Ascorbate and deferoxamine administration after chlorine exposure decrease mortality and lung injury in mice

American Journal of Respiratory Cell and Molecular Biology

Volumn 45, Issue 2, 2011, Pages 386-392

  Zarogiannis, Sotirios G ^a,b   Jurkuvenaite, Asta ^a,b   Fernandez, Solana ^a   Doran, Stephen F ^a   Yadav, Amit K ^a,b   Squadrito, Giuseppe L ^b   Postlethwait, Edward M ^b   Bowen, Larry ^c   Matalon, Sadis ^a,b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c SOUTHERN RESEARCH INSTITUTE   (United States)

Author keywords

Acute lung injury; Aerosols; Antioxidants; Oxidative stress; Survival

Indexed keywords

ASCORBIC ACID; CHLORINE; DEFEROXAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CAPILLARY PERMEABILITY; CELL COUNT; CONTROLLED STUDY; DRUG EFFICACY; DRUG TISSUE LEVEL; EPITHELIUM CELL; LIPID PEROXIDATION; LUNG INJURY; LUNG LAVAGE; MALE; MORTALITY; MOUSE; NEUTROPHIL COUNT; NONHUMAN; OXIDATIVE STRESS; PARTICLE SIZE; PNEUMONIA; RESPIRATORY EPITHELIUM; SURVIVAL RATE;

ACUTE LUNG INJURY; ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; CHEMICAL WARFARE AGENTS; CHLORINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEFEROXAMINE; INHALATION EXPOSURE; INJECTIONS, INTRAMUSCULAR; LIPID PEROXIDATION; MALE; MICE; MICE, INBRED C57BL; PNEUMONIA; SIDEROPHORES; SURVIVAL RATE;

ANIMALIA; MUS;

EID: 79955401356     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2010-0432OC     Document Type: Article

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