메뉴 건너뛰기




Volumn 89, Issue 13, 2015, Pages 6575-6584

HIV blocks interferon induction in human dendritic cells and macrophages by dysregulation of TBK1

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; BINDING PROTEIN; INTERFERON; LYSINE; PATTERN RECOGNITION RECEPTOR; PHOSPHOTRANSFERASE; TANK BINDING KINASE 1; UNCLASSIFIED DRUG; VIF PROTEIN; VPR PROTEIN; PROTEIN SERINE THREONINE KINASE; TBK1 PROTEIN, HUMAN; VIF PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; VPR PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84930922500     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00889-15     Document Type: Article
Times cited : (74)

References (61)
  • 5
    • 77955884322 scopus 로고    scopus 로고
    • Within 1 h, HIV-1 uses viral synapses to enter efficiently the inner, but not outer, foreskin mucosa and engages Langerhans-T cell conjugates
    • Ganor Y, Zhou Z, Tudor D, Schmitt A, Vacher-Lavenu MC, Gibault L, Thiounn N, Tomasini J, Wolf JP, Bomsel M. 2010. Within 1 h, HIV-1 uses viral synapses to enter efficiently the inner, but not outer, foreskin mucosa and engages Langerhans-T cell conjugates. Mucosal Immunol 3:506-522. http://dx.doi.org/10.1038/mi.2010.32.
    • (2010) Mucosal Immunol , vol.3 , pp. 506-522
    • Ganor, Y.1    Zhou, Z.2    Tudor, D.3    Schmitt, A.4    Vacher-Lavenu, M.C.5    Gibault, L.6    Thiounn, N.7    Tomasini, J.8    Wolf, J.P.9    Bomsel, M.10
  • 6
    • 84877338763 scopus 로고    scopus 로고
    • R5 HIV-1 envelope attracts dendritic cells to cross the human intestinal epithelium and sample luminal virions via engagement of the CCR5
    • Cavarelli M, Foglieni C, Rescigno M, Scarlatti G. 2013. R5 HIV-1 envelope attracts dendritic cells to cross the human intestinal epithelium and sample luminal virions via engagement of the CCR5. EMBO Mol Med 5:776-794. http://dx.doi.org/10.1002/emmm.201202232.
    • (2013) EMBO Mol Med , vol.5 , pp. 776-794
    • Cavarelli, M.1    Foglieni, C.2    Rescigno, M.3    Scarlatti, G.4
  • 7
    • 84877324067 scopus 로고    scopus 로고
    • Initial HIV mucosal infection and dendritic cells
    • Cunningham AL, Harman A, Nasr N. 2013. Initial HIV mucosal infection and dendritic cells. EMBO Mol Med 5:658-660. http://dx.doi.org/10.1002/emmm.201202763.
    • (2013) EMBO Mol Med , vol.5 , pp. 658-660
    • Cunningham, A.L.1    Harman, A.2    Nasr, N.3
  • 12
    • 84897836190 scopus 로고    scopus 로고
    • Mechanisms underlying the inhibition of interferon signaling by viruses
    • Devasthanam AS. 2014. Mechanisms underlying the inhibition of interferon signaling by viruses. Virulence 5:270 -277. http://dx.doi.org/10.4161/viru.27902.
    • (2014) Virulence , vol.5 , pp. 270 -277
    • Devasthanam, A.S.1
  • 13
    • 79956300649 scopus 로고    scopus 로고
    • Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
    • Kawai T, Akira S. 2011. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 34:637-650. http://dx.doi.org/10.1016/j.immuni.2011.05.006.
    • (2011) Immunity , vol.34 , pp. 637-650
    • Kawai, T.1    Akira, S.2
  • 14
    • 84893637182 scopus 로고    scopus 로고
    • STING-dependent cytosolic DNA sensing pathways
    • Barber GN. 2014. STING-dependent cytosolic DNA sensing pathways. Trends Immunol 35:88-93. http://dx.doi.org/10.1016/j.it.2013.10.010.
    • (2014) Trends Immunol , vol.35 , pp. 88-93
    • Barber, G.N.1
  • 16
    • 67650230347 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome coronavirusMprotein inhibits type I interferon production by impeding the formation of TRAF3.TANK.TBK1/IKKepsilon complex
    • Siu KL, Kok KH, Ng MH, Poon VK, Yuen KY, Zheng BJ, Jin DY. 2009. Severe acute respiratory syndrome coronavirusMprotein inhibits type I interferon production by impeding the formation of TRAF3.TANK.TBK1/IKKepsilon complex. J Biol Chem 284:16202-16209. http://dx.doi.org/10.1074/jbc.M109.008227.
