Characterization of cultured microglia that can be infected by HIV-1

Journal of NeuroVirology

Volumn 6, Issue SUPPL. 1, 2000, Pages

  Albright, Andrew V ^a   Shieh, Joseph T C ^a   O'Connor, Michael J ^b   Gonzalez Scarano F ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Glia; HIV 1 infection; Microglia; Microglial activation

Indexed keywords

CD14 ANTIGEN; CD45 ANTIGEN; CD68 ANTIGEN; CYTOKINE; GLYCOPROTEIN P 15095;

CELL CULTURE; CELL STRUCTURE; CONFERENCE PAPER; CONTROLLED STUDY; CULTURE MEDIUM; GLIA CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTERMETHOD COMPARISON; MICROGLIA; PARENCHYMA; PLANT GROWTH; PRIORITY JOURNAL; SERUM; TEMPORAL LOBE; VIRUS REPLICATION;

ADULT; ANTIGENS, CD; ANTIGENS, CD14; ANTIGENS, CD45; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; CELLS, CULTURED; CULTURE MEDIA, SERUM-FREE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HIV-1; HUMANS; INTEGRIN ALPHAXBETA2; MACROPHAGES; MICROGLIA; MONOCYTES; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 0034075577     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (39)

1. Albright AV, Shieh JTC, Itoh T, Lee B, Pleasure D, O'Connor MJ, Doms RW, Gonzalez-Scarano F (1999). Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for HIV-1 Dementia isolates. J Virol 73: 205-213.
2. Albright AV, Strizki J, Harouse JM, Lavi E, O'Connor M, Gonzalez-Scarano F (1996). HIV-1 infection of cultured human adult oligodendrocytes. Virology 217: 211-219.
3. Bagasra O, Lavi E, Bobroski L, Tawadros R, Pestaner JP, Pomerantz RJ (1996). Cellular reservoirs of HIV-1 in the central nervous system of infected-individuals: identification by the combination of in situ PCR and immunohistochemistry. AIDS 10: 573-585.
4. Becher B, Antel JP (1996). Comparison of phenotypic and functional properties of immediately ex vivo and cultured human adult microglia. Glia 18: 1-10.
5. Brinkmann R, Schwinn A, Narayan O, Zink C, Kreth HW, Roggendorf W, Dorries R, Schwender S, Imrich H, ter Meulen V (1992). Human immunodeficiency virus infection in microglia: correlation between cells infected in the brain and cells cultured from infectious brain tissue. Ann Neurol 31: 361-365.
6. Brinkmann R, Schwinn A, Muller J, Stahl-Hennig C, Coulibaly C, Hunsmann G, Czub S, Rethwilm A, Dorries R, ter Meulen V (1993). In vitro and in vivo infection of rhesus monkey microglial cells by Simian immunodeficiency virus. Virology 195: 561-568.
7. Dick AD, Pell M, Brew BJ, Foulcher E, Sedgwick JD (1997). Direct ex vivo flow cytometric analysis of human microglial cell CD4 expression: examination of central nervous system biopsy specimens from HJIV-seropositive patients and patients with other neurological disease. AIDS 11: 1699-1708.
8. Dickson DW, Lee SC (1996). Microglia in HIV-related CNS neuropathology: an update. J Neuro-AIDS 1: 57-84.
9. Gabuzda DH, Ho DD, de la Monte SM, Hirsch MS, Rota TR, Sobel RA (1986). Immunohistochemical identification of HTLV-III antigen in brains of patients with AIDS. Ann Neurol 20: 289-295.
10. Gehrmann J, Matsumoto Y, Kreutzberg GW (1995). Microglia: intrinsic immuneffector cell of the brain. Brain Res Brain Res Rev 20: 269-287.
11. Graeber MB, Streit WJ, Kreutzberg GW (1989). Identity of ED2-positive perivascular cells in the rat brain. J Neurosci Res 22: 103-106.
12. Heidenreich S (1999). Monocyte CD14: a multifunctional receptor engaged in apoptosis from both sides. J Leukoc Biol 65: 737-743.
13. Hickey WF, Vass K, Lassmann H (1992). Bone marrow derived elements in the central nervous system: An immunohistochemical and ultrastuctural survey of rat chimeras. J Neuropathol Exp Neurol 51: 246-256.
14. Jordan CA, Watkins BA, Kufta C, Dubois-Dalcq M (1991). Infection of brain microglial cells by human immunodeficiency virus type 1 is CD4 dependent. J Virol 65: 736-742.
15. Lackner AA (1996). Neuroinvasion and the neuropathogenesis of HIV infection (Editorial). Brain Pathol 6: 12-14.
16. Lackner AA, Smith MO, Munn RJ, Martfeld DJ, Gardner MB, Marx PA, Dandekar S (1991). Localization of SIV in the CNS of Rhesus Monkeys. Am J Pathol 139: 609-621.
17. Lane JH, Sasseville VG, Smith MO, Vogel P, Pauley DR, Heyes MP, Lackner AA (1996a). Neuroinvasion by Simian Immunodeficiency Virus coincides with increased numbers of perivascular macrophages/microglia and intrathecal immune activation. J Neurovirol 2: 423-432.
