Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 24, 2012, Pages 9378-9383

  Ma, Xiaolei ^a   Helgason, Elizabeth ^a   Phung, Qui T ^a   Quan, Clifford L ^a   Iyer, Rekha S ^a   Lee, Michelle W ^a   Bowman, Krista K ^a   Starovasnik, Melissa A ^a   Dueber, Erin C ^a  

^a GENENTECH INC   (United States)

Author keywords

Crystallography; Kinase activation

Indexed keywords

I KAPPA B KINASE INHIBITOR; TANK BINDING KINASE 1; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHOSPHORYLATION; CONFORMATIONAL TRANSITION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; HUMAN; INNATE IMMUNITY; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; TRANSAUTOPHOSPHORYLATION;

CATALYSIS; ENZYME ACTIVATION; HUMANS; MODELS, MOLECULAR; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN-SERINE-THREONINE KINASES;

EID: 84862233012     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1121552109     Document Type: Article

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