    • (2009) J Biol Chem , vol.284 , pp. 16202-16209
    • Siu, K.L.1    Kok, K.H.2    Ng, M.H.3    Poon, V.K.4    Yuen, K.Y.5    Zheng, B.J.6    Jin, D.Y.7
  • 17
    • 84869208689 scopus 로고    scopus 로고
    • Hepatitis C virus NS2 protease inhibits host cell antiviral response by inhibiting IKKepsilon and TBK1 functions
    • Kaukinen P, Sillanpaa M, Nousiainen L, Melen K, Julkunen I. 2013. Hepatitis C virus NS2 protease inhibits host cell antiviral response by inhibiting IKKepsilon and TBK1 functions. J Med Virol 85:71-82. http://dx.doi.org/10.1002/jmv.23442.
    • (2013) J Med Virol , vol.85 , pp. 71-82
    • Kaukinen, P.1    Sillanpaa, M.2    Nousiainen, L.3    Melen, K.4    Julkunen, I.5
  • 18
    • 77955290279 scopus 로고    scopus 로고
    • Hepatitis B virus polymerase inhibits RIG-I- and Toll-like receptor 3-mediated beta interferon induction in human hepatocytes through interference with interferon regulatory factor 3 activation and dampening of the interaction between TBK1/IKKepsilon and DDX3
    • Yu S, Chen J, Wu M, Chen H, Kato N, Yuan Z. 2010. Hepatitis B virus polymerase inhibits RIG-I- and Toll-like receptor 3-mediated beta interferon induction in human hepatocytes through interference with interferon regulatory factor 3 activation and dampening of the interaction between TBK1/IKKepsilon and DDX3. J Gen Virol 91:2080-2090. http://dx.doi.org/10.1099/vir.0.020552-0.
    • (2010) J Gen Virol , vol.91 , pp. 2080-2090
    • Yu, S.1    Chen, J.2    Wu, M.3    Chen, H.4    Kato, N.5    Yuan, Z.6
  • 19
    • 84899584959 scopus 로고    scopus 로고
    • SARS coronavirus papain-like protease inhibits the type I interferon signaling pathway through interaction with the STING-TRAF3-TBK1 complex
    • Chen X, Yang X, Zheng Y, Yang Y, Xing Y, Chen Z. 2014. SARS coronavirus papain-like protease inhibits the type I interferon signaling pathway through interaction with the STING-TRAF3-TBK1 complex. Protein Cell 5:369-381. http://dx.doi.org/10.1007/s13238-014-0026-3.
    • (2014) Protein Cell , vol.5 , pp. 369-381
    • Chen, X.1    Yang, X.2    Zheng, Y.3    Yang, Y.4    Xing, Y.5    Chen, Z.6
  • 20
    • 19944370132 scopus 로고    scopus 로고
    • Identification of the rabies virus alpha/beta interferon antagonist: phosphoprotein P interferes with phosphorylation of interferon regulatory factor 3
    • Brzozka K, Finke S, Conzelmann KK. 2005. Identification of the rabies virus alpha/beta interferon antagonist: phosphoprotein P interferes with phosphorylation of interferon regulatory factor 3. J Virol 79:7673-7681. http://dx.doi.org/10.1128/JVI.79.12.7673-7681.2005.
    • (2005) J Virol , vol.79 , pp. 7673-7681
    • Brzozka, K.1    Finke, S.2    Conzelmann, K.K.3
  • 21
    • 84866740475 scopus 로고    scopus 로고
    • Evolutionary conflicts between viruses and restriction factors shape immunity
    • Duggal NK, Emerman M. 2012. Evolutionary conflicts between viruses and restriction factors shape immunity. Nat Rev Immunol 12:687-695. http://dx.doi.org/10.1038/nri3295.
    • (2012) Nat Rev Immunol , vol.12 , pp. 687-695
    • Duggal, N.K.1    Emerman, M.2
  • 22
    • 84865069404 scopus 로고    scopus 로고
    • Vpu-deficient HIV strains stimulate innate immune signaling responses in target cells
    • Doehle BP, Chang K, Fleming L, McNevin J, Hladik F, McElrath MJ, Gale M, Jr. 2012. Vpu-deficient HIV strains stimulate innate immune signaling responses in target cells. J Virol 86:8499-8506. http://dx.doi.org/10.1128/JVI.00424-12.
