Extracellular signal-regulated kinase signaling-mediated induction and interaction of FOXO3a and p53 contribute to the inhibition of nasopharyngeal carcinoma cell growth by curcumin

International Journal of Oncology

Volumn 45, Issue 1, 2014, Pages 95-103

  Wu, Jingjing ^a   Tang, Qin ^a   Zhao, Shunyu ^a   Zheng, Fang ^a   Wu, Yan ^a   Tang, Ge ^a   Hahn, Swei Sunny ^a  

^a GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Curcumin; ERK1 2; FOXO3a; Nasopharyngeal carcinoma cells; P53

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; CURCUMIN; MITOGEN ACTIVATED PROTEIN KINASE; PROPIDIUM IODIDE; PROTEIN DERIVATIVE; PROTEIN P53; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR FKHRL1; 2-(2-AMINO-3-METHOXYPHENYL)-4H-1-BENZOPYRAN-4-ONE; ANTINEOPLASTIC AGENT; FLAVONOID; FORKHEAD TRANSCRIPTION FACTOR; FOXO3 PROTEIN, HUMAN; TP53 PROTEIN, HUMAN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL GROWTH; CELL PROLIFERATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; NASOPHARYNX CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; METABOLISM; NASOPHARYNX TUMOR; PATHOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CURCUMIN; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONOIDS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MAP KINASE SIGNALING SYSTEM; NASOPHARYNGEAL NEOPLASMS; PHOSPHORYLATION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84902589426     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2014.2420     Document Type: Article

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