444235355 scopus 로고    scopus 로고
    • Stress-restress evokes sustained iNOS activity and altered GABA levels and NMDA receptors in rat hippocampus
    • Harvey BH, Oosthuizen F, Brand L, Wegener G, Stein DJ (2004) Stress-restress evokes sustained iNOS activity and altered GABA levels and NMDA receptors in rat hippocampus. Psychopharmacology (Berl) 175:494-502
    • (2004) Psychopharmacology (Berl , vol.175 , pp. 494-502
    • Harvey, B.H.1    Oosthuizen, F.2    Brand, L.3    Wegener, G.4    Stein, D.J.5
  • 34
    • 0035283321 scopus 로고    scopus 로고
    • Expression and function of inducible nitric oxide synthase in neurons
    • Heneka MT, Feinstein DL (2001) Expression and function of inducible nitric oxide synthase in neurons. J Neuroimmunol 114:8-18
    • (2001) J Neuroimmunol , vol.114 , pp. 8-18
    • Heneka, M.T.1    Feinstein, D.L.2
  • 36
    • 0029677230 scopus 로고    scopus 로고
    • 7-Nitro indazole, a selective neuronal nitric oxide synthase inhibitor in vivo, impairs spatial learning in the rat
    • Holscher C, McGlinchey L, Anwyl R, Rowan MJ (1996) 7-Nitro indazole, a selective neuronal nitric oxide synthase inhibitor in vivo, impairs spatial learning in the rat. Learn Mem 2:267-278
    • (1996) Learn Mem , vol.2 , pp. 267-278
    • Holscher, C.1    McGlinchey, L.2    Anwyl, R.3    Rowan, M.J.4
  • 38
    • 33645103130 scopus 로고    scopus 로고
    • Inhibition of neuronal nitric oxide synthase in the rat hippocampus induces antidepressantlike effects
    • Joca SR, Guimaraes FS (2006) Inhibition of neuronal nitric oxide synthase in the rat hippocampus induces antidepressantlike effects. Psychopharmacology (Berl) 185:298-305
    • (2006) Psychopharmacology (Berl , vol.185 , pp. 298-305
    • Joca, S.R.1    Guimaraes, F.S.2
  • 41
    • 77955573506 scopus 로고    scopus 로고
    • Pharmacological modulators of nitric oxide signaling and contextual fear conditioning in mice
    • Kelley JB, Anderson KL, Itzhak Y (2010) Pharmacological modulators of nitric oxide signaling and contextual fear conditioning in mice. Psychopharmacology (Berl) 210:65-74
    • (2010) Psychopharmacology (Berl , vol.210 , pp. 65-74
    • Kelley, J.B.1    Anderson, K.L.2    Itzhak, Y.3
  • 42
    • 66349136893 scopus 로고    scopus 로고
    • Impairments in fear conditioning in mice lacking the nNOS gene
    • Kelley JB, Balda MA, Anderson KL, Itzhak Y (2009) Impairments in fear conditioning in mice lacking the nNOS gene. Learn Mem 16:371-378
    • (2009) Learn Mem , vol.16 , pp. 371-378
    • Kelley, J.B.1    Balda, M.A.2    Anderson, K.L.3    Itzhak, Y.4
  • 45
    • 35649020711 scopus 로고    scopus 로고
    • The endocannabinoid system in the processing of anxiety and fear and how CB1 receptors may modulate fear extinction
    • Lafenetre P, Chaouloff F, Marsicano G (2007) The endocannabinoid system in the processing of anxiety and fear and how CB1 receptors may modulate fear extinction. Pharmacol Res 56:367-381
    • (2007) Pharmacol Res , vol.56 , pp. 367-381
    • Lafenetre, P.1    Chaouloff, F.2    Marsicano, G.3
  • 48
    • 84921974642 scopus 로고    scopus 로고
    • Anxiety-behavior modulated by ventral medial prefrontal cortex of rats submitted to the vogel conflict test involves a local NMDA receptor and nitric oxide
    • Lisboa SF, Guimaras FS, Resstel LBM (2011) Anxiety-behavior modulated by ventral medial prefrontal cortex of rats submitted to the vogel conflict test involves a local NMDA receptor and nitric oxide. J Behav Brain Sci 1:181-187
    • (2011) J Behav Brain Sci , vol.1 , pp. 181-187
    • Lisboa, S.F.1    Guimaras, F.S.2    Lbm, R.3
  • 49
    • 84859700547 scopus 로고    scopus 로고
    • Differential role of CB1 and TRPV1 receptors on anandamide modulation of defensive responses induced by nitric oxide in the dorsolateral periaqueductal gray
