Baicalein increases the expression and reciprocal interplay of RUNX3 and FOXO3a through crosstalk of AMPKα and MEK/ERK1/2 signaling pathways in human non-small cell lung cancer cells

Journal of Experimental and Clinical Cancer Research

Volumn 34, Issue 1, 2015, Pages

  Zheng, Fang ^a   Wu, Jingjing ^a   Zhao, Shunyu ^a   Luo, Qingmei ^a   Tang, Qing ^a   Yang, Lijun ^a   Li, Liuning ^a   Wu, Wanying ^a   Hann, Swei Sunny ^a,b  

^a GUANGDONG PROVINCIAL HOSPITAL OF CHINESE MEDICINE   (China)

^b Higher Education Mega Center   (China)

Author keywords

AMPKa; Baicalein; FOXO3a; MEK ERK1 2; NSCLC; RUNX3

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; BAICALEIN; CASPASE 3; CASPASE 7; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN AMPKALPHA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR FKHRL1; TRANSCRIPTION FACTOR RUNX3; UNCLASSIFIED DRUG; FLAVANONE DERIVATIVE; FORKHEAD TRANSCRIPTION FACTOR; FOXO3 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CELL VIABILITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MTT ASSAY; NON SMALL CELL LUNG CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; LUNG TUMOR; METABOLISM; TUMOR CELL LINE;

AMP-ACTIVATED PROTEIN KINASES; APOPTOSIS; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CELL PROLIFERATION; CORE BINDING FACTOR ALPHA 3 SUBUNIT; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVANONES; FORKHEAD BOX PROTEIN O3; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; MAP KINASE SIGNALING SYSTEM;

EID: 84931073876     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/s13046-015-0160-7     Document Type: Article

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