Toll-like receptor 4 senses oxidative stress mediated by the oxidation of phospholipids in extracellular vesicles

Science Signaling

Volumn 8, Issue 381, 2015, Pages ra60-

  Manèek Keber, Mateja ^a,b   Frank Bertoncelj, Mojca ^c   Hafner Bratkoviè, Iva ^a,b   Smole, Anže ^a   Zorko, Mateja ^a   Pirher, Nina ^a   Hayer, Silvia ^d   Kralj Igliè, Veronika ^e   Rozman, Blaž ^c   Ilc, Nejc ^e   Horvat, Simon ^a,e   Jerala, Roman ^a,b  

^a NATIONAL INSTITUTE OF CHEMISTRY   (Slovenia)

^b Centre of Excellence   (Slovenia)

^c UNIVERSITY MEDICAL CENTRE LJUBLJANA   (Slovenia)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

^e UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONATE 15 LIPOXYGENASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; PHOSPHOLIPID; PROTEIN MD 2; TOLL LIKE RECEPTOR 4; LY96 PROTEIN, HUMAN; TLR4 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; DIMERIZATION; EXOSOME; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; INFLAMMATION; MOLECULAR MODEL; MOUSE; MUTATION; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; AGONISTS; DRUG EFFECTS; FEMALE; GENETICS; HEK293 CELL LINE; IMMUNOLOGY; MALE; MEMBRANE MICROPARTICLE; PATHOLOGY; UMBILICAL VEIN ENDOTHELIAL CELL;

PERO;

ARTHRITIS, RHEUMATOID; CELL-DERIVED MICROPARTICLES; FEMALE; HEK293 CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LIPOPOLYSACCHARIDES; LYMPHOCYTE ANTIGEN 96; MALE; OXIDATIVE STRESS; TOLL-LIKE RECEPTOR 4;

EID: 84931062403     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2005860     Document Type: Article

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