Single molecule-level detection and long read-based phasing of epigenetic variations in bacterial methylomes

Nature Communications

Volumn 6, Issue , 2015, Pages

  Beaulaurier, John ^a   Zhang, Xue Song ^b   Zhu, Shijia ^a   Sebra, Robert ^a   Rosenbluh, Chaggai ^a   Deikus, Gintaras ^a   Shen, Nan ^a   Munera, Diana ^c   Waldor, Matthew K ^c   Chess, Andrew ^a   Blaser, Martin J ^b   Schadt, Eric E ^a   Fang, Gang ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 N METHYLADENINE; BACTERIAL DNA; N 4 METHYLCYTOSINE; UNCLASSIFIED DRUG; DNA METHYLTRANSFERASE;

ANTIBIOTIC RESISTANCE; BACTERIUM; CELLS AND CELL COMPONENTS; CLONAL ORGANISM; DETECTION METHOD; DNA; GENE EXPRESSION; GENETIC VARIATION; HETEROGENEITY; METHYLATION; MICROBIAL COMMUNITY; MOLECULAR ANALYSIS; PHENOTYPIC PLASTICITY; VIRULENCE;

ADULT; ANALYTIC METHOD; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL CELL; BACTERIAL GENOME; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CELL CLONING; DNA METHYLATION; DNA SEQUENCE; EPIGENETICS; ESCHERICHIA COLI; FEMALE; FRAMESHIFT MUTATION; GENE AMPLIFICATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC HETEROGENEITY; GENETIC VARIABILITY; HELICOBACTER PYLORI; HUMAN; INDEL MUTATION; MIDDLE AGED; NONHUMAN; PHENOTYPIC PLASTICITY; PROTEIN MOTIF; SENSITIVITY AND SPECIFICITY; SINGLE MOLECULE MODIFICATION ANALYSIS OF LONG READ; CAMPYLOBACTER JEJUNI; CAULOBACTER VIBRIOIDES; CHROMOHALOBACTER; GENETIC EPIGENESIS; GENETICS; GEOBACTER; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE;

BACTERIA (MICROORGANISMS);

BASE SEQUENCE; CAMPYLOBACTER JEJUNI; CAULOBACTER CRESCENTUS; CHROMOHALOBACTER; DNA METHYLATION; DNA MODIFICATION METHYLASES; DNA, BACTERIAL; EPIGENESIS, GENETIC; ESCHERICHIA COLI; GENOME, BACTERIAL; GEOBACTER; HELICOBACTER PYLORI; MOLECULAR SEQUENCE DATA; SEQUENCE ANALYSIS, DNA;

EID: 84931267351     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8438     Document Type: Article

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