Baicalein reduces the invasion of glioma cells via reducing the activity of P38 signaling pathway

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Zhang, Zhenni ^a   Lv, Jianrui ^a   Lei, Xiaoming ^a   Li, Siyuan ^a   Zhang, Yong ^a   Meng, Lihua ^a   Xue, Rongliang ^a   Li, Zongfang ^a,b  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b the Second Affiliated Hospital   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BAICALEIN; GELATINASE A; GELATINASE B; JANUS KINASE 1; JANUS KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL MOTILITY; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GLIOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SIGNALING; MIGRATION INHIBITION; PROTEIN EXPRESSION; TUMOR INVASION; UPREGULATION;

ANISOMYCIN; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CELL MOVEMENT; DRUG SYNERGISM; FLAVANONES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMIDAZOLES; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICROGLIA; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PLANT EXTRACTS; PROTEIN KINASE INHIBITORS; PYRIDINES; SCUTELLARIA BAICALENSIS; SIGNAL TRANSDUCTION; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASE-2;

EID: 84896528654     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0090318     Document Type: Article

References (41)

1. Wei J, Gabrusiewicz K, Heimberger A (2013) The controversial role of microglia in malignant gliomas. Clinical & developmental immunology 2013: 285246.
2. Kettenmann H, Hanisch UK, Noda M, Verkhratsky A (2011) Physiology of microglia. Physiological reviews 91: 461-553.
3. Ricard D, Idbaih A, Ducray F, Lahutte M, Hoang-Xuan K, et al. (2012) Primary brain tumours in adults. Lancet 379: 1984-1996.
4. Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, et al. (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. The New England journal of medicine 352: 987-996. (Pubitemid 40349501)
5. Stupp R, Hegi ME, Mason WP, van den Bent MJ, Taphoorn MJ, et al. (2009) Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. The lancet oncology 10: 459-466.
6. Rock K, McArdle O, Forde P, Dunne M, Fitzpatrick D, et al. (2012) A clinical review of treatment outcomes in glioblastoma multiforme-the validation in a non-trial population of the results of a randomised Phase III clinical trial: has a more radical approach improved survival? The British journal of radiology 85: e729-733.
7. Kumar A, El-Osta A, Hussain AA, Marshall J (2010) Increased sequestration of matrix metalloproteinases in ageing human Bruch's membrane: implications for ECM turnover. Investigative ophthalmology & visual science 51: 2664-2670.
8. Gialeli C, Theocharis AD, Karamanos NK (2011) Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting. The FEBS journal 278: 16-27.
9. Iguchi K (2012) [Effect of bisphosphonates on anticancer activity in prostate cancer cells]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 132: 1025-1030.
10. Rubaci AH, Kazancioglu HO, Olgac V, Ak G (2012) The roles of matrix metalloproteinases-2, -7, -10 and tissue inhibitor of metalloproteinase-1 in the pathogenesis of oral lichen planus. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 41: 689-696.
11. Okada A (1999) [Roles of matrix metalloproteinases and tissue inhibitor of metalloproteinase (TIMP) in cancer invasion and metastasis]. Gan to kagaku ryoho Cancer & chemotherapy 26: 2247-2252.
12. Murphy G (2011) Tissue inhibitors of metalloproteinases. Genome biology 12: 233.
13. Chang L, Karin M (2001) Mammalian MAP kinase signalling cascades. Nature 410: 37-40. (Pubitemid 32225829)
14. Woo JS, Kim SM, Jeong CH, Ryu CH, Jeun SS (2013) Lipoxygenase inhibitor MK886 potentiates TRAIL-induced apoptosis through CHOP- and p38 MAPK-mediated up-regulation of death receptor 5 in malignant glioma. Biochemical and biophysical research communications 431: 354-359.
15. Kim SM, Park JG, Baek WK, Suh MH, Lee H, et al. (2008) Cadmium specifically induces MKP-1 expression via the glutathione depletion-mediated p38 MAPK activation in C6 glioma cells. Neuroscience letters 440: 289-293.
16. Posser T, de Aguiar CB, Garcez RC, Rossi FM, Oliveira CS, et al. (2007) Exposure of C6 glioma cells to Pb(II) increases the phosphorylation of p38(MAPK) and JNK1/2 but not of ERK1/2. Archives of toxicology 81: 407-414. (Pubitemid 46991725)
17. Yoshino Y, Aoyagi M, Tamaki M, Duan L, Morimoto T, et al. (2006) Activation of p38 MAPK and/or JNK contributes to increased levels of VEGF secretion in human malignant glioma cells. International journal of oncology 29: 981-987.
18. Ahn HC, Lee SY, Kim JW, Son WS, Shin CG, et al. (2001) Binding aspects of baicalein to HIV-1 integrase. Molecules and cells 12: 127-130.
