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Volumn 7, Issue 1, 2014, Pages 239-244

hTERT promoter activity identifies osteosarcoma cells with increased EMT characteristics

Author keywords

Epithelial mesenchymal transition; Human telomerase reverse transcriptase; Osteosarcoma; Telomerase

Indexed keywords

LENTIVIRUS VECTOR; TELOMERASE REVERSE TRANSCRIPTASE; VIMENTIN;

EID: 84888413145     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2013.1692     Document Type: Article
Times cited : (26)

References (31)
  • 1
    • 79955086282 scopus 로고    scopus 로고
    • Using epidemiology and genomics to understand osteosarcoma etiology
    • Savage SA and Mirabello L: Using epidemiology and genomics to understand osteosarcoma etiology. Sarcoma 2011: 548151, 2011.
    • (2011) Sarcoma , vol.2011 , pp. 548151
    • Savage, S.A.1    Mirabello, L.2
  • 2
    • 63449118087 scopus 로고    scopus 로고
    • Osteosarcoma incidence and survival rates from 1973 to 2004: Data from the Surveillance, Epidemiology, and End Results Program
    • Mirabello L, Troisi RJ and Savage SA: Osteosarcoma incidence and survival rates from 1973 to 2004: data from the Surveillance, Epidemiology, and End Results Program. Cancer 115: 1531-1543, 2009.
    • (2009) Cancer , vol.115 , pp. 1531-1543
    • Mirabello, L.1    Troisi, R.J.2    Savage, S.A.3
  • 3
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • Kalluri R and Weinberg RA: The basics of epithelial-mesenchymal transition. J Clin Invest 119: 1420-1428, 2009.
    • (2009) J Clin Invest , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 4
    • 84873050284 scopus 로고    scopus 로고
    • Regulatory networks defining EMT during cancer initiation and progression
    • De Craene B and Berx G: Regulatory networks defining EMT during cancer initiation and progression. Nat Rev Cancer 13: 97-110, 2013.
    • (2013) Nat Rev Cancer , vol.13 , pp. 97-110
    • De Craene, B.1    Berx, G.2
  • 5
    • 84862333338 scopus 로고    scopus 로고
    • EMT in carcinoma progression and dissemination: Facts, unanswered questions, and clinical considerations
    • Bastid J: EMT in carcinoma progression and dissemination: facts, unanswered questions, and clinical considerations. Cancer Metastasis Rev 31: 277-283, 2012.
    • (2012) Cancer Metastasis Rev , vol.31 , pp. 277-283
    • Bastid, J.1
  • 6
    • 77956178360 scopus 로고    scopus 로고
    • EMT, cancer stem cells and drug resistance: An emerging axis of evil in the war on cancer
    • Singh A and Settleman J: EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer. Oncogene 29: 4741-4751, 2010.
    • (2010) Oncogene , vol.29 , pp. 4741-4751
    • Singh, A.1    Settleman, J.2
  • 7
    • 84860389952 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and cancer stem cells: A dangerously dynamic duo in breast cancer progression
    • May CD, Sphyris N, Evans KW, Werden SJ, Guo W and Mani SA: Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression. Breast Cancer Res 13: 202, 2011.
    • (2011) Breast Cancer Res , vol.13 , pp. 202
    • May, C.D.1    Sphyris, N.2    Evans, K.W.3    Werden, S.J.4    Guo, W.5    Mani, S.A.6
  • 8
  • 9
    • 0029114679 scopus 로고
    • Telomeres and telomerase in human cancer (review)
    • Bacchetti S and Counter C: Telomeres and telomerase in human cancer (review). Int J Oncol 7: 423-432, 1995.
    • (1995) Int J Oncol , vol.7 , pp. 423-432
    • Bacchetti, S.1    Counter, C.2
  • 10
    • 0033932489 scopus 로고    scopus 로고
    • Role of telomerase in normal and cancer cells
    • Meyerson M: Role of telomerase in normal and cancer cells. J Clin Oncol 18: 2626-2634, 2000.
    • (2000) J Clin Oncol , vol.18 , pp. 2626-2634
    • Meyerson, M.1
  • 11
    • 84867808311 scopus 로고    scopus 로고
    • Telomere structure and telomerase in health and disease (review)