18. Lane JH, Tarantal AF, Pauley D, Marthas M, Miller CJ, Lackner AA (1996b). Localization of simian immunodeficiency virus nucleic acid and antigen in brains of fetal macaques inoculated in utero. Am J Pathol 149: 1097-1104.
19. Lassmann H, Schmied M, Vass K, Hickey WF (1993). Bone marrow derived elements and resident microglia in brain inflammation. Glia 7: 19-24.
20. Lee B, Sharron M, Montaner LJ, Weissman D, Doms RW (1999). Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages. Proc Natl Acad Sci 96: 5215-5220.
21. Popovic M, Gartner S (1987). Isolation of HIV-1 from monocytes but not T lymphocytes (letter). Lancet 17: 916.
22. Rezaie P, Male D (1999). Colonisation of the developing human brain and spinal cord by microglia: a review. Microsc Res Tech 15: 359-382.
23. Rich EA, Chen ISY, Zack JA, Leonard ML, O'Brien WA (1992). Increased susceptibility of differentiated mononuclear phagocytes to productive infection with human immunodeficiency virus-1 (HIV-1). J Clin Invest 89: 176-183.
24. Saito Y, Sharer LR, Epstein LG, Michaels J, Mintz M, Louder M, Golding K, Cvetkovich TA, Blumberg BM (1994). Overexpression of nef as a marker for restricted HIV-1 infection of astrocytes in postmortem pediatric central nervous tissues. Neurology 44: 474-481.
25. Shahabuddin M, Volsky B, Kim H, Sakai K, Volsky DJ (1992). Regulated expression of human immunodeficiency virus type 1 in human glial cells: Induction of dormant virus. Pathobiology 60: 195-205.
26. Sharpless NE, O'Brien WA, Verdin E, Kufta CV, Chen ISY, Dubois-Dalcq M (1992). Human immunodeficiency virus type 1 tropism for brain microglial cells is determined by a region of the env glycoprotein that also controls macrophage tropism. J Virol 66: 2588-2593.
27. Shieh JTC, Albright AV, Sharron M, Gartner S, Strizki J, Doms RW, Gonzalez-Scarano F (1998). Chemokine receptor utilization by HIV-1 isolates that replicate in microglia. J Virol 72: 4243-4249.
28. Sonza S, Maerz A, Deacon N, Meanger J, Mills J, Growe S (1996). Human immunodefiency virus type 1 replication is blocked prior to reverse transcription and integration in freshly isolated peripheral blood monocytes. J Virol 70: 3863-3869.
29. Streit WJ, Graeber MB (1993). Heterogeneity of microglial and perivascular cell populations: insights gained from the facial nucleus paradigm. Glia 7: 68-74.
30. Strizki JM, Albright AV, Sheng H, O'Connor M, Perrin L, Gonzalez-Scarano F (1996). Infection of primary human microglia and monocyte-derived macrophages with human immunodeficiency virus type 1 isolates: evidence of differential tropism. J Virol 70: 7654-7662.
31. Theele DP, Streit WJ (1993). A chronicle of microglial ontogeny. Glia 7: 5-8.
32. Ulvestad E, Williams K, Mork S, Antel J, Nyland H (1994). Phenotypic differences between human monocytes/macrophages and microglial cells studied in situ and in vitro. J Neuropath Exp Neurol 53: 492-501.
33. Vodicka MA, Goh WC, Wu LI, Rogel ME, Bartz SR, Schweickart VL, Raport CJ, Emerman M (1997). Indicator cell lines for detection of primary strains of human and simian immunodeficiency viruses. Virology 233: 193-198.
34. Watkins BA, Dorn HH, Kelly WB, Armstrong RC, Potts BJ, Michaels F, Kufta CV, Dubois-Dalq M (1990). Specific tropism of HIV-1 for microglial cells in primary human brain cultures. Science 249: 549-552.
35. Wiley CA, Schrier RD, Nelson JA, Lampert PW, Oldstone MBA (1986). Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients. Proc Natl Acad Sci USA 83: 7089-7093.
36. Williams K, Bar-Or A, Ulvestad E, Olivier A, Antel JP, Wee Yong M (1992). Biology of adult human microglia in culture: comparisons with peripheral blood monocytes and astrocytes. J Neuropath Exp Neurol 51: 538-549.
37. Williams KC, Hickey WF (1996). Traffic of lymphocytes into the CNS during inflammation and HIV infection. J Neuro-AIDS 1: 31-55.
38. Yong VW, Antel JP (1992). Culture of glial cells from human brain biopsies. In: Protocols for Neural Cell Culture. Fedoroff S, Richardson A, (Eds.), Humana Press: Totowa, New Jersey, pp 81-96.
39. Ziegler-Heitbrock HW, Ulevitch RJ (1993). CD14: cell surface receptor and differentiation marker. Immunol Today 14: 121-125.