The insulin-like growth factor 1 (IGF-1) receptor is a substrate for γ-secretase-mediated intramembrane proteolysis

Biochemical and Biophysical Research Communications

Volumn 358, Issue 4, 2007, Pages 1136-1141

  McElroy, Brian ^a   Powell, James C ^a   McCarthy, Justin V ^a  

^a UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

Secretase; Insulin like growth factor 1 (IGF 1) receptor; Presenilin; Regulated intramembrane proteolysis

Indexed keywords

GAMMA SECRETASE; GAMMA SECRETASE INHIBITOR; METALLOPROTEINASE; PHORBOL 13 ACETATE 12 MYRISTATE; SOMATOMEDIN C RECEPTOR; TYROSINE KINASE RECEPTOR;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SUBSTRATE; FRAGMENTATION REACTION; HUMAN; HUMAN CELL; INTRACELLULAR MEMBRANE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; CELL LINE; CELL MEMBRANE; ENZYME ACTIVATION; HUMANS; KIDNEY; MICE; MICE, KNOCKOUT; PEPTIDE HYDROLASES; PRESENILINS; RECEPTOR, IGF TYPE 1; SUBSTRATE SPECIFICITY;

EID: 34249664257     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.05.062     Document Type: Article

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