메뉴 건너뛰기




Volumn 384, Issue 2, 2013, Pages 155-165

The human constitutive androstane receptor promotes the differentiation and maturation of hepatic-like cells

Author keywords

CAR; Drug metabolism; Hepatic differentiation; HESCs; Lentivirus; PXR; SiRNA

Indexed keywords

ALBUMIN; CELL NUCLEUS RECEPTOR; CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450 2C9; CYTOCHROME P450 3A4; CYTOCHROME P450 3A7; ENZYME; LENTIVIRUS VECTOR; PLASMA PROTEIN; PREGNANE X RECEPTOR; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR;

EID: 84887617697     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2013.10.012     Document Type: Article
Times cited : (14)

References (56)
  • 1
    • 47949092668 scopus 로고    scopus 로고
    • Efficient differentiation of functional hepatocytes from human embryonic stem cells
    • Agarwal S., Holton K.L., Lanza R. Efficient differentiation of functional hepatocytes from human embryonic stem cells. Stem Cells 2008, 26:1117-1127.
    • (2008) Stem Cells , vol.26 , pp. 1117-1127
    • Agarwal, S.1    Holton, K.L.2    Lanza, R.3
  • 2
    • 33749596610 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells into hepatocytes in 2D and 3D culture systems in vitro
    • Baharvand H., Hashemi S.M., Kazemi A.S., Farrokhi A. Differentiation of human embryonic stem cells into hepatocytes in 2D and 3D culture systems in vitro. Int. J. Dev. Biol. 2006, 50:645-652.
    • (2006) Int. J. Dev. Biol. , vol.50 , pp. 645-652
    • Baharvand, H.1    Hashemi, S.M.2    Kazemi, A.S.3    Farrokhi, A.4
  • 5
    • 54449087431 scopus 로고    scopus 로고
    • C-Myc and its target FoxM1 are critical downstream effectors of constitutive androstane receptor (CAR) mediated direct liver hyperplasia
    • Blanco-Bose W.E., Murphy M.J., Ehninger A., Offner S., Dubey C., Huang W., Moore D.D., Trumpp A. C-Myc and its target FoxM1 are critical downstream effectors of constitutive androstane receptor (CAR) mediated direct liver hyperplasia. Hepatology 2008, 48:1302-1311.
    • (2008) Hepatology , vol.48 , pp. 1302-1311
    • Blanco-Bose, W.E.1    Murphy, M.J.2    Ehninger, A.3    Offner, S.4    Dubey, C.5    Huang, W.6    Moore, D.D.7    Trumpp, A.8
  • 8
    • 33646693667 scopus 로고    scopus 로고
    • Synthetic drugs and natural products as modulators of constitutive androstane receptor (CAR) and pregnane X receptor (PXR)
    • Chang T.K., Waxman D.J. Synthetic drugs and natural products as modulators of constitutive androstane receptor (CAR) and pregnane X receptor (PXR). Drug Metab. Rev. 2006, 38:51-73.
    • (2006) Drug Metab. Rev. , vol.38 , pp. 51-73
    • Chang, T.K.1    Waxman, D.J.2
  • 9
    • 84867185582 scopus 로고    scopus 로고
    • Neonatal activation of the nuclear receptor CAR results in epigenetic memory and permanent change of drug metabolism in mouse liver
    • Chen W.D., Fu X., Dong B., Wang Y.D., Shiah S., Moore D.D., Huang W. Neonatal activation of the nuclear receptor CAR results in epigenetic memory and permanent change of drug metabolism in mouse liver. Hepatology 2012, 56:1499-1509.
    • (2012) Hepatology , vol.56 , pp. 1499-1509
    • Chen, W.D.1    Fu, X.2    Dong, B.3    Wang, Y.D.4    Shiah, S.5    Moore, D.D.6    Huang, W.7
  • 11
    • 55049086868 scopus 로고    scopus 로고
    • Isolation and transcriptional profiling of purified hepatic cells derived from human embryonic stem cells
    • Chiao E., Elazar M., Xing Y., Xiong A., Kmet M., Millan M.T., Glenn J.S., Wong W.H., Baker J. Isolation and transcriptional profiling of purified hepatic cells derived from human embryonic stem cells. Stem Cells 2008, 26:2032-2041.
    • (2008) Stem Cells , vol.26 , pp. 2032-2041
    • Chiao, E.1    Elazar, M.2    Xing, Y.3    Xiong, A.4    Kmet, M.5    Millan, M.T.6    Glenn, J.S.7    Wong, W.H.8    Baker, J.9
  • 15
