CINPA1 is an inhibitor of constitutive androstane receptor that does not activate pregnane X receptors

Molecular Pharmacology

Volumn 87, Issue 5, 2015, Pages 878-889

  Cherian, Milu T ^a   Lin, Wenwei ^a   Wu, Jing ^a   Chen, Taosheng ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAR INHIBITOR NOT PXR ACTIVATOR 1; CLOTRIMAZOLE; CYTOTOXIC AGENT; HORMONE RECEPTOR BLOCKING AGENT; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; PREGNANE X RECEPTOR; RNA POLYMERASE II; UNCLASSIFIED DRUG; XENOBIOTIC AGENT; CARRIER PROTEIN; CELL RECEPTOR; CONSTITUTIVE ANDROSTANE RECEPTOR; MOLECULAR LIBRARY; STEROID RECEPTOR;

ANIMAL CELL; ARTICLE; CELLULAR DISTRIBUTION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG METABOLISM; EMBRYO; GENE EXPRESSION; GENE TARGETING; HEPG2 CELL LINE; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IC50; LIGAND BINDING; LIVER CELL; MOUSE; MULTIGENE FAMILY; NONHUMAN; PRIMARY CELL; PRIORITY JOURNAL; PROMOTER REGION; TRANSACTIVATION; U2OS CELL LINE; ANTAGONISTS AND INHIBITORS; CELL LINE; DRUG EFFECTS; GENETIC TRANSCRIPTION; HEK293 CELL LINE; METABOLISM; MOLECULAR LIBRARY; MULTIDRUG RESISTANCE; PHARMACOLOGY; PROCEDURES; TUMOR CELL LINE; TWO HYBRID SYSTEM;

CELL LINE; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; DRUG RESISTANCE, MULTIPLE; HEK293 CELLS; HEP G2 CELLS; HEPATOCYTES; HUMANS; MEMBRANE TRANSPORT PROTEINS; PROMOTER REGIONS, GENETIC; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; SMALL MOLECULE LIBRARIES; TRANSCRIPTION, GENETIC; TWO-HYBRID SYSTEM TECHNIQUES; XENOBIOTICS;

EID: 84931041071     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.115.097782     Document Type: Article

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