    • Lisboa SF, Guimaraes FS (2012) Differential role of CB1 and TRPV1 receptors on anandamide modulation of defensive responses induced by nitric oxide in the dorsolateral periaqueductal gray. Neuropharmacology 62:2455-2462
    • (2012) Neuropharmacology , vol.62 , pp. 2455-2462
    • Lisboa, S.F.1    Guimaraes, F.S.2
  • 50
    • 84883006112 scopus 로고    scopus 로고
    • Complex interaction between anandamide and the nitrergic system in the dorsolateral periaqueductal gray to modulate anxiety-like behavior in rats
    • Lisboa SF, Magesto AC, Aguiar JC, Resstel LB, Guimaraes FS (2013) Complex interaction between anandamide and the nitrergic system in the dorsolateral periaqueductal gray to modulate anxiety-like behavior in rats. Neuropharmacology 75C:86-94
    • (2013) Neuropharmacology , vol.75 , pp. 86-94
    • Lisboa, S.F.1    Magesto, A.C.2    Aguiar, J.C.3    Resstel, L.B.4    Guimaraes, F.S.5
  • 52
    • 34047139505 scopus 로고    scopus 로고
    • The endocannabinoid pathway in Huntington's disease: A comparison with other neurodegenerative diseases
    • Maccarrone M, Battista N, Centonze D (2007) The endocannabinoid pathway in Huntington's disease: a comparison with other neurodegenerative diseases. Prog Neurobiol 81:349-379
    • (2007) Prog Neurobiol , vol.81 , pp. 349-379
    • Maccarrone, M.1    Battista, N.2    Centonze, D.3
  • 53
    • 79954604454 scopus 로고    scopus 로고
    • The new '5-HT' hypothesis of depression: Cell-mediated immune activation induces indoleamine 2, 3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression
    • Maes M, Leonard BE, Myint AM, Kubera M, Verkerk R (2011) The new '5-HT' hypothesis of depression: cell-mediated immune activation induces indoleamine 2, 3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression. Prog Neuropsychopharmacol Biol Psych 35:702-721
    • (2011) Prog Neuropsychopharmacol Biol Psych , vol.35 , pp. 702-721
    • Maes, M.1    Leonard, B.E.2    Myint, A.M.3    Kubera, M.4    Verkerk, R.5
  • 54
    • 82655172359 scopus 로고    scopus 로고
    • Activation of cell-mediated immunity in depression: Association with inflammation, melancholia, clinical staging and the fatigue and somatic symptom cluster of depression
    • Maes M, Mihaylova I, Kubera M, Ringel K (2012) Activation of cell-mediated immunity in depression: association with inflammation, melancholia, clinical staging and the fatigue and somatic symptom cluster of depression. Prog Neuropsychopharmacol Biol Psych 36:169-175
    • (2012) Prog Neuropsychopharmacol Biol Psych , vol.36 , pp. 169-175
    • Maes, M.1    Mihaylova, I.2    Kubera, M.3    Ringel, K.4
  • 55
    • 84855297359 scopus 로고    scopus 로고
    • Fear conditioning, synaptic plasticity and the amygdala: Implications for posttraumatic stress disorder
    • Mahan AL, Ressler KJ (2012) Fear conditioning, synaptic plasticity and the amygdala: implications for posttraumatic stress disorder. Trends Neurosci 35:24-35
    • (2012) Trends Neurosci , vol.35 , pp. 24-35
    • Mahan, A.L.1    Ressler, K.J.2
  • 56
    • 0032584922 scopus 로고    scopus 로고
    • Effects of 7-nitroindazole, a neuronal nitric oxide synthase (nNOS) inhibitor, on locomotor activity and contextual fear conditioning in rats
    • Maren S (1998) Effects of 7-nitroindazole, a neuronal nitric oxide synthase (nNOS) inhibitor, on locomotor activity and contextual fear conditioning in rats. Brain Res 804:155-158
    • (1998) Brain Res , vol.804 , pp. 155-158
    • Maren, S.1
  • 58
    • 0032720683 scopus 로고    scopus 로고
    • Lessons from genetically engineered animal models. IV. Nitric oxide synthase gene knockout mice
    • Mashimo H, Goyal RK (1999) Lessons from genetically engineered animal models. IV. Nitric oxide synthase gene knockout mice. Am J Physiol 277:G745-750
    • (1999) Am J Physiol , vol.277 , pp. G745-750
    • Mashimo, H.1    Goyal, R.K.2