    • 0242665373 scopus 로고    scopus 로고
    • Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity
    • Guo G.L., Lambert G., Negishi M., Ward J.M., Brewer H.B., Kliewer S.A., Gonzalez F.J., Sinal C.J. Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity. J. Biol. Chem. 2003, 278:45062-45071.
    • (2003) J. Biol. Chem. , vol.278 , pp. 45062-45071
    • Guo, G.L.1    Lambert, G.2    Negishi, M.3    Ward, J.M.4    Brewer, H.B.5    Kliewer, S.A.6    Gonzalez, F.J.7    Sinal, C.J.8
  • 18
    • 79960637387 scopus 로고    scopus 로고
    • Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors
    • Huang P., He Z., Ji S., Sun H., Xiang D., Liu C., Hu Y., Wang X., Hui L. Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors. Nature 2011, 475:386-389.
    • (2011) Nature , vol.475 , pp. 386-389
    • Huang, P.1    He, Z.2    Ji, S.3    Sun, H.4    Xiang, D.5    Liu, C.6    Hu, Y.7    Wang, X.8    Hui, L.9
  • 20
    • 70249090729 scopus 로고    scopus 로고
    • Nuclear receptor regulation of stemness and stem cell differentiation
    • Jeong Y., Mangelsdorf D.J. Nuclear receptor regulation of stemness and stem cell differentiation. Exp. Mol. Med. 2009, 41:525-537.
    • (2009) Exp. Mol. Med. , vol.41 , pp. 525-537
    • Jeong, Y.1    Mangelsdorf, D.J.2
  • 23
    • 33747370376 scopus 로고    scopus 로고
    • Plasticity and expanding complexity of the hepatic transcription factor network during liver development
    • Kyrmizi I., Hatzis P., Katrakili N., Tronche F., Gonzalez F.J., Talianidis I. Plasticity and expanding complexity of the hepatic transcription factor network during liver development. Genes Dev. 2006, 20:2293-2305.
    • (2006) Genes Dev. , vol.20 , pp. 2293-2305
    • Kyrmizi, I.1    Hatzis, P.2    Katrakili, N.3    Tronche, F.4    Gonzalez, F.J.5    Talianidis, I.6
  • 24
    • 9644282186 scopus 로고    scopus 로고
    • Differentiation and isolation of hepatic-like cells from human embryonic stem cells
    • Lavon N., Yanuka O., Benvenisty N. Differentiation and isolation of hepatic-like cells from human embryonic stem cells. Differentiation 2004, 72:230-238.
    • (2004) Differentiation , vol.72 , pp. 230-238
    • Lavon, N.1    Yanuka, O.2    Benvenisty, N.3
  • 25
    • 0034090310 scopus 로고    scopus 로고
    • Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha
    • Li J., Ning G., Duncan S.A. Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha. Genes Dev. 2000, 14:464-474.
    • (2000) Genes Dev. , vol.14 , pp. 464-474
    • Li, J.1    Ning, G.2    Duncan, S.A.3
  • 26
    • 69549088829 scopus 로고    scopus 로고
    • The aldo-keto reductase Akr1b7 gene is a common transcriptional target of xenobiotic receptors pregnane X receptor and constitutive androstane receptor
    • Liu M.J., Takahashi Y., Wada T., He J., Gao J., Tian Y., Li S., Xie W. The aldo-keto reductase Akr1b7 gene is a common transcriptional target of xenobiotic receptors pregnane X receptor and constitutive androstane receptor. Mol. Pharmacol. 2009, 76:604-611.
    • (2009) Mol. Pharmacol. , vol.76 , pp. 604-611
    • Liu, M.J.1    Takahashi, Y.2    Wada, T.3    He, J.4    Gao, J.5    Tian, Y.6    Li, S.7    Xie, W.8
  • 27
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001, 25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 28
    • 2442485772 scopus 로고    scopus 로고
    • The nuclear receptor CAR is a regulator of thyroid hormone metabolism during caloric restriction
    • Maglich J.M., Watson J., McMillen P.J., Goodwin B., Willson T.M., Moore J.T. The nuclear receptor CAR is a regulator of thyroid hormone metabolism during caloric restriction. J. Biol. Chem. 2004, 279:19832-19838.
    • (2004) J. Biol. Chem. , vol.279 , pp. 19832-19838
    • Maglich, J.M.1    Watson, J.2    McMillen, P.J.3    Goodwin, B.4    Willson, T.M.5    Moore, J.T.6
