SARS coronavirus papain-like protease inhibits the type I interferon signaling pathway through interaction with the STING-TRAF3-TBK1 complex

Protein and Cell

Volumn 5, Issue 5, 2014, Pages 369-381

  Chen, Xiaojuan ^a   Yang, Xingxing ^a,b   Zheng, Yang ^a   Yang, Yudong ^a   Xing, Yaling ^a   Chen, Zhongbin ^a,b  

^a BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^b ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

deubiquitinase; interferon; papain like protease; SARS coronavirus; STING TRAF3 TBK1 complex

Indexed keywords

INTERFERON; PAPAIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; I KAPPA B KINASE; INTERFERON REGULATORY FACTOR 3; MEMBRANE PROTEIN; MPYS PROTEIN, HUMAN; PEPTIDE HYDROLASE; PROTEIN BINDING; PROTEIN SERINE THREONINE KINASE; TBK1 PROTEIN, HUMAN; TRAF3 PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; INNATE IMMUNITY; LUCIFERASE ASSAY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SARS CORONAVIRUS; SIGNAL TRANSDUCTION; UBIQUITINATION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DIMERIZATION; ENZYMOLOGY; GENETICS; HEK293 CELL LINE; METABOLISM; PHOSPHORYLATION; PROTEIN TERTIARY STRUCTURE;

SARS CORONAVIRUS;

DIMERIZATION; HEK293 CELLS; HUMANS; I-KAPPA B KINASE; INTERFERON REGULATORY FACTOR-3; INTERFERON TYPE I; MEMBRANE PROTEINS; PAPAIN; PEPTIDE HYDROLASES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; SARS VIRUS; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 3; UBIQUITINATION;

EID: 84899584959     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-014-0026-3     Document Type: Article

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