A ubiquitin-binding CUE domain in presenilin-1 enables interaction with K63-linked polyubiquitin chains

FEBS Letters

Volumn 589, Issue 9, 2015, Pages 1001-1008

  Duggan, Stephen P ^a   Yan, Run ^a   McCarthy, Justin V ^a  

^a UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

CUE domain; Presenilin; Signaling; Ubiquitin; Secretase

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA-PROTEIN (1-42); AMYLOID PRECURSOR PROTEIN; LYSINE; PEPTIDE FRAGMENT; POLYUBIQUITIN; PRESENILIN 1; PROTEIN BINDING; SECRETASE; UBIQUITIN;

AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CELL CULTURE; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; MOLECULAR GENETICS; MOUSE; MUTATION; PROTEIN DEGRADATION; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

AMINO ACID SEQUENCE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BINDING SITES; BLOTTING, WESTERN; CELLS, CULTURED; HEK293 CELLS; HUMANS; LYSINE; MICE; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDE FRAGMENTS; POLYUBIQUITIN; PRESENILIN-1; PROTEIN BINDING; PROTEOLYSIS; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; UBIQUITIN;

EID: 84930984937     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2015.03.008     Document Type: Article

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