  • 29
    • 28544444942 scopus 로고    scopus 로고
    • Methylation-associated silencing of the nuclear receptor 1I2 gene in advanced-type neuroblastomas, identified by bacterial artificial chromosome array-based methylated CpG island amplification
    • Misawa A., Inoue J., Sugino Y., Hosoi H., Sugimoto T., Hosoda F., Ohki M., Imoto I., Inazawa J. Methylation-associated silencing of the nuclear receptor 1I2 gene in advanced-type neuroblastomas, identified by bacterial artificial chromosome array-based methylated CpG island amplification. Cancer Res. 2005, 65:10233-10242.
    • (2005) Cancer Res. , vol.65 , pp. 10233-10242
    • Misawa, A.1    Inoue, J.2    Sugino, Y.3    Hosoi, H.4    Sugimoto, T.5    Hosoda, F.6    Ohki, M.7    Imoto, I.8    Inazawa, J.9
  • 30
    • 67649873120 scopus 로고    scopus 로고
    • Expedited growth factor-mediated specification of human embryonic stem cells toward the hepatic lineage
    • Moore R.N., Moghe P.V. Expedited growth factor-mediated specification of human embryonic stem cells toward the hepatic lineage. Stem Cell Res. 2009, 3:51-62.
    • (2009) Stem Cell Res. , vol.3 , pp. 51-62
    • Moore, R.N.1    Moghe, P.V.2
  • 31
    • 34250699025 scopus 로고    scopus 로고
    • Gene expression profiling and differentiation assessment in primary human hepatocyte cultures, established hepatoma cell lines, and human liver tissues
    • Olsavsky K.M., Page J.L., Johnson M.C., Zarbl H., Strom S.C., Omiecinski C.J. Gene expression profiling and differentiation assessment in primary human hepatocyte cultures, established hepatoma cell lines, and human liver tissues. Toxicol. Appl. Pharmacol. 2007, 222:42-56.
    • (2007) Toxicol. Appl. Pharmacol. , vol.222 , pp. 42-56
    • Olsavsky, K.M.1    Page, J.L.2    Johnson, M.C.3    Zarbl, H.4    Strom, S.C.5    Omiecinski, C.J.6
  • 32
    • 35448976355 scopus 로고    scopus 로고
    • Regulation of the human cathepsin E gene by the constitutive androstane receptor
    • Page J.L., Strom S.C., Omiecinski C.J. Regulation of the human cathepsin E gene by the constitutive androstane receptor. Arch. Biochem. Biophys. 2007, 467:132-138.
    • (2007) Arch. Biochem. Biophys. , vol.467 , pp. 132-138
    • Page, J.L.1    Strom, S.C.2    Omiecinski, C.J.3
  • 37
    • 48949120846 scopus 로고    scopus 로고
    • Differentiation of mouse and human embryonic stem cells into hepatic lineages
    • Shiraki N., Umeda K., Sakashita N., Takeya M., Kume K., Kume S. Differentiation of mouse and human embryonic stem cells into hepatic lineages. Genes Cells 2008, 13:731-746.
    • (2008) Genes Cells , vol.13 , pp. 731-746
    • Shiraki, N.1    Umeda, K.2    Sakashita, N.3    Takeya, M.4    Kume, K.5    Kume, S.6
  • 38
    • 84876559530 scopus 로고    scopus 로고
    • Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor alpha (PPARalpha) is enhanced by pregnane X receptor (PXR) activation in mice
    • Shizu R., Benoki S., Numakura Y., Kodama S., Miyata M., Yamazoe Y., Yoshinari K. Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor alpha (PPARalpha) is enhanced by pregnane X receptor (PXR) activation in mice. PLoS One 2013, 8:e61802.
    • (2013) PLoS One , vol.8
    • Shizu, R.1    Benoki, S.2    Numakura, Y.3    Kodama, S.4    Miyata, M.5    Yamazoe, Y.6    Yoshinari, K.7
  • 39
    • 65249118823 scopus 로고    scopus 로고
    • In vitro differentiation of embryonic and adult stem cells into hepatocytes: state of the art
    • Snykers S., De Kock J., Rogiers V., Vanhaecke T. In vitro differentiation of embryonic and adult stem cells into hepatocytes: state of the art. Stem Cells 2009, 27:577-605.
    • (2009) Stem Cells , vol.27 , pp. 577-605
    • Snykers, S.1    De Kock, J.2    Rogiers, V.3    Vanhaecke, T.4
  • 40
