Efficient peroral delivery of insulin via vitamin B12 modified trimethyl chitosan nanoparticles

Journal of Pharmacy and Pharmaceutical Sciences

Volumn 18, Issue 2, 2015, Pages 155-170

  Ke, Zhiyang ^a   Guo, Han ^a   Zhu, Xi ^a   Jin, Yun ^a   Huang, Yuan ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHITOSAN NANOPARTICLE; CYANOCOBALAMIN; INSULIN; TRIMETHYL CHITOSAN NANOPARTICLE; UNCLASSIFIED DRUG; CHITOSAN; DRUG CARRIER; N-TRIMETHYL CHITOSAN CHLORIDE; NANOPARTICLE;

ARTICLE; CACO 2 CELL LINE; CAVEOLAE MEDIATED ENDOCYTOSIS PATHWAY; CELL LINE; CLATHRIN MEDIATED ENDOCYTOSIS PATHWAY; COCULTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG LOADING EFFICIENCY; DRUG TRANSPORT; DRUG UPTAKE; ENCAPSULATION EFFICIENCY; ENDOCYTOSIS; HT 29 CELL LINE; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; LIGAND RECEPTOR INTERACTION; MTX CELL LINE; NONHUMAN; ORAL DRUG DELIVERY; PARTICLE SIZE; PHYSICAL CHEMISTRY; POLYDISPERSITY INDEX; PROTEIN INTERACTION; RAT; ZETA POTENTIAL; ANIMAL; CELL CULTURE; CHEMISTRY; HUMAN; INTESTINE; MALE; METABOLISM; ORAL DRUG ADMINISTRATION; SPRAGUE DAWLEY RAT; SYNTHESIS;

ADMINISTRATION, ORAL; ANIMALS; CACO-2 CELLS; CELLS, CULTURED; CHITOSAN; DRUG CARRIERS; HT29 CELLS; HUMANS; INSULIN; INTESTINES; MALE; NANOPARTICLES; RATS; RATS, SPRAGUE-DAWLEY; VITAMIN B 12;

EID: 84931267784     PISSN: None     EISSN: 14821826     Source Type: Journal    
DOI: 10.18433/j3j88q     Document Type: Article

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