Involvement of NO-cGMP pathway in anti-anxiety effect of aminoguanidine in stressed mice

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 33, Issue 8, 2009, Pages 1502-1507

  Gilhotra, Neeraj ^a   Dhingra, Dinesh ^a  

^a GURU JAMBHESHWAR UNIVERSITY OF SCIENCE AND TECHNOLOGY   (India)

Author keywords

Aminoguanidine; Anxiety; Inducible nitric oxide synthase; Nitric oxide; Sildenafil

Indexed keywords

AMINOGUANIDINE; CYCLIC GMP; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITRITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY DISORDER; ARTICLE; CONTROLLED STUDY; FEMALE; IMMOBILIZATION STRESS; LIGHT DARK CYCLE; LOCOMOTION; MALE; MAZE TEST; MOUSE; NONHUMAN; OPEN FIELD TEST; SIGNAL TRANSDUCTION; SOCIAL INTERACTION; TRANQUILIZING ACTIVITY;

ADAPTATION, OCULAR; ANALYSIS OF VARIANCE; ANIMALS; ANTI-ASTHMATIC AGENTS; CYCLIC GMP; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; EXPLORATORY BEHAVIOR; FEMALE; GUANIDINES; INTERPERSONAL RELATIONS; MALE; MAZE LEARNING; MICE; NITRIC OXIDE; NITRITES; PIPERAZINES; PURINES; RESTRAINT, PHYSICAL; SIGNAL TRANSDUCTION; STRESS, PSYCHOLOGICAL; SULFONES;

EID: 71649090126     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2009.08.012     Document Type: Article

References (49)