    • 33746710951 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells to hepatocytes using deleted variant of HGF and poly-amino-urethane-coated nonwoven polytetrafluoroethylene fabric
    • Soto-Gutierrez A., Navarro-Alvarez N., Rivas-Carrillo J.D., Chen Y., Yamatsuji T., Tanaka N., Kobayashi N. Differentiation of human embryonic stem cells to hepatocytes using deleted variant of HGF and poly-amino-urethane-coated nonwoven polytetrafluoroethylene fabric. Cell Transplant. 2006, 15:335-341.
    • (2006) Cell Transplant. , vol.15 , pp. 335-341
    • Soto-Gutierrez, A.1    Navarro-Alvarez, N.2    Rivas-Carrillo, J.D.3    Chen, Y.4    Yamatsuji, T.5    Tanaka, N.6    Kobayashi, N.7
  • 43
    • 3042726385 scopus 로고    scopus 로고
    • CAR, driving into the future
    • Swales K., Negishi M. CAR, driving into the future. Mol. Endocrinol. 2004, 18:1589-1598.
    • (2004) Mol. Endocrinol. , vol.18 , pp. 1589-1598
    • Swales, K.1    Negishi, M.2
  • 44
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126:663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 46
    • 33847024555 scopus 로고    scopus 로고
    • CAR and PXR: the xenobiotic-sensing receptors
    • Timsit Y.E., Negishi M. CAR and PXR: the xenobiotic-sensing receptors. Steroids 2007, 72:231-246.
    • (2007) Steroids , vol.72 , pp. 231-246
    • Timsit, Y.E.1    Negishi, M.2
  • 47
    • 29944436187 scopus 로고    scopus 로고
    • Nuclear receptor expression in fetal and pediatric liver: correlation with CYP3A expression
    • Vyhlidal C.A., Gaedigk R., Leeder J.S. Nuclear receptor expression in fetal and pediatric liver: correlation with CYP3A expression. Drug Metab. Dispos. 2006, 34:131-137.
    • (2006) Drug Metab. Dispos. , vol.34 , pp. 131-137
    • Vyhlidal, C.A.1    Gaedigk, R.2    Leeder, J.S.3
  • 49
    • 0034687397 scopus 로고    scopus 로고
    • The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism
    • Wei P., Zhang J., Egan-Hafley M., Liang S., Moore D.D. The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism. Nature 2000, 407:920-923.
    • (2000) Nature , vol.407 , pp. 920-923
    • Wei, P.1    Zhang, J.2    Egan-Hafley, M.3    Liang, S.4    Moore, D.D.5
  • 50
    • 84887614690 scopus 로고    scopus 로고
    • Cistromes of human CAR reveal novel regulation mechanisms
    • (MON)
    • Xiao R., Ayers S., Moore DD. Cistromes of human CAR reveal novel regulation mechanisms. Endocr. Rev. 2012, 33:536. (MON).
    • (2012) Endocr. Rev. , vol.33 , pp. 536
    • Xiao, R.1    Ayers, S.2    Moore, D.D.3
  • 54
    • 80155177963 scopus 로고    scopus 로고
    • Nuclear receptor CAR (NR1I3) is essential for DDC-induced liver injury and oval cell proliferation in mouse liver
    • Yamazaki Y., Moore R., Negishi M. Nuclear receptor CAR (NR1I3) is essential for DDC-induced liver injury and oval cell proliferation in mouse liver. Lab Invest. 2011, 91:1624-1633.
    • (2011) Lab Invest. , vol.91 , pp. 1624-1633
    • Yamazaki, Y.1    Moore, R.2    Negishi, M.3
  • 55
    • 79952696586 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells along a hepatic lineage
    • Zamule S.M., Coslo D.M., Chen F., Omiecinski C.J. Differentiation of human embryonic stem cells along a hepatic lineage. Chem. Biol. Interact. 2011, 190:62-72.
    • (2011) Chem. Biol. Interact. , vol.190 , pp. 62-72
    • Zamule, S.M.1    Coslo, D.M.2    Chen, F.3    Omiecinski, C.J.4
  • 56
    • 44349133270 scopus 로고    scopus 로고
    • Preservation of hepatic phenotype in lentiviral-transduced primary human hepatocytes
    • Zamule S.M., Strom S.C., Omiecinski C.J. Preservation of hepatic phenotype in lentiviral-transduced primary human hepatocytes. Chem. Biol. Interact. 2008, 173:179-186.
    • (2008) Chem. Biol. Interact. , vol.173 , pp. 179-186
    • Zamule, S.M.1    Strom, S.C.2    Omiecinski, C.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.