Targeting EP4 by curcumin through cross talks of AMP-dependent kinase alpha and p38 mitogen-activated protein kinase signaling: The role of PGC-1α and Sp1

Cellular Signalling

Volumn 25, Issue 12, 2013, Pages 2566-2574

  Hann, Swei Sunny ^a   Chen, Jianping ^b   Wang, Zhiyu ^b   Wu, JingJing ^a   Zheng, Fang ^a   Zhao, ShunYu ^a  

^a GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

^b THE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

AMPK p38 MAPK; Curcumin; EP4; Head and neck cancer cells; PGC 1 ; Sp1

Indexed keywords

4 [4 (4 FLUOROPHENYL) 5 (2 METHOXY 4 PYRIMIDINYL) 1 IMIDAZOLYL]CYCLOHEXANOL; ADENOSINE PHOSPHATE; AMP DEPENDENT KINASE ALPHA; CURCUMIN; METFORMIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E RECEPTOR 4; PROTEIN SERINE THREONINE KINASE; SMALL INTERFERING RNA; SP1 PROTEIN; UNCLASSIFIED DRUG; ADENYLATE KINASE; ANTINEOPLASTIC AGENT; PPARGC1A PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ARTICLE; CANCER CELL; CANCER INHIBITION; CONTROLLED STUDY; DRUG TARGETING; ENZYME INHIBITION; EP4 GENE; GENE EXPRESSION; GENE OVEREXPRESSION; GENE SILENCING; HEAD AND NECK CANCER; HUMAN; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; CELL PROLIFERATION; DOWN REGULATION; DRUG EFFECTS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENETICS; HEAD AND NECK NEOPLASMS; METABOLISM; MOLECULARLY TARGETED THERAPY; PATHOLOGY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ADENYLATE KINASE; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CURCUMIN; DOWN-REGULATION; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HEAD AND NECK NEOPLASMS; HUMANS; METFORMIN; MOLECULAR TARGETED THERAPY; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RECEPTORS, PROSTAGLANDIN E, EP4 SUBTYPE; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84884300369     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2013.08.020     Document Type: Article

References (44)