  • 60
    • 84876079221 scopus 로고    scopus 로고
    • Cytokine targets in the brain: Impact on neurotransmitters and neurocircuits
    • Miller AH, Haroon E, Raison CL, Felger JC (2013) Cytokine targets in the brain: impact on neurotransmitters and neurocircuits. Depress Anxiety 30:297-306
    • (2013) Depress Anxiety , vol.30 , pp. 297-306
    • Miller, A.H.1    Haroon, E.2    Raison, C.L.3    Felger, J.C.4
  • 61
    • 0031985513 scopus 로고    scopus 로고
    • Microglia as effector cells in brain damage and repair: Focus on prostanoids and nitric oxide
    • Minghetti L, Levi G (1998) Microglia as effector cells in brain damage and repair: focus on prostanoids and nitric oxide. Prog Neurobiol 54:99-125
    • (1998) Prog Neurobiol , vol.54 , pp. 99-125
    • Minghetti, L.1    Levi, G.2
  • 62
    • 0027231058 scopus 로고
    • Stress preferentially increases extraneuronal levels of excitatory amino acids in the prefrontal cortex: Comparison to hippocampus and basal ganglia
    • Moghaddam B (1993) Stress preferentially increases extraneuronal levels of excitatory amino acids in the prefrontal cortex: comparison to hippocampus and basal ganglia. J Neurochem 60:1650-1657
    • (1993) J Neurochem , vol.60 , pp. 1650-1657
    • Moghaddam, B.1
  • 63
    • 65649134782 scopus 로고    scopus 로고
    • Cytokines and schizophrenia: Microglia hypothesis of schizophrenia
    • Monji A, Kato T, Kanba S (2009) Cytokines and schizophrenia: microglia hypothesis of schizophrenia. Psychiatry Clin Neurosci 63:257-265
    • (2009) Psychiatry Clin Neurosci , vol.63 , pp. 257-265
    • Monji, A.1    Kato, T.2    Kanba, S.3
  • 65
    • 84891063237 scopus 로고    scopus 로고
    • Involvement of dorsal hippocampus glutamatergic and nitrergic neurotransmission in autonomic responses evoked by acute restraint stress in rats
    • Moraes-Neto TB, Scopinho AA, Biojone C, Correa FM, Resstel LB (2014) Involvement of dorsal hippocampus glutamatergic and nitrergic neurotransmission in autonomic responses evoked by acute restraint stress in rats. Neuroscience 258:364-373
    • (2014) Neuroscience , vol.258 , pp. 364-373
    • Moraes-Neto, T.B.1    Scopinho, A.A.2    Biojone, C.3    Correa, F.M.4    Resstel, L.B.5
  • 67
    • 84857133914 scopus 로고    scopus 로고
    • Cannabinoid type 1 receptors and transient receptor potential vanilloid type 1 channels in fear and anxiety-two sides of one coin?
    • Moreira FA, Aguiar DC, Terzian AL, Guimaraes FS, Wotjak CT (2012) Cannabinoid type 1 receptors and transient receptor potential vanilloid type 1 channels in fear and anxiety-two sides of one coin? Neuroscience 204:186-192
    • (2012) Neuroscience , vol.204 , pp. 186-192
    • Moreira, F.A.1    Aguiar, D.C.2    Terzian, A.L.3    Guimaraes, F.S.4    Wotjak, C.T.5
  • 70
    • 79960377311 scopus 로고    scopus 로고
    • Stress, glucocorticoids and glutamate release: Effects of antidepressant drugs
    • Musazzi L, Racagni G, Popoli M (2011) Stress, glucocorticoids and glutamate release: effects of antidepressant drugs. Neurochem Int 59:138-149
    • (2011) Neurochem Int , vol.59 , pp. 138-149
    • Musazzi, L.1    Racagni, G.2    Popoli, M.3
  • 71
    • 33847636300 scopus 로고    scopus 로고
    • The disruptive effects of the CB1 receptor antagonist rimonabant on extinction learning in mice are task-specific
    • Niyuhire F, Varvel SA, Thorpe AJ, Stokes RJ, Wiley JL, Lichtman AH (2007) The disruptive effects of the CB1 receptor antagonist rimonabant on extinction learning in mice are task-specific. Psychopharmacology (Berl) 191:223-231
    • (2007) Psychopharmacology (Berl , vol.191 , pp. 223-231
    • Niyuhire, F.1    Varvel, S.A.2    Thorpe, A.J.3    Stokes, R.J.4    Wiley, J.L.5    Lichtman, A.H.6
  • 74
    • 33544460655 scopus 로고    scopus 로고
    • Nitric oxide as inflammatory mediator in post-traumatic stress disorder (PTSD): Evidence from an animal model