    • (2012) J Virol , vol.86 , pp. 8499-8506
    • Doehle, B.P.1    Chang, K.2    Fleming, L.3    McNevin, J.4    Hladik, F.5    McElrath, M.J.6    Gale, M.7
  • 23
    • 84865106370 scopus 로고    scopus 로고
    • Vpu mediates depletion of interferon regulatory factor 3 during HIV infection by a lysosome-dependent mechanism
    • Doehle BP, Chang K, Rustagi A, McNevin J, McElrath MJ, Gale M, Jr. 2012. Vpu mediates depletion of interferon regulatory factor 3 during HIV infection by a lysosome-dependent mechanism. J Virol 86:8367-8374. http://dx.doi.org/10.1128/JVI.00423-12.
    • (2012) J Virol , vol.86 , pp. 8367-8374
    • Doehle, B.P.1    Chang, K.2    Rustagi, A.3    McNevin, J.4    McElrath, M.J.5    Gale, M.6
  • 24
    • 70349748582 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 mediates global disruption of innate antiviral signaling and immune defenses within infected cells
    • Doehle BP, Hladik F, McNevin JP, McElrath MJ, Gale M, Jr. 2009. Human immunodeficiency virus type 1 mediates global disruption of innate antiviral signaling and immune defenses within infected cells. J Virol 83:10395-10405. http://dx.doi.org/10.1128/JVI.00849-09.
    • (2009) J Virol , vol.83 , pp. 10395-10405
    • Doehle, B.P.1    Hladik, F.2    McNevin, J.P.3    McElrath, M.J.4    Gale, M.5
  • 25
    • 40649114040 scopus 로고    scopus 로고
    • HIV-1 accessory proteins VPR and Vif modulate antiviral response by targeting IRF-3 for degradation
    • Okumura A, Alce T, Lubyova B, Ezelle H, Strebel K, Pitha PM. 2008. HIV-1 accessory proteins VPR and Vif modulate antiviral response by targeting IRF-3 for degradation. Virology 373:85-97. http://dx.doi.org/10.1016/j.virol.2007.10.042.
    • (2008) Virology , vol.373 , pp. 85-97
    • Okumura, A.1    Alce, T.2    Lubyova, B.3    Ezelle, H.4    Strebel, K.5    Pitha, P.M.6
  • 26
    • 84878553328 scopus 로고    scopus 로고
    • HIV-1 Vpu does not degrade interferon regulatory factor 3
    • Hotter D, Kirchhoff F, Sauter D. 2013. HIV-1 Vpu does not degrade interferon regulatory factor 3. J Virol 87:7160-7165. http://dx.doi.org/10.1128/JVI.00526-13.
    • (2013) J Virol , vol.87 , pp. 7160-7165
    • Hotter, D.1    Kirchhoff, F.2    Sauter, D.3
  • 31
    • 34347259525 scopus 로고    scopus 로고
    • IL-28 and IL-29: newcomers to the interferon family
    • Uze G, Monneron D. 2007. IL-28 and IL-29: newcomers to the interferon family. Biochimie 89:729 -734. http://dx.doi.org/10.1016/j .biochi.2007.01.008.
    • (2007) Biochimie , vol.89 , pp. 729 -734
    • Uze, G.1    Monneron, D.2
  • 32
    • 84876059224 scopus 로고    scopus 로고
    • Recent insights into the complexity of Tank-binding kinase 1 signaling networks: the emerging role of cellular localization in the activation and substrate specificity of TBK1
    • Helgason E, Phung QT, Dueber EC. 2013. Recent insights into the complexity of Tank-binding kinase 1 signaling networks: the emerging role of cellular localization in the activation and substrate specificity of TBK1. FEBS Lett 587:1230-1237. http://dx.doi.org/10.1016/j.febslet.2013.01.059.
    • (2013) FEBS Lett , vol.587 , pp. 1230-1237
    • Helgason, E.1    Phung, Q.T.2    Dueber, E.C.3
  • 35
    • 79952837091 scopus 로고    scopus 로고
    • The leader proteinase of foot-and-mouth disease virus negatively regulates the type I interferon pathway by acting as a viral deubiquitinase
    • Wang D, Fang L, Li P, Sun L, Fan J, Zhang Q, Luo R, Liu X, Li K, Chen H, Chen Z, Xiao S. 2011. The leader proteinase of foot-and-mouth disease virus negatively regulates the type I interferon pathway by acting as a viral deubiquitinase. J Virol 85:3758-3766. http://dx.doi.org/10.1128/JVI.02589-10.