1. Rahman M.A., Amin A.R., Shin D.M. Nutr. Cancer 2010, 62:973-987.
2. Chen A.Y., DeSantis C., Jemal A. Arch. Otolaryngol. Head Neck Surg. 2011, 137:1094-1099.
3. Aggarwal B.B., Sundaram C., Malani N., Ichikawa H. Adv. Exp. Med. Biol. 2007, 595:1-75.
4. Wilken R., Veena M.S., Wang M.B., Srivatsan E.S. Mol. Cancer 2011, 10:12.
5. Zheng Y., Ritzenthaler J.D., Sun X., Roman J., Han S. Cancer Res. 2009, 69:896-904.
6. Zhang Y., Daaka Y. Blood 2011, 118:5355-5364.
7. Rasmuson A., Kock A., Fuskevag O.M., Kruspig B., Simon-Santamaria J., Gogvadze V., Johnsen J.I., Kogner P., Sveinbjornsson B. PLoS One 2012, 7:e29331.
8. Xia D., Wang D., Kim S.H., Katoh H., DuBois R.N. Nat. Med. 2012, 18:224-226.
9. Fulton A.M., Ma X., Kundu N. Cancer Res. 2006, 66:9794-9797.
10. Schauer M., Peiper M., Theisen J., Knoefel W. Eur. J. Med. Res. 2011, 16:29-33.
11. Iwanaga K., Okada M., Murata T., Hori M., Ozaki H. J. Pharmacol. Exp. Ther. 2012, 340:604-611.
12. Abrahao A.C., Castilho R.M., Squarize C.H., Molinolo A.A., dos Santos-Pinto D., Gutkind J.S. Oral Oncol. 2010, 46:880-887.
13. Kambe A., Iguchi G., Moon Y., Kamitani H., Watanabe T., Eling T.E. Biochim. Biophys. Acta 2008, 1783:1211-1219.
14. Ichida M., Nemoto S., Finkel T. J. Biol. Chem. 2002, 277:50991-50995.
15. Kim J.H., Park J.M., Kim E.K., Lee J.O., Lee S.K., Jung J.H., You G.Y., Park S.H., Suh P.G., Kim H.S. J. Cell. Physiol. 2010, 223:771-778.
16. Pan W., Yang H., Cao C., Song X., Wallin B., Kivlin R., Lu S., Hu G., Di W., Wan Y. Oncol. Rep. 2008, 20:1553-1559.
17. Ayli E.E., Dugas-Breit S., Li W., Marshall C., Zhao L., Meulener M., Griffin T., Gelfand J.M., Seykora J.T. Exp. Dermatol. 2010, 19:493-500.
18. Rechtman M.M., Har-Noy O., Bar-Yishay I., Fishman S., Adamovich Y., Shaul Y., Halpern Z., Shlomai A. FEBS Lett. 2010, 584:2485-2490.
19. Kim J.I., Lakshmikanthan V., Frilot N., Daaka Y. Mol. Can. Res. 2010, 8:569-577.
20. Wang D., Dubois R.N. Gut 2006, 55:115-122.
21. Oshima H., Hioki K., Popivanova B.K., Oguma K., Van Rooijen N., Ishikawa T.O., Oshima M. Gastroenterology 2011, 140:596-607. e597.
22. Jung I.D., Jeong Y.I., Lee C.M., Noh K.T., Jeong S.K., Chun S.H., Choi O.H., Park W.S., Han J., Shin Y.K., Kim H.W., Yun C.H., Park Y.M. Int. Immunopharmacol. 2010, 10:760-768.
23. Moriyuki K., Sekiguchi F., Matsubara K., Nishikawa H., Kawabata A. J. Pharmacol. Sci. 2010, 114:225-229.
24. Hai L., Kawarabayashi Y., Imai Y., Honda A., Inoue R. Am. J. Physiol. Gastrointest. Liver Physiol. 2011, 301:G356-367.
25. Lev-Ari S., Maimon Y., Strier L., Kazanov D., Arber N. J. Soc. Integr. Oncol. 2006, 4:21-26.
26. Tang Y., Chen A. Endocrinology 2010, 151:4168-4177.
27. Thomas S.L., Zhao J., Li Z., Lou B., Du Y., Purcell J., Snyder J.P., Khuri F.R., Liotta D., Fu H. Biochem. Pharmacol. 2010, 80:1309-1316.
28. Wu S.H., Hang L.W., Yang J.S., Chen H.Y., Lin H.Y., Chiang J.H., Lu C.C., Yang J.L., Lai T.Y., Ko Y.C., Chung J.G. Anticancer. Res. 2010, 30:2125-2133.
29. Chang K.W., Hung P.S., Lin I.Y., Hou C.P., Chen L.K., Tsai Y.M., Lin S.C. Int. J. Cancer 2010, 127:9-20.
30. Bae C.H., Kim J.W., Ye S.B., Song S.Y., Kim Y.W., Park S.Y., Kim Y.D. Biochem. Biophys. Res. Commun. 2011, 409:669-674.
31. Wu N., Gu C., Gu H., Hu H., Han Y., Li Q. Neoplasma 2011, 58:482-490.
32. Tseng S.C., Huang Y.C., Chen H.J., Chiu H.C., Huang Y.J., Wo T.Y., Weng S.H., Lin Y.W. Biochem. Pharmacol. 2013, 85:583-594.
33. Liang H.L., Dhar S.S., Wong-Riley M.T. J. Neurosci. Res. 2010, 88:640-649.
34. Pogozelski A.R., Geng T., Li P., Yin X., Lira V.A., Zhang M., Chi J.T., Yan Z. PLoS One 2009, 4:e7934.
35. Smith B.K., Mukai K., Lally J.S., Maher A.C., Gurd B.J., Heigenhauser G.J., Spriet L.L., Holloway G.P. J. Physiol. 2013, 591:1551-1561.
36. Kukidome D., Nishikawa T., Sonoda K., Imoto K., Fujisawa K., Yano M., Motoshima H., Taguchi T., Matsumura T., Araki E. Diabetes 2006, 55:120-127.
37. Puigserver P., Spiegelman B.M. Endocr. Rev. 2003, 24:78-90.
38. Palikhe N.S., Sin H.J., Kim S.H., Hwang E.K., Ye Y.M., Park H.S. J. Hum. Genet. 2012, 57:494-499.
39. Wang L., Guan X., Zhang J., Jia Z., Wei D., Li Q., Yao J., Xie K. Int. J. Oncol. 2008, 33:161-167.
40. Gandhy S.U., Kim K., Larsen L., Rosengren R.J., Safe S. BMC Cancer 2012, 12:564.
41. Logotheti S., Michalopoulos I., Sideridou M., Daskalos A., Kossida S., Spandidos D.A., Field J.K., Vojtesek B., Liloglou T., Gorgoulis V., Zoumpourlis V. FEBS J. 2010, 277:3014-3027.
42. Willoughby J.A., Sundar S.N., Cheung M., Tin A.S., Modiano J., Firestone G.L. J. Biol. Chem. 2009, 284:2203-2213.
43. Deniaud E., Baguet J., Chalard R., Blanquier B., Brinza L., Meunier J., Michallet M.C., Laugraud A., Ah-Soon C., Wierinckx A., Castellazzi M., Lachuer J., Gautier C., Marvel J., Leverrier Y. PLoS One 2009, 4:e7035.
44. Shiota M., Yokomizo A., Tada Y., Inokuchi J., Tatsugami K., Kuroiwa K., Uchiumi T., Fujimoto N., Seki N., Naito S. Mol. Endocrinol. 2010, 24:114-127.