1. André M., Latado H., and Felley-Bosco E. Inducible nitric oxide synthase-dependent stimulation of PKGI and phosphorylation of VASP in human embryonic kidney cells. Biochem Pharmacol 69 (2005) 595-602
2. Bhattacharya S.K., and Bhattachatyya D. Effect of restraint stress on rat brain serotonin. J Biosci 4 (1982) 269-274
3. Bredt D.S., Glatt C.E., Hwang P.M., Fotuhi M., Dawson T.M., and Snyder S.H. Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase. Neuron 7 (1991) 615-624
4. Crawley J., and Goodwin F.K. Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines. Pharmacol Biochem Behav 13 (1980) 167-170
5. Cullinan W.E., and Wolfe T.J. Chronic stress regulate level of mRNA transcripts encoding beta subunits of the GABA(A) receptor in the rat stress axis. Brain Res 887 (2000) 118-124
6. De Oliveira R.W., Forestiero D., Manfrim C.M., and Guimar~aes F.S. Anxiolytic effect induced by nitric oxide synthase inhibitors microinjected at medial amygdala of rats. Psychopharmacology 184 (2006) 166-172
7. Eroglu L., and Caglayan B. Anxiolytic and antidepressant properties of methylene blue in animal models. Pharmacol Res 36 (1997) 381-385
8. Esch T., Stefano G.B., Fricchione G.L., and Benson H. The role of stress in neurodegenerative diseases and mental disorders. Neuro Endocrinol Lett 23 (2002) 199-208
9. Faria M.S., Muscara M.N., Moreno J.H., Teixeira S.A., Dias H.B., De Oliveira B., et al. Acute inhibition of nitric oxide synthesis induces anxiolysis in the plus maze test. Eur J Pharmacol 323 (1997) 37-43
10. File S.E. The use of social interaction as a method for detecting anxiolytic activity of chlordiazepoxide-like drugs. J Neurosci Methods 2 (1996) 219-238
11. Friebe A., and Koesling D. Regulation of nitric oxide-sensitive guanylyl cyclase. Circ Res 93 (2003) 96-105
12. Garthwaite J. Glutamate, nitric oxide and cell-cell signaling in the nervous system. Trends Neurosci 14 (1991) 60-67
13. Gow A.J., Farkouh C.R., Munson D.A., Posencheg M.A., and Ischiropoulos H. Biological significance of nitric oxide-mediated protein modifications. Am J Physiol, Lung Cell Mol Physiol 287 (2004) L262-L268
14. Green L.C., Wagner D.A., Glogowski J., Skipper P.L., Wishnock J.S., and Tannenbaum S.R. Analysis of nitrate, nitrite, and [N-15N]-labelled nitrate in biological fluids. Anal Biochem 126 (1982) 131-138
15. Griffiths M.J., Messent M., Curzen N.P., and Evans T.W. Aminoguanidine selectively decreases cyclic GMP levels produced by inducible nitric oxide synthase. Am J Respir Crit Care Med 152 (1995) 1599-1604
16. Halaris A., and Plietz J. Agmatin: metabolic pathway and spectrum of activity in brain. CNS Drugs 21 (2007) 885-900
17. Ishizuka Y., Ishida Y., Jin Q.H., Mitsuyama Y., and Kannan H. GABA(A) and GABA(B) receptors modulating basal and footshock-induced nitric oxide release in rat prefrontal cortex. Brain Res 872 (2000) 266-270
18. Korte S.M., and De Boer S.F. A robust animal model of state anxiety: fear-potentiated behaviour in the elevated plus-maze. Eur J Pharmacol 463 (2003) 163-175
19. Kulkarni S.K. Handbook of experimental pharmacology. 3rd ed. (1999), Vallabh Prakashan, Delhi
20. Kurt M., Bilge S.S., Aksoz E., Kukula O., Celik S., and Kesim Y. Effect of sildenafill on anxiety in the plus-maze test in mice. Pol J Pharmacol 56 (2004) 353-357
21. Madrigal J.L., Moro M.A., Lizasaoin I., Lorenzo P., Castrillo A., Bosca L., et al. Inducible nitric oxide synthase expression in brain cortex after acute restraint stress is regulated by nuclear factor kappaB-mediated mechanisms. J Neurochem 76 (2001) 532-538
22. Madrigal J.L.M., Olivia H.O., Moro M.A., Lizasoain I., Lorenzo P., Castrillo A., et al. The increase in TNF-α Levels is implicated in NF-κB activation and inducible nitric oxide synthase expression in brain cortex after immobilization stress. Neuropsychopharmacology 26 (2002) 155-163
23. McHugh S.B., Deacon R.M., Rawlins J.N., and Bannerman D.M. Amygdala and ventral hippocampus contribute differentially to mechanisms of fear and anxiety. Behav Neurosci 118 (2004) 63-78
24. McNaughton N., and Corr P.J. A two-dimensional neuropsychology of defense: fear/anxiety and defensive distance. Neurosci Biobehav Rev 28 (2004) 285-305
25. Milman H.A., and Arnold S.B. Neurologic, psychological and aggressive disturbances with sildenafil. Ann Pharmacother 36 (2002) 1129-1134
26. Misko T.P., Moore W.M., Kasten T.P., Nickols G.A., Corbett J.A., Tilton R.G., et al. Selective inhibition of the inducible nitric oxide synthase by aminoguanidine. Eur J Pharmacol 233 (1993) 119-125