    • (2011) J Virol , vol.85 , pp. 3758-3766
    • Wang, D.1    Fang, L.2    Li, P.3    Sun, L.4    Fan, J.5    Zhang, Q.6    Luo, R.7    Liu, X.8    Li, K.9    Chen, H.10    Chen, Z.11    Xiao, S.12
  • 36
    • 80055115107 scopus 로고    scopus 로고
    • Varicella-zoster virus immediate-early protein ORF61 abrogates the IRF3-mediated innate immune response through degradation of activated IRF3
    • Zhu H, Zheng C, Xing J, Wang S, Li S, Lin R, Mossman KL. 2011. Varicella-zoster virus immediate-early protein ORF61 abrogates the IRF3-mediated innate immune response through degradation of activated IRF3. J Virol 85:11079-11089. http://dx.doi.org/10.1128/JVI.05098-11.
    • (2011) J Virol , vol.85 , pp. 11079-11089
    • Zhu, H.1    Zheng, C.2    Xing, J.3    Wang, S.4    Li, S.5    Lin, R.6    Mossman, K.L.7
  • 37
    • 59849118148 scopus 로고    scopus 로고
    • Interferons: signaling, antiviral and viral evasion
    • Bonjardim CA, Ferreira PC, Kroon EG. 2009. Interferons: signaling, antiviral and viral evasion. Immunol Lett 122:1-11. http://dx.doi.org/10.1016/j.imlet.2008.11.002.
    • (2009) Immunol Lett , vol.122 , pp. 1-11
    • Bonjardim, C.A.1    Ferreira, P.C.2    Kroon, E.G.3
  • 38
    • 84866166950 scopus 로고    scopus 로고
    • ORF45 of Kaposi's sarcoma-associated herpesvirus inhibits phosphorylation of interferon regulatory factor 7 by IKKepsilon and TBK1 as an alternative substrate
    • Liang Q, Fu B, Wu F, Li X, Yuan Y, Zhu F. 2012. ORF45 of Kaposi's sarcoma-associated herpesvirus inhibits phosphorylation of interferon regulatory factor 7 by IKKepsilon and TBK1 as an alternative substrate. J Virol 86:10162-10172. http://dx.doi.org/10.1128/JVI.05224-11.
    • (2012) J Virol , vol.86 , pp. 10162-10172
    • Liang, Q.1    Fu, B.2    Wu, F.3    Li, X.4    Yuan, Y.5    Zhu, F.6
  • 40
    • 84871649863 scopus 로고    scopus 로고
    • The pivotal role of TBK1 in inflammatory responses mediated by macrophages
    • Yu T, Yi YS, Yang Y, Oh J, Jeong D, Cho JY. 2012. The pivotal role of TBK1 in inflammatory responses mediated by macrophages. Mediators Inflamm 2012:979105. http://dx.doi.org/10.1155/2012/979105.
    • (2012) Mediators Inflamm , vol.2012 , pp. 979105
    • Yu, T.1    Yi, Y.S.2    Yang, Y.3    Oh, J.4    Jeong, D.5    Cho, J.Y.6
  • 43
    • 80053589982 scopus 로고    scopus 로고
    • IFN-lambdas
    • Kotenko SV. 2011. IFN-lambdas. Curr Opin Immunol 23:583-590. http://dx.doi.org/10.1016/j.coi.2011.07.007.
    • (2011) Curr Opin Immunol , vol.23 , pp. 583-590
    • Kotenko, S.V.1
  • 45
    • 79952823854 scopus 로고    scopus 로고
    • Possible role of phosphoinositide-3-kinase in Mx1 protein translation and antiviral activity of interferon-omega-stimulated HeLa cells
    • Seo Y, Kim M, Choi M, Kim S, Park K, Oh I, Chung S, Suh H, Hong S, Park S. 2011. Possible role of phosphoinositide-3-kinase in Mx1 protein translation and antiviral activity of interferon-omega-stimulated HeLa cells. Pharmacology 87:224-231. http://dx.doi.org/10.1159/000324536.
    • (2011) Pharmacology , vol.87 , pp. 224-231
    • Seo, Y.1    Kim, M.2    Choi, M.3    Kim, S.4    Park, K.5    Oh, I.6    Chung, S.7    Suh, H.8    Hong, S.9    Park, S.10
  • 48
    • 55549102621 scopus 로고    scopus 로고
    • PLP2, a potent deubiquitinase from murine hepatitis virus, strongly inhibits cellular type I interferon production
    • Zheng D, Chen G, Guo B, Cheng G, Tang H. 2008. PLP2, a potent deubiquitinase from murine hepatitis virus, strongly inhibits cellular type I interferon production. Cell Res 18:1105-1113. http://dx.doi.org/10.1038/cr.2008.294.
