-
1
-
-
0037059330
-
Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action
-
Aguirre V., Werner E.D., Giraud J., Lee Y.H., Shoelson S.E., White M.F. Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action. J. Biol. Chem. 2002, 277:1531-1537.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 1531-1537
-
-
Aguirre, V.1
Werner, E.D.2
Giraud, J.3
Lee, Y.H.4
Shoelson, S.E.5
White, M.F.6
-
2
-
-
0038464586
-
Main flavonoids in the root of I cultivated in Europe and their comparative antiradical properties
-
Bochorakova H., Paulova H., Slanina J., Musil P., Taborska E. Main flavonoids in the root of I cultivated in Europe and their comparative antiradical properties. Phytother. Res. 2003, 17:640-644.
-
(2003)
Phytother. Res.
, vol.17
, pp. 640-644
-
-
Bochorakova, H.1
Paulova, H.2
Slanina, J.3
Musil, P.4
Taborska, E.5
-
3
-
-
42649104331
-
The establishment of a novel non-alcoholic steatohepatitis model accompanied with obesity and insulin resistance in mice
-
Cong W.N., Tao R.Y., Tian J.Y., Liu G.T., Ye F. The establishment of a novel non-alcoholic steatohepatitis model accompanied with obesity and insulin resistance in mice. Life Sci. 2008, 82:983-990.
-
(2008)
Life Sci.
, vol.82
, pp. 983-990
-
-
Cong, W.N.1
Tao, R.Y.2
Tian, J.Y.3
Liu, G.T.4
Ye, F.5
-
4
-
-
77956059859
-
Baicalein is neuroprotective in rat MCAO model: role of 12/15-lipoxygenase, mitogen-activated protein kinase and cytosolic phospholipase A2
-
Cui L., Zhang X., Yang R., Liu L., Wang L., Li M., Du W. Baicalein is neuroprotective in rat MCAO model: role of 12/15-lipoxygenase, mitogen-activated protein kinase and cytosolic phospholipase A2. Pharmacol. Biochem. Behav. 2010, 96:469-475.
-
(2010)
Pharmacol. Biochem. Behav.
, vol.96
, pp. 469-475
-
-
Cui, L.1
Zhang, X.2
Yang, R.3
Liu, L.4
Wang, L.5
Li, M.6
Du, W.7
-
5
-
-
15444366991
-
Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation
-
Dandona P., Aljada A., Chaudhuri A., Mohanty P., Garg R. Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation. Circulation 2005, 111:1448-1454.
-
(2005)
Circulation
, vol.111
, pp. 1448-1454
-
-
Dandona, P.1
Aljada, A.2
Chaudhuri, A.3
Mohanty, P.4
Garg, R.5
-
6
-
-
37549022688
-
Inflammation and insulin resistance
-
de Luca C., Olefsky J.M. Inflammation and insulin resistance. FEBS Lett. 2008, 582:97-105.
-
(2008)
FEBS Lett.
, vol.582
, pp. 97-105
-
-
de Luca, C.1
Olefsky, J.M.2
-
7
-
-
80053979666
-
Novel synthetic baicalein derivatives caused apoptosis and activated AMP-activated protein kinase in human tumor cells
-
Ding D., Zhang B., Meng T., Ma Y., Wang X., Peng H., Shen J. Novel synthetic baicalein derivatives caused apoptosis and activated AMP-activated protein kinase in human tumor cells. Org. Biomol. Chem. 2011, 9:7287-7291.
-
(2011)
Org. Biomol. Chem.
, vol.9
, pp. 7287-7291
-
-
Ding, D.1
Zhang, B.2
Meng, T.3
Ma, Y.4
Wang, X.5
Peng, H.6
Shen, J.7
-
8
-
-
33644547706
-
Nonalcoholic fatty liver disease: from steatosis to cirrhosis
-
Farrell G.C., Larter C.Z. Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology 2006, 43:S99-S112.
-
(2006)
Hepatology
, vol.43
-
-
Farrell, G.C.1
Larter, C.Z.2
-
9
-
-
27444443876
-
Diagnosis and management of the metabolic syndrome: an american heart association/national heart, lung, and blood institute scientific statement
-
Grundy S.M., Cleeman J.I., Daniels S.R., Donato K.A., Eckel R.H., Franklin B.A., Gordon D.J., Krauss R.M., Savage P.J., Smith S.C., Spertus J.A., Costa F. Diagnosis and management of the metabolic syndrome: an american heart association/national heart, lung, and blood institute scientific statement. Circulation 2005, 112:2735-2752.
