A single amino acid controls the functional switch of human constitutive androstane receptor (CAR) 1 to the xenobiotic-sensitive splicing variant CAR3

Journal of Pharmacology and Experimental Therapeutics

Volumn 332, Issue 1, 2010, Pages 106-115

  Chen, Tao ^a   Tompkins, Leslie M ^a   Li, Linhao ^a   Li, Haishan ^a   Kim, Gregory ^a   Zheng, Yuxin ^b   Wang, Hongbing ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

^b CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

Author keywords

[No Author keywords available]

Indexed keywords

6 (4 CHLOROPHENYL) IMIDAZO[2,1B][1,3]THIAZOLE 5 CARBALDEHYDE O (3,4 DICHLOROBENZYL)OXIME; ALANINE; AMINO ACID; CONSTITUTIVE ANDROSTANE RECEPTOR; CONSTITUTIVE ANDROSTANE RECEPTOR 1; CONSTITUTIVE ANDROSTANE RECEPTOR 3; GLUTATHIONE TRANSFERASE; NUCLEAR RECEPTOR COACTIVATOR 2; OXIME DERIVATIVE; STEROID RECEPTOR COACTIVATOR 1; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

ARTICLE; CELL STRAIN COS1; CELLULAR DISTRIBUTION; CHIMERA; CONTROLLED STUDY; GENETIC VARIABILITY; HEPATOMA CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; PRIORITY JOURNAL; RNA SPLICING;

ALANINE; ALTERNATIVE SPLICING; AMINO ACIDS; ANIMALS; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; CLONING, MOLECULAR; COS CELLS; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; LIGANDS; MUTAGENESIS, SITE-DIRECTED; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TRANSFECTION; TWO-HYBRID SYSTEM TECHNIQUES; XENOBIOTICS;

EID: 73949102632     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.109.159210     Document Type: Article

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