    • (2008) Cell Res , vol.18 , pp. 1105-1113
    • Zheng, D.1    Chen, G.2    Guo, B.3    Cheng, G.4    Tang, H.5
  • 49
    • 84904891938 scopus 로고    scopus 로고
    • Porcine epidemic diarrhea virus nucleocapsid protein antagonizes beta interferon production by sequestering the interaction between IRF3 and TBK1
    • Ding Z, Fang L, Jing H, Zeng S, Wang D, Liu L, Zhang H, Luo R, Chen H, Xiao S. 2014. Porcine epidemic diarrhea virus nucleocapsid protein antagonizes beta interferon production by sequestering the interaction between IRF3 and TBK1. J Virol 88:8936-8945. http://dx.doi.org/10.1128/JVI.00700-14.
    • (2014) J Virol , vol.88 , pp. 8936-8945
    • Ding, Z.1    Fang, L.2    Jing, H.3    Zeng, S.4    Wang, D.5    Liu, L.6    Zhang, H.7    Luo, R.8    Chen, H.9    Xiao, S.10
  • 50
    • 63149113399 scopus 로고    scopus 로고
    • Ebola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1
    • Prins KC, Cardenas WB, Basler CF. 2009. Ebola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1. J Virol 83:3069-3077. http://dx.doi.org/10.1128/JVI .01875-08.
    • (2009) J Virol , vol.83 , pp. 3069-3077
    • Prins, K.C.1    Cardenas, W.B.2    Basler, C.F.3
  • 51
    • 77956497003 scopus 로고    scopus 로고
    • Acryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells
    • Manel N, Hogstad B, Wang Y, Levy DE, Unutmaz D, Littman DR. 2010. Acryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells. Nature 467:214-217. http://dx.doi.org/10.1038/nature09337.
    • (2010) Nature , vol.467 , pp. 214-217
    • Manel, N.1    Hogstad, B.2    Wang, Y.3    Levy, D.E.4    Unutmaz, D.5    Littman, D.R.6
  • 55
    • 84905369006 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells suppress HIV-1 replication but contribute to HIV-1 induced immunopathogenesis in humanized mice
    • Li G, Cheng M, Nunoya J, Cheng L, Guo H, Yu H, Liu YJ, Su L, Zhang L. 2014. Plasmacytoid dendritic cells suppress HIV-1 replication but contribute to HIV-1 induced immunopathogenesis in humanized mice. PLoS Pathog 10:e1004291. http://dx.doi.org/10.1371/journal.ppat.1004291.
    • (2014) PLoS Pathog , vol.10 , pp. e1004291
    • Li, G.1    Cheng, M.2    Nunoya, J.3    Cheng, L.4    Guo, H.5    Yu, H.6    Liu, Y.J.7    Su, L.8    Zhang, L.9
  • 57
    • 77950659445 scopus 로고    scopus 로고
    • The macrophage in HIV-1 infection: from activation to deactivation?
    • Herbein G, Varin A. 2010. The macrophage in HIV-1 infection: from activation to deactivation? Retrovirology 7:33. http://dx.doi.org/10.1186/1742-4690-7-33.
    • (2010) Retrovirology , vol.7 , pp. 33
    • Herbein, G.1    Varin, A.2
  • 59
    • 84919429177 scopus 로고    scopus 로고
    • Triggering TLR2, -3, -4, -5, and -8 reinforces the restrictive nature of M1- and M2-polarized macrophages to HIV
    • Schlaepfer E, Rochat MA, Duo L, Speck RF. 2014. Triggering TLR2, -3, -4, -5, and -8 reinforces the restrictive nature of M1- and M2-polarized macrophages to HIV. J Virol 88:9769-9781. http://dx.doi.org/10.1128/JVI.01053-14.
    • (2014) J Virol , vol.88 , pp. 9769-9781
    • Schlaepfer, E.1    Rochat, M.A.2    Duo, L.3    Speck, R.F.4
  • 60
    • 67650152516 scopus 로고    scopus 로고
    • M1 and M2a polarization of human monocyte-derived macrophages inhibits HIV-1 replication by distinct mechanisms
    • Cassol E, Cassetta L, Rizzi C, Alfano M, Poli G. 2009. M1 and M2a polarization of human monocyte-derived macrophages inhibits HIV-1 replication by distinct mechanisms. J Immunol 182:6237-6246. http://dx .doi.org/10.4049/jimmunol.0803447.
    • (2009) J Immunol , vol.182 , pp. 6237-6246
    • Cassol, E.1    Cassetta, L.2    Rizzi, C.3    Alfano, M.4    Poli, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.