19. Huang WH, Lee AR, Chien PY, Chou TC (2005) Synthesis of baicalein derivatives as potential anti-aggregatory and anti-inflammatory agents. The Journal of pharmacy and pharmacology 57: 219-225.
20. Hwang JM, Tseng TH, Tsai YY, Lee HJ, Chou FP, et al. (2005) Protective effects of baicalein on tert-butyl hydroperoxide-induced hepatic toxicity in rat hepatocytes. Journal of biomedical science 12: 389-397.
21. Ma Y, Yu WD, Trump DL, Johnson CS (2010) 1,25D3 enhances antitumor activity of gemcitabine and cisplatin in human bladder cancer models. Cancer 116: 3294-3303.
22. Liu B, Wang G, Yang J, Pan X, Yang Z, et al. (2011) Berberine inhibits human hepatoma cell invasion without cytotoxicity in healthy hepatocytes. PloS one 6: e21416.
23. Yang SF, Yang WE, Kuo WH, Chang HR, Chu SC, et al. (2008) Antimetastatic potentials of flavones on oral cancer cell via an inhibition of matrix-degrading proteases. Archives of oral biology 53: 287-294.
24. Rota R, Yeh C-B, Hsieh M-J, Hsieh Y-H, Chien M-H, et al. (2012) Antimetastatic Effects of Norcantharidin on Hepatocellular Carcinoma by Transcriptional Inhibition of MMP-9 through Modulation of NF-kB Activity. PLoS ONE 7: e31055.
25. Ahmed AU, Auffinger B, Lesniak MS (2013) Understanding glioma stem cells: rationale, clinical relevance and therapeutic strategies. Expert review of neurotherapeutics 13: 545-555.
26. Wisniewski P, Ellert-Miklaszewska A, Kwiatkowska A, Kaminska B (2010) Nonapoptotic Fas signaling regulates invasiveness of glioma cells and modulates MMP-2 activity via NFkappaB-TIMP-2 pathway. Cellular signalling 22: 212-220.
27. Sun C, Wang Q, Zhou H, Yu S, Simard AR, et al. (2013) Antisense MMP-9 RNA inhibits malignant glioma cell growth in vitro and in vivo. Neuroscience bulletin 29: 83-93.
28. Demuth T, Reavie LB, Rennert JL, Nakada M, Nakada S, et al. (2007) MAP-ing glioma invasion: mitogen-activated protein kinase kinase 3 and p38 drive glioma invasion and progression and predict patient survival. Molecular cancer therapeutics 6: 1212-1222. (Pubitemid 46711984)
29. Wang ZS, Luo P, Dai SH, Liu ZB, Zheng XR, et al. (2013) Salvianolic Acid B Induces Apoptosis in Human Glioma U87 Cells Through p38-Mediated ROS Generation. Cellular and molecular neurobiology.
30. Wu Y, Zhu L, Liu L, Zhang J, Peng B (2013) Interleukin-17A increases cell migration and MMP-1 expression in human periodontal ligament fibroblasts via p38 MAPK/NF-kappaB -dependent pathway. Journal of cellular physiology.
31. Mondal S, Bandyopadhyay S, Ghosh MK, Mukhopadhyay S, Roy S, et al. (2012) Natural products: promising resources for cancer drug discovery. Anticancer agents in medicinal chemistry 12: 49-75.
32. Chandrashekar N, Selvamani A, Subramanian R, Pandi A, Thiruvengadam D (2012) Baicalein inhibits pulmonary carcinogenesis-associated inflammation and interferes with COX-2, MMP-2 and MMP-9 expressions in-vivo. Toxicology and applied pharmacology 261: 10-21.
33. Wu B, Li J, Huang D, Wang W, Chen Y, et al. (2011) Baicalein mediates inhibition of migration and invasiveness of skin carcinoma through Ezrin in A431 cells. BMC Cancer 11: 527.
34. Wang ZD, Huang C, Li ZF, Yang J, Li BH, et al. (2010) Chrysanthemum indicum ethanolic extract inhibits invasion of hepatocellular carcinoma via regulation of MMP/TIMP balance as therapeutic target. Oncology reports 23: 413-421.
35. Itoh Y, Nagase H (2002) Matrix metalloproteinases in cancer. Essays in biochemistry 38: 21-36. (Pubitemid 36589192)
36. Yang SF, Chen MK, Hsieh YS, Yang JS, Zavras AI, et al. (2010) Antimetastatic effects of Terminalia catappa L. on oral cancer via a down-regulation of metastasis-associated proteases. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 48: 1052-1058.
37. Weng CJ, Chau CF, Hsieh YS, Yang SF, Yen GC (2008) Lucidenic acid inhibits PMA-induced invasion of human hepatoma cells through inactivating MAPK/ ERK signal transduction pathway and reducing binding activities of NF-kappaB and AP-1. Carcinogenesis 29: 147-156.
38. Chen K, Zhang S, Ji Y, Li J, An P, et al. (2013) Baicalein Inhibits the Invasion and Metastatic Capabilities of Hepatocellular Carcinoma Cells via Down-Regulation of the ERK Pathway. PLoS One 8: e72927.
39. Cohen M, Meisser A, Haenggeli L, Bischof P (2006) Involvement of MAPK pathway in TNF-alpha-induced MMP-9 expression in human trophoblastic cells. Molecular human reproduction 12: 225-232. (Pubitemid 43779073)
40. Bradham C, McClay DR (2006) p38 MAPK in development and cancer. Cell cycle 5: 824-828. (Pubitemid 44145574)
41. Acha O, Hernandez JL, Penado S, Cano M, Riancho JA (2003) [Risk factors and stroke among patients of different ages]. Revista clinica espanola 203: 189-192. (Pubitemid 36656554)