27. Moreira F.A., Molchanov M.L., and Guimaraes F.S. Ionotropic glutamate-receptor antagonists inhibit the aversive effects of nitric oxide donor injected into dorsolateral periaqueductal gray of rats. Psychopharmacology 171 (2004) 199-203
28. Munhoz C.D., García-Bueno B., Madrigal J.L.M., Lepsch L.B., Scavone C., and Leza J.C. Stress-induced neuroinflammation: mechanisms and new pharmacological targets. Braz J Med Biol Res 41 (2008) 1037-1046
29. Nagao K., Takenaka S., Yamaji R., Inui H., and Nakano Y. Nitric oxide synthase induction, cGMP elevation, and biopterin synthesis in vascular smooth muscle cells stimulated with interleukin-1beta in hypoxia. J Biochem 133 4 (2003) 501-505
30. Nakashima M.N., Ajiki K., Nakashima K., and Takahashi M. Possible role of nitric oxide in anxiety following transient cerebral ischemia in mice. J Pharm Sci 91 (2003) 47-52
31. Olivenza R., Moro M.A., Lizasoain L., Lorenzo P., Fernández A.P., Rodrigo J., et al. Chronic stress induces the expression of inducible nitric oxide synthase in rat brain cortex. J Neurochem 74 (2000) 785-791
32. Robello M., Amico C., Bucossi G., Cupello A., Rapallino M.V., and Thellung S. Nitric oxide and GABAA receptor function in the rat cerebral cortex and cerebellar granule cells. Neuroscience 74 (1996) 99-105
33. Schwartz T.L., Nihalani N., Simionescu M., and Hopkins G. History repeats itself: pharmacodynamic trends in the treatment of anxiety disorders. Curr Pharm Des 11 (2005) 255-263
34. Sevgi S., Ozek M., and Eroglu L. L-NAME prevents anxiety-like and depression-like behavior in rats exposed to restraint stress. Methods Find Exp Clin Pharmacol 28 (2006) 95-99
35. Snyder S.H., and Bredt D.S. Nitric oxide as a neural messenger. Trends Pharmacol Sci 12 (1991) 125-128
36. Southam E., and Garthwaite J. The nitric oxide-cyclic GMP signaling pathway in rat brain. Neuropharmacology 32 (1993) 1267-1277
37. Southan J.G., and Szabo C. Selective pharmacological inhibition of distinct nitric oxide synthase isoforms. Biochem Pharmacol 51 (1996) 383-394
38. Spolidório P.C., Echeverry M.B., Iyomasa M., Guimarães F.S., and Del Bel E.A. Anxiolytic effects induced by inhibition of the nitric oxide-cGMP pathway in the rat dorsal hippocampus. Psychopharmacology 195 (2007) 183-192
39. Tanaka M., Ikeda T., Hayashi S., Iijima N., Amaya F., Hisa Y., et al. Nitrergic neurons in the medial amygdala project to the hypothalamic paraventricular nucleus of the rat. Brain Res 777 (1997) 13-21
40. Thomas M., and Feron O. Nitric oxide synthases: which, where, how, and why?. J Clin Invest 100 (1997) 2146-2152
41. Toriizuka K., Kamiki H., Ohmura N., Fuji M., Hori Y., Fukumura M., et al. Anxiolytic effect of Gardinae Fructus extract containing active ingredient from Kamishoyosan, a Japanese traditional Kempo medicine. Life Sci 77 (2005) 3010-3020
42. Tsuchiya T., Kishimoto J., Koyama J., and Ozawa T. Modulatory effect of L-NAME, a specific nitric oxide synthase (NOS) inhibitor, on stress-induced changes in plasma adrenocorticotropic hormone and corticosterone levels in rats: physiological significance of stress-induced NOS activation in hypothalamic-pituitary-adrenal axis. Brain Res 776 (1997) 68-74
43. Vincent S.R. Nitric oxide: a radical neurotransmitter in the central nervous system. Prog Neurobiol 42 (1994) 129
44. Volke V., and Vasar E. Phosphodiesterase type 5 inhibitor sildenafil has anxiogenic-like properties in mouse light-dark compartment test. 15th ECNP Congress, Barcelona, Spain (1997) 6.023
45. Volke V., Soosar A., Koks S., Bourin M., Mannisto P.T., and Vasar E. 7-Nitroindazole, a nitric oxide synthase inhibitor, has anxiolytic-like properties in exploratory models of anxiety. Psychopharmacol 131 (1997) 399-405
46. Volke V., Wegener G., Bourin M., and Vasar E. Antidepressant- and anxiolytic-like effects of selective neuronal NOS inhibitor 1-(2-trifluoromethylphenyl)-imidazole in mice. Behav Brain Res 140 (2003) 141-147
47. Wexler E.M., Stanton P.K., and Nawy S. Nitric oxide depresses GABAA receptor function via coactivation of cGMP-dependent kinase and phosphodiesterase. J Neurosci 18 (1998) 2342-2349
48. Yildiz F., Ulak G., Erden B.F., and Gacar N. Anxiolytic-like effects of 7-nitroindazole in the rat plus-maze test. Pharmacol Biochem Behav 65 (2000) 199-202
49. Zarri I., Bucossi G., Cupello A., Rapallino M.V., and Robello M. Modulation by nitric oxide of rat brain GABAA receptors. Neurosci Lett 180 (1994) 239-242