-
(2005)
Circulation
, vol.112
, pp. 2735-2752
-
-
Grundy, S.M.1
Cleeman, J.I.2
Daniels, S.R.3
Donato, K.A.4
Eckel, R.H.5
Franklin, B.A.6
Gordon, D.J.7
Krauss, R.M.8
Savage, P.J.9
Smith, S.C.10
Spertus, J.A.11
Costa, F.12
-
10
-
-
67049155945
-
Dissecting the role of insulin resistance in the metabolic syndrome
-
Haas J.T., Biddinger S.B. Dissecting the role of insulin resistance in the metabolic syndrome. Curr. Opin. Lipidol. 2009, 20:206-210.
-
(2009)
Curr. Opin. Lipidol.
, vol.20
, pp. 206-210
-
-
Haas, J.T.1
Biddinger, S.B.2
-
12
-
-
57749094239
-
AMP-activated protein kinase activation increases phosphorylation of glycogen synthase kinase 3beta and thereby reduces cAMP-responsive element transcriptional activity and phosphoenolpyruvate carboxykinase C gene expression in the liver
-
Horike N., Sakoda H., Kushiyama A., Ono H., Fujishiro M., Kamata H., Nishiyama K., Uchijima Y., Kurihara Y., Kurihara H., Asano T. AMP-activated protein kinase activation increases phosphorylation of glycogen synthase kinase 3beta and thereby reduces cAMP-responsive element transcriptional activity and phosphoenolpyruvate carboxykinase C gene expression in the liver. J. Biol. Chem. 2008, 283:33902-33910.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 33902-33910
-
-
Horike, N.1
Sakoda, H.2
Kushiyama, A.3
Ono, H.4
Fujishiro, M.5
Kamata, H.6
Nishiyama, K.7
Uchijima, Y.8
Kurihara, Y.9
Kurihara, H.10
Asano, T.11
-
13
-
-
13844314826
-
Herbal or natural medicines as modulators of peroxisome proliferator-activated receptors and related nuclear receptors for therapy of metabolic syndrome
-
Huang T.H., Kota B.P., Razmovski V., Roufogalis B.D. Herbal or natural medicines as modulators of peroxisome proliferator-activated receptors and related nuclear receptors for therapy of metabolic syndrome. Basic Clin. Pharmacol. Toxicol. 2005, 96:3-14.
-
(2005)
Basic Clin. Pharmacol. Toxicol.
, vol.96
, pp. 3-14
-
-
Huang, T.H.1
Kota, B.P.2
Razmovski, V.3
Roufogalis, B.D.4
-
14
-
-
71749100220
-
AMP-activated protein kinase: a potential target for the diseases prevention by natural occurring polyphenols
-
Hwang J.T., Kwon D.Y., Yoon S.H. AMP-activated protein kinase: a potential target for the diseases prevention by natural occurring polyphenols. N. Biotechnol. 2009, 26:17-22.
-
(2009)
N. Biotechnol.
, vol.26
, pp. 17-22
-
-
Hwang, J.T.1
Kwon, D.Y.2
Yoon, S.H.3
-
15
-
-
0034025809
-
Antitumor effects of Scutellariae radix and its components baicalein, baicalin, and wogonin on bladder cancer cell lines
-
Ikemoto S., Sugimura K., Yoshida N., Yasumoto R., Wada S., Yamamoto K., Kishimoto T. Antitumor effects of Scutellariae radix and its components baicalein, baicalin, and wogonin on bladder cancer cell lines. Urology 2000, 55:951-955.
-
(2000)
Urology
, vol.55
, pp. 951-955
-
-
Ikemoto, S.1
Sugimura, K.2
Yoshida, N.3
Yasumoto, R.4
Wada, S.5
Yamamoto, K.6
Kishimoto, T.7
-
16
-
-
0029039362
-
Histological grading and staging of chronic hepatitis
-
Ishak K., Baptista A., Bianchi L., Callea F., De Groote J., Gudat F., Denk H., Desmet V., Korb G., MacSween R.N., et al. Histological grading and staging of chronic hepatitis. J. Hepatol. 1995, 22:696-699.