    • Gomez DE, Armando RG, Farina HG, et al: Telomere structure and telomerase in health and disease (review). Int J Oncol 41: 1561-1569, 2012.
    • (2012) Int J Oncol , vol.41 , pp. 1561-1569
    • Gomez, D.E.1    Armando, R.G.2    Farina, H.G.3
  • 12
    • 0028564951 scopus 로고
    • Specific association of human telomerase activity with immortal cells and cancer
    • Kim NW, Piatyszek MA, Prowse KR, et al: Specific association of human telomerase activity with immortal cells and cancer. Science 266: 2011-2015, 1994.
    • (1994) Science , vol.266 , pp. 2011-2015
    • Kim, N.W.1    Piatyszek, M.A.2    Prowse, K.R.3
  • 14
    • 0031010342 scopus 로고    scopus 로고
    • A survey of telomerase activity in human cancer
    • Shay JW and Bacchetti S: A survey of telomerase activity in human cancer. Eur J Cancer 33: 787-791, 1997.
    • (1997) Eur J Cancer , vol.33 , pp. 787-791
    • Shay, J.W.1    Bacchetti, S.2
  • 15
    • 0035097792 scopus 로고    scopus 로고
    • Immunohistochemical detection of telomerase (hTERT) protein in human cancer tissues and a subset of cells in normal tissues
    • Hiyama E, Hiyama K, Yokoyama T and Shay JW: Immunohistochemical detection of telomerase (hTERT) protein in human cancer tissues and a subset of cells in normal tissues. Neoplasia 3: 17-26, 2001.
    • (2001) Neoplasia , vol.3 , pp. 17-26
    • Hiyama, E.1    Hiyama, K.2    Yokoyama, T.3    Shay, J.W.4
  • 16
    • 84883743387 scopus 로고    scopus 로고
    • Telomerase reverse transcriptase promotes epithelial-mesenchymal transition and stem cell-like traits in cancer cells
    • Liu Z, Li Q, Li K, et al: Telomerase reverse transcriptase promotes epithelial-mesenchymal transition and stem cell-like traits in cancer cells. Oncogene 32: 4203-4213, 2013.
    • (2013) Oncogene , vol.32 , pp. 4203-4213
    • Liu, Z.1    Li, Q.2    Li, K.3
  • 17
    • 0033577876 scopus 로고    scopus 로고
    • Genomic organization and promoter characterization of the gene encoding the human telomerase reverse transcriptase (hTERT)
    • Wick M, Zubov D and Hagen G: Genomic organization and promoter characterization of the gene encoding the human telomerase reverse transcriptase (hTERT). Gene 232: 97-106, 1999.
    • (1999) Gene , vol.232 , pp. 97-106
    • Wick, M.1    Zubov, D.2    Hagen, G.3
  • 18
    • 0033082526 scopus 로고    scopus 로고
    • Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells
    • Takakura M, Kyo S, Kanaya T, et al: Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells. Cancer Res 59: 551-557, 1999.
    • (1999) Cancer Res , vol.59 , pp. 551-557
    • Takakura, M.1    Kyo, S.2    Kanaya, T.3
  • 19
    • 0032962953 scopus 로고    scopus 로고
    • The human telomerase catalytic subunit hTERT: Organization of the gene and characterization of the promoter
    • Cong YS, Wen J and Bacchetti S: The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter. Hum Mol Genet 8: 137-142, 1999.
    • (1999) Hum Mol Genet , vol.8 , pp. 137-142
    • Cong, Y.S.1    Wen, J.2    Bacchetti, S.3
  • 20
    • 78549268818 scopus 로고    scopus 로고
    • Silencing of autocrine motility factor induces mesenchymal-to-epithelial transition and suppression of osteosarcoma pulmonary metastasis
    • Niinaka Y, Harada K, Fujimuro M, et al: Silencing of autocrine motility factor induces mesenchymal-to-epithelial transition and suppression of osteosarcoma pulmonary metastasis. Cancer Res 70: 9483-9493, 2010.
    • (2010) Cancer Res , vol.70 , pp. 9483-9493
    • Niinaka, Y.1    Harada, K.2    Fujimuro, M.3
  • 21
    • 34249315460 scopus 로고    scopus 로고
    • Down-regulation of phosphoglucose isomerase/autocrine motility factor results in mesenchymal-to-epithelial transition of human lung fibrosarcoma cells
