메뉴 건너뛰기




Volumn 417, Issue 3, 2012, Pages 1074-1079

RAS oncogenic signal upregulates EZH2 in pancreatic cancer

Author keywords

EZH2; Pancreatic cancer; RAS; RUNX3

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MUTANT PROTEIN; RAS PROTEIN; TRANSCRIPTION FACTOR ELK 1; TRANSCRIPTION FACTOR EZH2; TRANSCRIPTION FACTOR RUNX3;

EID: 84855989975     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.12.099     Document Type: Article
Times cited : (32)

References (20)
  • 1
    • 0019193408 scopus 로고
    • Scolnick EM: Guanine nucleotide-binding and autophosphorylating activities associated with the p21src protein of Harvey murine sarcoma virus
    • Shih T.Y., Papageorge A.G., Stokes P.E., Weeks M.O. Scolnick EM: Guanine nucleotide-binding and autophosphorylating activities associated with the p21src protein of Harvey murine sarcoma virus. Nature 1980, 287:686-691.
    • (1980) Nature , vol.287 , pp. 686-691
    • Shih, T.Y.1    Papageorge, A.G.2    Stokes, P.E.3    Weeks, M.O.4
  • 2
    • 33847084602 scopus 로고    scopus 로고
    • Cavalli G: Genome regulation by polycomb and trithorax proteins
    • Schuettengruber B., Chourrout D., Vervoort M., Leblanc B. Cavalli G: Genome regulation by polycomb and trithorax proteins. Cell 2007, 128:735-745.
    • (2007) Cell , vol.128 , pp. 735-745
    • Schuettengruber, B.1    Chourrout, D.2    Vervoort, M.3    Leblanc, B.4
  • 6
    • 41349104897 scopus 로고    scopus 로고
    • Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells
    • Fujii S., Ochiai A. Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells. Cancer Sci. 2008, 99:738-746.
    • (2008) Cancer Sci. , vol.99 , pp. 738-746
    • Fujii, S.1    Ochiai, A.2
  • 7
    • 47749134140 scopus 로고    scopus 로고
    • Enhancer of zeste homologue 2 (EZH2) down-regulates RUNX3 by increasing histone H3 methylation
    • Fujii S., Ito K., Ito Y., Ochiai A. Enhancer of zeste homologue 2 (EZH2) down-regulates RUNX3 by increasing histone H3 methylation. J. Biol. Chem. 2008, 283:17324-17332.
    • (2008) J. Biol. Chem. , vol.283 , pp. 17324-17332
    • Fujii, S.1    Ito, K.2    Ito, Y.3    Ochiai, A.4
  • 8
    • 70349238717 scopus 로고    scopus 로고
    • Targeted overexpression of EZH2 in the mammary gland disrupts ductal morphogenesis and causes epithelial hyperplasia
    • Li X., Gonzalez M.E., Toy K., Filzen T., Merajver S.D., Kleer C.G. Targeted overexpression of EZH2 in the mammary gland disrupts ductal morphogenesis and causes epithelial hyperplasia. Am. J. Pathol. 2009, 175:1246-1254.
    • (2009) Am. J. Pathol. , vol.175 , pp. 1246-1254
    • Li, X.1    Gonzalez, M.E.2    Toy, K.3    Filzen, T.4    Merajver, S.D.5    Kleer, C.G.6
  • 9
    • 33646267689 scopus 로고    scopus 로고
    • Identification of EZH2 as a molecular marker for a precancerous state in morphologically normal breast tissues
    • Ding L., Erdmann C., Chinnaiyan A.M., Merajver S.D., Kleer C.G. Identification of EZH2 as a molecular marker for a precancerous state in morphologically normal breast tissues. Cancer Res. 2006, 66:4095-4099.
    • (2006) Cancer Res. , vol.66 , pp. 4095-4099
    • Ding, L.1    Erdmann, C.2    Chinnaiyan, A.M.3    Merajver, S.D.4    Kleer, C.G.5
  • 10
    • 85027937746 scopus 로고    scopus 로고
    • MEK-ERK pathway regulates EZH2 overexpression in association with aggressive breast cancer subtypes
    • Fujii S., Tokita K., Wada N., Ito K., Yamauchi C., Ito Y., Ochiai A. MEK-ERK pathway regulates EZH2 overexpression in association with aggressive breast cancer subtypes. Oncogene 2011, 30:4118-4128.
    • (2011) Oncogene , vol.30 , pp. 4118-4128
    • Fujii, S.1    Tokita, K.2    Wada, N.3    Ito, K.4    Yamauchi, C.5    Ito, Y.6    Ochiai, A.7
  • 15
    • 10744223629 scopus 로고    scopus 로고
    • Reactivation of the silenced and imprinted alleles of ARHI is associated with increased histone H3 acetylation and decreased histone H3 lysine 9 methylation
    • Fujii S., Luo R.Z., Yuan J., Kadota M., Oshimura M., Dent S.R., Kondo Y., Issa J.P., Bast R.C., Yu Y. Reactivation of the silenced and imprinted alleles of ARHI is associated with increased histone H3 acetylation and decreased histone H3 lysine 9 methylation. Hum. Mol. Genet. 2003, 12:1791-1800.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 1791-1800
    • Fujii, S.1    Luo, R.Z.2    Yuan, J.3    Kadota, M.4    Oshimura, M.5    Dent, S.R.6    Kondo, Y.7    Issa, J.P.8    Bast, R.C.9    Yu, Y.10
  • 16
    • 62249151768 scopus 로고    scopus 로고
    • Runx3 expression in gastrointestinal tract epithelium: resolving the controversy
    • Ito K., Inoue K.I., Bae S.C., Ito Y. Runx3 expression in gastrointestinal tract epithelium: resolving the controversy. Oncogene 2009, 28:1379-1384.
    • (2009) Oncogene , vol.28 , pp. 1379-1384
    • Ito, K.1    Inoue, K.I.2    Bae, S.C.3    Ito, Y.4
  • 17
    • 0029787957 scopus 로고    scopus 로고
    • An effect of KRAS gene mutation on epidermal growth factor receptor signal transduction in PANC-1 pancreatic carcinoma cells
    • Watanabe M., Nobuta A., Tanaka J., Asaka M. An effect of KRAS gene mutation on epidermal growth factor receptor signal transduction in PANC-1 pancreatic carcinoma cells. Int. J. Cancer 1996, 67:264-268.
    • (1996) Int. J. Cancer , vol.67 , pp. 264-268
    • Watanabe, M.1    Nobuta, A.2    Tanaka, J.3    Asaka, M.4
  • 18
    • 0037264633 scopus 로고    scopus 로고
    • Targeting RAS signalling pathways in cancer therapy
    • Downward J. Targeting RAS signalling pathways in cancer therapy. Nat. Rev. Cancer 2003, 3:11-22.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 11-22
    • Downward, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.