Preparation and evaluation of anti-neuroexcitation peptide (ANEP) loaded N-trimethyl chitosan chloride nanoparticles for brain-targeting

International Journal of Pharmaceutics

Volumn 386, Issue 1-2, 2010, Pages 249-255

  Wang, Siling ^a   Jiang, Tongying ^a   Ma, Mingxin ^a   Hu, Yanchen ^a   Zhang, Jinghai ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Anti neuroexcitation peptide; Biodistribution; Brain targeting; N Trimethyl chitosan chloride; Nanoparticles

Indexed keywords

ANTINEUROEXCITATION PEPTIDE; CHITOSAN DERIVATIVE; FLUORESCEIN ISOTHIOCYANATE; N TRIMETHYLCHITOSAN CHLORIDE; RECOMBINANT PROTEIN; SCORPION VENOM; TRIPOLYPHOSPHATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BUTHUS MARTENSII; CONTROLLED STUDY; CROSS LINKING; DRUG BRAIN LEVEL; DRUG STABILITY; DRUG TARGETING; DRUG TISSUE LEVEL; ENCAPSULATION; EXCITOTOXICITY; MALE; MAXIMUM PLASMA CONCENTRATION; MOUSE; NONHUMAN; PARTICLE SIZE; PH; PRIORITY JOURNAL; SCORPION; TISSUE DISTRIBUTION; TRANSCYTOSIS; ZETA POTENTIAL;

ANIMALS; BIOLOGICAL TRANSPORT; BRAIN; CHEMISTRY, PHARMACEUTICAL; CHITOSAN; CROSS-LINKING REAGENTS; DRUG CARRIERS; DRUG COMPOUNDING; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; MALE; MICE; NANOPARTICLES; NANOTECHNOLOGY; PERMEABILITY; POLYPHOSPHATES; PROTEIN STABILITY; SCORPION VENOMS; SPECTROMETRY, FLUORESCENCE; TECHNOLOGY, PHARMACEUTICAL; TISSUE DISTRIBUTION;

EID: 74149094269     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.11.002     Document Type: Article

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