    • Funasaka T, Hu H, Yanagawa T, Hogan V and Raz A: Down-regulation of phosphoglucose isomerase/autocrine motility factor results in mesenchymal-to-epithelial transition of human lung fibrosarcoma cells. Cancer Res 67: 4236-4243, 2007.
    • (2007) Cancer Res , vol.67 , pp. 4236-4243
    • Funasaka, T.1    Hu, H.2    Yanagawa, T.3    Hogan, V.4    Raz, A.5
  • 22
    • 67650463104 scopus 로고    scopus 로고
    • Phosphoglucose isomerase/autocrine motility factor mediates epithelial and mesenchymal phenotype conversions in breast cancer
    • Funasaka T, Hogan V and Raz A: Phosphoglucose isomerase/autocrine motility factor mediates epithelial and mesenchymal phenotype conversions in breast cancer. Cancer Res 69: 5349-5356, 2009.
    • (2009) Cancer Res , vol.69 , pp. 5349-5356
    • Funasaka, T.1    Hogan, V.2    Raz, A.3
  • 24
    • 0037039716 scopus 로고    scopus 로고
    • hTERT gene dosage correlates with telomerase activity in human lung cancer cell lines
    • Saretzki G, Petersen S, Petersen I, Kolble K and von Zglinicki T: hTERT gene dosage correlates with telomerase activity in human lung cancer cell lines. Cancer Lett 176: 81-91, 2002.
    • (2002) Cancer Lett , vol.176 , pp. 81-91
    • Saretzki, G.1    Petersen, S.2    Petersen, I.3    Kolble, K.4    von Zglinicki, T.5
  • 25
    • 0031747370 scopus 로고    scopus 로고
    • Expression of human telomerase subunits and correlation with telomerase activity in urothelial cancer
    • Ito H, Kyo S, Kanaya T, Takakura M, Inoue M and Namiki M: Expression of human telomerase subunits and correlation with telomerase activity in urothelial cancer. Clin Cancer Res 4: 1603-1608, 1998.
    • (1998) Clin Cancer Res , vol.4 , pp. 1603-1608
    • Ito, H.1    Kyo, S.2    Kanaya, T.3    Takakura, M.4    Inoue, M.5    Namiki, M.6
  • 26
    • 79960308407 scopus 로고    scopus 로고
    • Increased telomerase activity and hTERT expression in human salivary gland carcinomas
    • Shigeishi H, Sugiyama M, Tahara H, et al: Increased telomerase activity and hTERT expression in human salivary gland carcinomas. Oncol Lett 2: 845-850, 2011.
    • (2011) Oncol Lett , vol.2 , pp. 845-850
    • Shigeishi, H.1    Sugiyama, M.2    Tahara, H.3
  • 28
    • 77958478367 scopus 로고    scopus 로고
    • Targeting the osteosarcoma cancer stem cell
    • Siclari VA and Qin L: Targeting the osteosarcoma cancer stem cell. J Orthop Surg Res 5: 78, 2010.
    • (2010) J Orthop Surg Res , vol.5 , pp. 78
    • Siclari, V.A.1    Qin, L.2
  • 29
    • 74949143829 scopus 로고    scopus 로고
    • The telomerase antagonist, imetelstat, efficiently targets glioblastoma tumor-initiating cells leading to decreased proliferation and tumor growth
    • Marian CO, Cho SK, McEllin BM, et al: The telomerase antagonist, imetelstat, efficiently targets glioblastoma tumor-initiating cells leading to decreased proliferation and tumor growth. Clin Cancer Res 16: 154-163, 2010.
    • (2010) Clin Cancer Res , vol.16 , pp. 154-163
    • Marian, C.O.1    Cho, S.K.2    McEllin, B.M.3
  • 30
    • 2942601141 scopus 로고    scopus 로고
    • The mRNA expression of hTERT in human breast carcinomas correlates with VEGF expression
    • Kirkpatrick KL, Newbold RF and Mokbel K: The mRNA expression of hTERT in human breast carcinomas correlates with VEGF expression. J Carcinog 3: 1, 2004.
    • (2004) J Carcinog , vol.3 , pp. 1
    • Kirkpatrick, K.L.1    Newbold, R.F.2    Mokbel, K.3
  • 31
    • 67650065306 scopus 로고    scopus 로고
    • Telomerase modulates Wnt signalling by association with target gene chromatin
    • Park JI, Venteicher AS, Hong JY, et al: Telomerase modulates Wnt signalling by association with target gene chromatin. Nature 460: 66-72, 2009.
    • (2009) Nature , vol.460 , pp. 66-72
    • Park, J.I.1    Venteicher, A.S.2    Hong, J.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.