An aqueous extract of Fagonia cretica induces DNA damage, cell cycle arrest and apoptosis in breast cancer cells via FOXO3a and p53 expression

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Lam, Matt ^a   Carmichael, Amtul R ^b   Griffiths, Helen R ^a  

^a ASTON UNIVERSITY   (United Kingdom)

^b DUDLEY GROUP OF HOSPITALS NHS TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CELL DNA; CYCLIN A; FAGONIA CRETICA EXTRACT; HISTONE H2AX; LIPOCORTIN 5; PLANT EXTRACT; PROPIDIUM IODIDE; PROTEIN BAX; PROTEIN P21; PROTEIN P53; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR FKHRL1; UNCLASSIFIED DRUG; WATER;

APOPTOSIS; ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CANCER CELL; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL LABELING; CELL STRAIN; CELL STRAIN MCF 7; CELL STRAIN MDA MB 231; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG TARGETING; EPITHELIUM CELL; FAGONIA CRETICA; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MEDICINAL PLANT; NONHUMAN; PROTEIN EXPRESSION; WILD TYPE;

APOPTOSIS; BREAST NEOPLASMS; CELL CYCLE; CELL LINE, TUMOR; DNA DAMAGE; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; PLANT EXTRACTS; TUMOR SUPPRESSOR PROTEIN P53;

FAGONIA CRETICA;

EID: 84862999175     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040152     Document Type: Article

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