    • Oosthuizen F, Wegener G, Harvey BH (2005) Nitric oxide as inflammatory mediator in post-traumatic stress disorder (PTSD): evidence from an animal model. Neuropsychiatr Disease Treatment 1:109-123
    • (2005) Neuropsychiatr Disease Treatment , vol.1 , pp. 109-123
    • Oosthuizen, F.1    Wegener, G.2    Harvey, B.H.3
  • 75
    • 34248530643 scopus 로고    scopus 로고
    • The cannabinoid receptor agonist WIN 55, 212-2 facilitates the extinction of contextual fear memory and spatial memory in rats
    • Pamplona FA, Prediger RD, Pandolfo P, Takahashi RN (2006) The cannabinoid receptor agonist WIN 55, 212-2 facilitates the extinction of contextual fear memory and spatial memory in rats. Psychopharmacology (Berl) 188:641-649
    • (2006) Psychopharmacology (Berl , vol.188 , pp. 641-649
    • Pamplona, F.A.1    Prediger, R.D.2    Pandolfo, P.3    Takahashi, R.N.4
  • 76
    • 33745261630 scopus 로고    scopus 로고
    • Pharmacological evaluation of cannabinoid receptor ligands in a mouse model of anxiety: Further evidence for an anxiolytic role for endogenous cannabinoid signaling
    • Patel S, Hillard CJ (2006) Pharmacological evaluation of cannabinoid receptor ligands in a mouse model of anxiety: further evidence for an anxiolytic role for endogenous cannabinoid signaling. J Pharmacol Exp Ther 318:304-311
    • (2006) J Pharmacol Exp Ther , vol.318 , pp. 304-311
    • Patel, S.1    Hillard, C.J.2
  • 77
    • 84883432098 scopus 로고    scopus 로고
    • Neuronal nitric-oxide synthase deficiency impairs the long-term memory of olfactory fear learning and increases odor generalization
    • Pavesi E, Heldt SA, Fletcher ML (2013) Neuronal nitric-oxide synthase deficiency impairs the long-term memory of olfactory fear learning and increases odor generalization. Learn Mem 20:482-490
    • (2013) Learn Mem , vol.20 , pp. 482-490
    • Pavesi, E.1    Heldt, S.A.2    Fletcher, M.L.3
  • 78
    • 84860194760 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase is involved in the modulation of depressive behaviors induced by unpredictable chronic mild stress
    • Peng YL, Liu YN, Liu L, Wang X, Jiang CL, Wang YX (2012) Inducible nitric oxide synthase is involved in the modulation of depressive behaviors induced by unpredictable chronic mild stress. J Neuroinflammation 9:75
    • (2012) J Neuroinflammation , vol.9 , pp. 75
    • Peng, Y.L.1    Liu, Y.N.2    Liu, L.3    Wang, X.4    Jiang, C.L.5    Wang, Y.X.6
  • 79
    • 0242268553 scopus 로고    scopus 로고
    • The molecular logic of endocannabinoid signalling
    • Piomelli D (2003) The molecular logic of endocannabinoid signalling. Nature reviews Neuroscience 4:873-884
    • (2003) Nature Reviews Neuroscience , vol.4 , pp. 873-884
    • Piomelli, D.1
  • 81
    • 50249146943 scopus 로고    scopus 로고
    • Endocannabinoid modulation of fear responses: Learning and state-dependent performance effects
    • Reich CG, Mohammadi MH, Alger BE (2008) Endocannabinoid modulation of fear responses: learning and state-dependent performance effects. J Psychopharmacol 22:769-777
    • (2008) J Psychopharmacol , vol.22 , pp. 769-777
    • Reich, C.G.1    Mohammadi, M.H.2    Alger, B.E.3
  • 83
    • 54149092167 scopus 로고    scopus 로고
    • The expression of contextual fear conditioning involves activation of an NMDA receptor-nitric oxide pathway in the medial prefrontal cortex
    • Resstel LB, Correa FM, Guimaraes FS (2008) The expression of contextual fear conditioning involves activation of an NMDA receptor-nitric oxide pathway in the medial prefrontal cortex. Cereb Cortex 18:2027-2035
    • (2008) Cereb Cortex , vol.18 , pp. 2027-2035
    • Resstel, L.B.1    Correa, F.M.2    Guimaraes, F.S.3
  • 85
    • 84867583020 scopus 로고    scopus 로고