-
(1995)
J. Hepatol.
, vol.22
, pp. 696-699
-
-
Ishak, K.1
Baptista, A.2
Bianchi, L.3
Callea, F.4
De Groote, J.5
Gudat, F.6
Denk, H.7
Desmet, V.8
Korb, G.9
MacSween, R.N.10
-
17
-
-
0035861644
-
5'-AMP-activated protein kinase phosphorylates IRS-1 on Ser-789 in mouse C2C12 myotubes in response to 5-aminoimidazole-4-carboxamide riboside
-
Jakobsen S.N., Hardie D.G., Morrice N., Tornqvist H.E. 5'-AMP-activated protein kinase phosphorylates IRS-1 on Ser-789 in mouse C2C12 myotubes in response to 5-aminoimidazole-4-carboxamide riboside. J. Biol. Chem. 2001, 276:46912-46916.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 46912-46916
-
-
Jakobsen, S.N.1
Hardie, D.G.2
Morrice, N.3
Tornqvist, H.E.4
-
18
-
-
0034882904
-
Cytoprotective effect of Scutellaria baicalensis in CA1 hippocampal neurons of rats after global cerebral ischemia
-
Kim Y.O., Leem K., Park J., Lee P., Ahn D.K., Lee B.C., Park H.K., Suk K., Kim S.Y., Kim H. Cytoprotective effect of Scutellaria baicalensis in CA1 hippocampal neurons of rats after global cerebral ischemia. J. Ethnopharmacol. 2001, 77:183-188.
-
(2001)
J. Ethnopharmacol.
, vol.77
, pp. 183-188
-
-
Kim, Y.O.1
Leem, K.2
Park, J.3
Lee, P.4
Ahn, D.K.5
Lee, B.C.6
Park, H.K.7
Suk, K.8
Kim, S.Y.9
Kim, H.10
-
19
-
-
33847637510
-
Improved glucose tolerance in mice receiving intraperitoneal transplantation of normal fat tissue
-
Konrad D., Rudich A., Schoenle E.J. Improved glucose tolerance in mice receiving intraperitoneal transplantation of normal fat tissue. Diabetologia 2007, 50:833-839.
-
(2007)
Diabetologia
, vol.50
, pp. 833-839
-
-
Konrad, D.1
Rudich, A.2
Schoenle, E.J.3
-
20
-
-
0033951870
-
Regulation of phenobarbital induction of the cytochrome P450 2b9/10 genes in primary mouse hepatocyte culture - involvement of calcium- and cAMP-dependent pathways
-
Marc N., Galisteo M., Lagadic-Gossmann D., Fautrel A., Joannard F., Guillouzo A., Corcos L. Regulation of phenobarbital induction of the cytochrome P450 2b9/10 genes in primary mouse hepatocyte culture - involvement of calcium- and cAMP-dependent pathways. Eur. J. Biochem. 2000, 267:963-970.
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 963-970
-
-
Marc, N.1
Galisteo, M.2
Lagadic-Gossmann, D.3
Fautrel, A.4
Joannard, F.5
Guillouzo, A.6
Corcos, L.7
-
21
-
-
0021813187
-
Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
-
Matthews D.R., Hosker J.P., Rudenski A.S., Naylor B.A., Treacher D.F., Turner R.C. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985, 28:412-419.
-
(1985)
Diabetologia
, vol.28
, pp. 412-419
-
-
Matthews, D.R.1
Hosker, J.P.2
Rudenski, A.S.3
Naylor, B.A.4
Treacher, D.F.5
Turner, R.C.6
-
22
-
-
70549093110
-
Role of NF-kappa B in the pathogenesis of diabetes and its associated complications
-
Patel S., Santani D. Role of NF-kappa B in the pathogenesis of diabetes and its associated complications. Pharmacol. Rep. 2009, 61:595-603.
-
(2009)
Pharmacol. Rep.
, vol.61
, pp. 595-603
-
-
Patel, S.1
Santani, D.2
-
23
-
-
77952743304
-
Flavonoids and age-related disease: risk, benefits and critical windows
-
Prasain J.K., Carlson S.H., Wyss J.M. Flavonoids and age-related disease: risk, benefits and critical windows. Maturitas 2010, 66:163-171.
