Impairment of hepatic nuclear factor-4α binding to the stim1 promoter contributes to high glucose-induced upregulation of stim1 expression in glomerular mesangial cells

American Journal of Physiology - Renal Physiology

Volumn 308, Issue 10, 2015, Pages F1135-F1145

  Wang, Yanxia ^a   Chaudhari, Sarika ^a   Ren, Yuezhong ^b   Ma, Rong ^a  

^a UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

^b THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Diabetic nephropathy; Hepatic nuclear factor 4 ; High glucose; Mesangial cells; Storeoperated Ca2+ entry; Stromal interacting molecule 1

Indexed keywords

CALCIUM ION; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL 1; COLLAGEN TYPE 4; FIBRONECTIN; GLUCOSE; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; SMALL INTERFERING RNA; CALCIUM; CALCIUM CHANNEL; HEPATOCYTE NUCLEAR FACTOR 4; HNF4A PROTEIN, HUMAN; MEMBRANE PROTEIN; ORAI1 PROTEIN, HUMAN; PROTEIN BINDING; STIM1 PROTEIN, HUMAN; TUMOR PROTEIN;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CALCIUM TRANSPORT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; GENE; GENE EXPRESSION; GENE OVEREXPRESSION; GENE REPRESSION; GENE SILENCING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MESANGIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; STIM1 GENE; UPREGULATION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CYTOLOGY; DIABETIC NEPHROPATHY; DOSE RESPONSE; DRUG EFFECTS; HEK293 CELL LINE; IN VITRO STUDY; METABOLISM; PHYSIOLOGY;

CALCIUM; CALCIUM CHANNELS; CELLS, CULTURED; COLLAGEN TYPE IV; DIABETIC NEPHROPATHIES; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBRONECTINS; GLUCOSE; HEK293 CELLS; HEPATOCYTE NUCLEAR FACTOR 4; HUMANS; IN VITRO TECHNIQUES; MEMBRANE PROTEINS; MESANGIAL CELLS; NEOPLASM PROTEINS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RNA, SMALL INTERFERING; UP-REGULATION;

EID: 84930856215     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00563.2014     Document Type: Article

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