ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling

Nature Communications

Volumn 6, Issue , 2015, Pages

  Goossens, Steven ^a,b   Radaelli, Enrico ^c,d   Blanchet, Odile ^e,f   Durinck, Kaat ^g   Van Der Meulen, Joni ^g   Peirs, Sofie ^g   Taghon, Tom ^a   Tremblay, Cedric S ^b   Costa, Magdaline ^b   Ghahremani, Morvarid Farhang ^a   De Medts, Jelle ^a   Bartunkova, Sonia ^a   Haigh, Katharina ^a,b   Schwab, Claire ^h   Farla, Natalie ^a   Pieters, Tim ^a,g   Matthijssens, Filip ^g   Van Roy, Nadine ^g   Best, J Adam ⁱ   Deswarte, Kim ^a   Bogaert, Pieter ^a   Carmichael, Catherine ^b   Rickard, Adam ^b   Suryani, Santi ^j   Bracken, Lauryn S ^j   Alserihi, Raed ^k   Canté Barrett, Kirsten ^l   Haenebalcke, Lieven ^a   Clappier, Emmanuelle ^e,f   Rondou, Pieter ^g   Slowicka, Karolina ^a   Huylebroeck, Danny ^d,m   Goldrath, Ananda W ⁱ   Janzen, Viktor ⁿ   McCormack, Matthew P ^k   Lock, Richard B ^j   Curtis, David J ^b   Harrison, Christine ^h   Berx, Geert ^a   Speleman, Frank ^f   Meijerink, Jules P P ^l   Soulier, Jean ^e,f   Van Vlierberghe, Pieter ^g   Haigh, Jody J ^a,b   more..

^a GHENT UNIVERSITY   (Belgium)

^b MONASH UNIVERSITY   (Australia)

^c UNIVERSITY OF MILAN   (Italy)

^d UNIVERSITY OF LEUVEN   (Belgium)

^e UNIVERSITÉ PARIS DIDEROT   (France)

^f ANGERS UNIVERSITY HOSPITAL   (France)

^g GHENT UNIVERSITY HOSPITAL   (Belgium)

^h NEWCASTLE UNIVERSITY   (United Kingdom)

ⁱ UNIVERSITY OF CALIFORNIA   (United States)

^j UNIVERSITY OF NEW SOUTH WALES   (Australia)

^k UNIVERSITY OF MELBOURNE   (Australia)

^l SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^m ERASMUS MEDICAL CENTER   (Netherlands)

ⁿ UNIVERSITY OF BONN   (Germany)

more..

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 7 RECEPTOR; JANUS KINASE; STAT PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ZEB2; UNCLASSIFIED DRUG; HOMEODOMAIN PROTEIN; LUCIFERASE; REPRESSOR PROTEIN; ZFHX1B PROTEIN, MOUSE;

CELLS AND CELL COMPONENTS; GENE EXPRESSION; IMMUNE SYSTEM; METABOLISM; TUMOR;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL EXPERIMENT; ARTICLE; CARCINOGENESIS; CELL MATURATION; CELL SURVIVAL; CHROMOSOME BAND; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; DOWN REGULATION; EARLY CANCER; FEMALE; GENE EXPRESSION; IMMUNOPHENOTYPING; MALE; MOUSE; NONHUMAN; ONCOGENE; PROMOTER REGION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TRANSCRIPTION INITIATION; UPREGULATION; ANIMAL; CHROMATIN IMMUNOPRECIPITATION; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; HISTOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; KAPLAN MEIER METHOD; KARYOTYPING; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; T CELL LEUKEMIA; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CHROMATIN IMMUNOPRECIPITATION; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTOLOGICAL TECHNIQUES; HOMEODOMAIN PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; JANUS KINASES; KAPLAN-MEIER ESTIMATE; KARYOTYPING; LEUKEMIA, T-CELL; LUCIFERASES; MICE; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, INTERLEUKIN-7; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; STAT TRANSCRIPTION FACTORS;

EID: 84930970649     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms6794     Document Type: Article

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