-
(2010)
Maturitas
, vol.66
, pp. 163-171
-
-
Prasain, J.K.1
Carlson, S.H.2
Wyss, J.M.3
-
24
-
-
3843061592
-
AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome
-
Ruderman N., Prentki M. AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome. Nat. Rev. Drug. Discov. 2004, 3:340-351.
-
(2004)
Nat. Rev. Drug. Discov.
, vol.3
, pp. 340-351
-
-
Ruderman, N.1
Prentki, M.2
-
25
-
-
12244301218
-
Mechanisms in mediating the anti-inflammatory effects of baicalin and baicalein in human leukocytes
-
Shen Y.C., Chiou W.F., Chou Y.C., Chen C.F. Mechanisms in mediating the anti-inflammatory effects of baicalin and baicalein in human leukocytes. Eur. J. Pharmacol. 2003, 465:171-181.
-
(2003)
Eur. J. Pharmacol.
, vol.465
, pp. 171-181
-
-
Shen, Y.C.1
Chiou, W.F.2
Chou, Y.C.3
Chen, C.F.4
-
26
-
-
67650914230
-
AMPK in health and disease
-
Steinberg G.R., Kemp B.E. AMPK in health and disease. Physiol. Rev. 2009, 89:1025-1078.
-
(2009)
Physiol. Rev.
, vol.89
, pp. 1025-1078
-
-
Steinberg, G.R.1
Kemp, B.E.2
-
28
-
-
0036182137
-
Lipotoxic diseases
-
Unger R.H. Lipotoxic diseases. Annu. Rev. Med. 2002, 53:319-336.
-
(2002)
Annu. Rev. Med.
, vol.53
, pp. 319-336
-
-
Unger, R.H.1
-
29
-
-
33644633736
-
Biomarkers and potential mechanisms of obesity-induced oxidant stress in humans
-
Vincent H.K., Taylor A.G. Biomarkers and potential mechanisms of obesity-induced oxidant stress in humans. Int. J. Obes. (Lond). 2006, 30:400-418.
-
(2006)
Int. J. Obes. (Lond).
, vol.30
, pp. 400-418
-
-
Vincent, H.K.1
Taylor, A.G.2
-
30
-
-
0037326307
-
Physiological role of AMP-activated protein kinase (AMPK): insights from knockout mouse models
-
Viollet B., Andreelli F., Jorgensen S.B., Perrin C., Flamez D., Mu J., Wojtaszewski J.F., Schuit F.C., Birnbaum M., Richter E., Burcelin R., Vaulont S. Physiological role of AMP-activated protein kinase (AMPK): insights from knockout mouse models. Biochem. Soc. Trans. 2003, 31:216-219.
-
(2003)
Biochem. Soc. Trans.
, vol.31
, pp. 216-219
-
-
Viollet, B.1
Andreelli, F.2
Jorgensen, S.B.3
Perrin, C.4
Flamez, D.5
Mu, J.6
Wojtaszewski, J.F.7
Schuit, F.C.8
Birnbaum, M.9
Richter, E.10
Burcelin, R.11
Vaulont, S.12
-
31
-
-
38349006242
-
Berberine improves glucose metabolism through induction of glycolysis
-
Yin J., Gao Z., Liu D., Liu Z., Ye J. Berberine improves glucose metabolism through induction of glycolysis. Am. J. Physiol. Endocrinol. Metab. 2008, 294:E148-E156.
-
(2008)
Am. J. Physiol. Endocrinol. Metab.
, vol.294
-
-
Yin, J.1
Gao, Z.2
Liu, D.3
Liu, Z.4
Ye, J.5
-
32
-
-
0031726145
-
Resistance to insulin-mediated glucose disposal as a predictor of cardiovascular disease
-
Yip J., Facchini F.S., Reaven G.M. Resistance to insulin-mediated glucose disposal as a predictor of cardiovascular disease. J. Clin. Endocrinol. Metab. 1998, 83:2773-2776.
-
(1998)
J. Clin. Endocrinol. Metab.
, vol.83
, pp. 2773-2776
-
-
Yip, J.1
Facchini, F.S.2
Reaven, G.M.3
|