    • Biphasic effects of cannabinoids in anxiety responses: CB1 and GABA(B) receptors in the balance of GABAergic and glutamatergic neurotransmission
    • Rey AA, Purrio M, Viveros MP, Lutz B (2012) Biphasic effects of cannabinoids in anxiety responses: CB1 and GABA(B) receptors in the balance of GABAergic and glutamatergic neurotransmission. Neuropsychopharmacology 37:2624-2634
    • (2012) Neuropsychopharmacology , vol.37 , pp. 2624-2634
    • Rey, A.A.1    Purrio, M.2    Viveros, M.P.3    Lutz, B.4
  • 87
    • 33646756221 scopus 로고    scopus 로고
    • Effects of cannabinoids on the anxiety-like response in mice
    • Rutkowska M, Jamontt J, Gliniak H (2006) Effects of cannabinoids on the anxiety-like response in mice. Pharmacol Rep 58:200-206
    • (2006) Pharmacol Rep , vol.58 , pp. 200-206
    • Rutkowska, M.1    Jamontt, J.2    Gliniak, H.3
  • 90
    • 84894055957 scopus 로고    scopus 로고
    • Schizophrenia: One coat of many colors
    • Smythies J (2013) Schizophrenia: one coat of many colors. Front Psychiatry 4:43
    • (2013) Front Psychiatry , vol.4 , pp. 43
    • Smythies, J.1
  • 92
    • 33646199097 scopus 로고    scopus 로고
    • Synaptic scaling mediated by glial TNF-Alpha
    • Stellwagen D, Malenka RC (2006) Synaptic scaling mediated by glial TNF-Alpha. Nature 440:1054-1059
    • (2006) Nature , vol.440 , pp. 1054-1059
    • Stellwagen, D.1    Malenka, R.C.2
  • 93
  • 94
    • 79957961935 scopus 로고    scopus 로고
    • Inhibition of the NMDA receptor/Nitric Oxide pathway in the dorsolateral periaqueductal gray causes anxiolyticlike effects in rats submitted to the Vogel conflict test
    • Tonetto LL, Terzian AL, Del Bel EA, Guimaraes FS, Resstel LB (2009) Inhibition of the NMDA receptor/Nitric Oxide pathway in the dorsolateral periaqueductal gray causes anxiolyticlike effects in rats submitted to the Vogel conflict test. Behav Brain Funct 5:40
    • (2009) Behav Brain Funct , vol.5 , pp. 40
    • Tonetto, L.L.1    Terzian, A.L.2    Del Bel, E.A.3    Guimaraes, F.S.4    Resstel, L.B.5
  • 95
    • 20044381340 scopus 로고    scopus 로고
    • Disruption of CB 1 receptor signaling impairs extinction of spatial memory in mice
    • Varvel SA, Anum EA, Lichtman AH (2005) Disruption of CB(1) receptor signaling impairs extinction of spatial memory in mice. Psychopharmacology (Berl) 179:863-872
    • (2005) Psychopharmacology Berl , vol.179 , pp. 863-872
    • Varvel, S.A.1    Anum, E.A.2    Lichtman, A.H.3
  • 96
    • 34247893850 scopus 로고    scopus 로고
    • Positron tomographic emission study of olfactory induced emotional recall in veterans with and without combatrelated posttraumatic stress disorder
    • Vermetten E, Schmahl C, Southwick SM, Bremner JD (2007) Positron tomographic emission study of olfactory induced emotional recall in veterans with and without combatrelated posttraumatic stress disorder. Psychopharmacol Bull 40:8-30
    • (2007) Psychopharmacol Bull , vol.40 , pp. 8-30
    • Vermetten, E.1    Schmahl, C.2    Southwick, S.M.3    Bremner, J.D.4
  • 97
  • 98
    • 84883687369 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase and NADPH oxidase interact to affect cognitive, affective, and social behaviors in mice
    • Walton JC, Selvakumar B, Weil ZM, Snyder SH, Nelson RJ (2013) Neuronal nitric oxide synthase and NADPH oxidase interact to affect cognitive, affective, and social behaviors in mice. Behav Brain Res 256:320-327
    • (2013) Behav Brain Res , vol.256 , pp. 320-327
    • Walton, J.C.1    Selvakumar, B.2    Weil, Z.M.3    Snyder, S.H.4    Nelson, R.J.5
  • 102
    • 0037177601 scopus 로고    scopus 로고
    • Endocannabinoid signaling in the brain
    • Wilson RI, Nicoll RA (2002) Endocannabinoid signaling in the brain. Science 296:678-682
    • (2002) Science , vol.296 , pp. 678-682
    • Wilson, R.I.1    Nicoll, R.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.