Post-exposure antioxidant treatment in rats decreases airway hyperplasia and hyperreactivity due to chlorine inhalation

American Journal of Respiratory Cell and Molecular Biology

Volumn 46, Issue 5, 2012, Pages 599-606

  Fanucchi, Michelle V ^a   Bracher, Andreas ^b,d   Doran, Stephen F ^a,b   Squadrito, Giuseppe L ^a   Fernandez, Solana ^a,b   Postlethwait, Edward M ^a   Bowen, Larry ^c   Matalon, Sadis ^a,b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c SOUTHERN RESEARCH INSTITUTE   (United States)

^d Universitatsklinik fur Dermatologie   (Austria)

Author keywords

Aerosol; Ascorbate; Deferoxamine; Epithelial injury; Epithelial repair; Mucosubstances

Indexed keywords

ASCORBIC ACID; CHLORINE; DEFEROXAMINE MESYLATE; GLUTATHIONE; SODIUM CHLORIDE;

AEROSOL; AIRWAY HYPERPLASIA; AIRWAY RESISTANCE; AMBIENT AIR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHUS HYPERREACTIVITY; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; DRUG MECHANISM; DRUG SAFETY; EXPOSURE; HYPERPLASIA; LUNG INJURY; MALE; MUCUS; NONHUMAN; RAT;

ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; BRONCHI; BRONCHIAL PROVOCATION TESTS; CHLORINE; GLUTATHIONE; HYPERPLASIA; INHALATION EXPOSURE; LUNG; MALE; RATS; RATS, SPRAGUE-DAWLEY; TRACHEA;

RATTUS;

EID: 84860534291     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2011-0196OC     Document Type: Article

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