Mediation of angiotensin II-induced Ca2+ signaling by polycystin 2 in glomerular mesangial cells

American Journal of Physiology - Renal Physiology

Volumn 294, Issue 4, 2008, Pages

  Du, Juan ^a,b   Ding, Min ^a   Sours Brothers, Sherry ^a   Graham, Sarabeth ^a   Ma, Rong ^a  

^a UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

^b ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Calcium channel

Indexed keywords

ANGIOTENSIN II; POLYCYSTIN 2; TRANSIENT RECEPTOR POTENTIAL CHANNEL 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL 4; CALCIUM; POLYCYSTIC KIDNEY DISEASE 2 PROTEIN; POLYCYSTIN;

ANIMAL TISSUE; ARTICLE; CALCIUM SIGNALING; CHANNEL GATING; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; MALE; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT; WESTERN BLOTTING; BIOTINYLATION; CELL CULTURE; CYTOLOGY; DRUG EFFECT; FLUORESCENCE MICROSCOPY; IMMUNOBLOTTING; MESANGIUM; METABOLISM; PATCH CLAMP; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANGIOTENSIN II; BIOTINYLATION; CALCIUM; CELLS, CULTURED; GLOMERULAR MESANGIUM; HUMANS; IMMUNOBLOTTING; MICROSCOPY, FLUORESCENCE; PATCH-CLAMP TECHNIQUES; SIGNAL TRANSDUCTION; TRPP CATION CHANNELS;

EID: 44949158946     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00606.2007     Document Type: Article

References (56)

1. Chang MY, Parker E, Ibrahim S, Shortland JR, Nahas ME, Haylor JL, Ong AC. Haploinsufficiency of Pkd2 is associated with increased tubular cell proliferation and interstitial fibrosis in two murine Pkd2 models. Nephrol Dial Transplant 21: 2078-2084, 2006.
2. Chapman A, Johnson A, Koehny W. Glomerular hyperfiltration: an early manifestation of autosomal dominant polycystic kidney disease. Kidney Int 35: 203A, 1989.
3. Delmas P, Nauli SM, Li XG, Coste B, Osorio N, Crest M, Brown DA, Zhou J. Gating of the polycystin ion channel signaling complex in neurons and kidney cells. FASEB J 18: 740-742, 2004.
4. Du J, Sours-Brothers S, Coleman R, Ding M, Graham S, Kong D, Ma R. TRPC1 channel is involved in contractile function of glomerular mesangial cells. J Am Soc Nephrol 18: 1437-1445, 2007.
5. Foggensteiner L, Bevan AP, Thomas R, Coleman N, Boulter C, Bradley J, Ibraghimov-Beskrovnaya O, Klinger K, Sandford R. Cellular and subcellular distribution of polycystin-2, the protein product of the PKD2 gene. J Am Soc Nephrol 11: 814-827, 2000.
6. Gabow PA. Autosomal dominant polycystic kidney disease. Am J Kidney Dis 22: 511-512, 1993.
7. 2+-permeable nonselective cation channel. Proc Natl Acad Sci USA 98: 1182-1187, 2001.
8. 2+ signaling in glomerular mesangial cells. Am J Physiol Renal Physiol 293: F1381-F1390, 2007.
9. Grantham JJ. The etiology, pathogenesis, and treatment of autosomal dominant polycystic kidney disease: recent advances. Am J Kidney Dis 28: 788-803, 1996.
10. Hanaoka K, Qian F, Boletta A, Bhunia AK, Piontek K, Tsiokas L, Sukhatme VP, Guggino WB, Germino GG. Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents. Nature 408: 990-994, 2000.
11. Hebert LA, Greene T, Levey A, Falkenhain ME, Klahr S. High urine volume and low urine osmolarity are risk factors for faster progression of renal disease. Am J Kidney Dis 41: 962-971, 2003.
12. Kasner SE, Ganz MB. Regulation of intracellular potassium in mesangial cells: a fluorescence analysis using the dye PBFI. Am J Physiol Renal Fluid Electrolyte Physiol 262: F462-F467, 1992.
13. Keith DS, Torres VE, Johnson CM, Holley KE. Effect of sodium chloride, enalapril, and losartan on the development of polycystic kidney disease in Han:SPRD rats. Am J Kidney Dis 24: 491-498, 1994.
14. i reduction increases cellular proliferation and apoptosis in vascular smooth muscle cells. Circ Res 96: 873-880, 2005.
15. Köttgen M, Benzing T, Simmen T, Tauber R, Buchholz B, Feliciangeli S, Huber TB, Schermer B, Kramer-Zucker A, Höpker K, Simmen KC, Tschucke CC, Sandford R, Kim E, Thomas G, Walz G. Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation. EMBO J 24: 705-716, 2005.
16. Koulen P, Cai YQ, Geng L, Maeda Y, Nishimura S, Witzgall R, Ehrlich BE, Somlo S. Polycystin-2 is an intracellular calcium release channel. Nat Cell Biol 4: 191-197, 2002.
17. Ling BN, Seal EE, Eaton DC. Regulation of mesangial cell ion channel by insulin and angiotensin II-possible role in diabetic glomerular hyperfiltration. J Clin Invest 92: 2141-2151, 1993.
18. 2+-permeable cation channel in renal epithelia. Mol Cell Biol 23: 2600-2607, 2003.
19. Ma R, Li WP, Rundle D, Kong J, Akbarali HI, Tsiokas L. PKD2 functions as an epidermal growth factor-activated plasma membrane channel. Mol Cell Biol 25: 8285-8298, 2005.
20. Ma R, Pluznick JL, Sansom SC. Ion channels in mesangial cells: function, malfunction, or fiction. Physiology 20: 102-111, 2005.
21. 2+ channels in human glomerular mesangial cells. Am J Physiol Renal Physiol 278: F954-F961, 2000.
22. Markowitz GS, Cai Y, Li L, Wu G, Ward LC, Somlo S, D'Agati V. Polycystin-2 expression is developmentally regulated. Am J Physiol Renal Physiol 277: F17-F25, 1999.
23. Matsunaga H, Yamashita N, Miyajima Y, Okuda T, Chang H, Ogata E, Kurokawa K. Ion channel activities of cultured rat mesangial cells. Am J Physiol Renal Fluid Electrolyte Physiol 261: F808-F814, 1991.
24. Menè P, Simonson MS, Dunn MJ. Physiology of mesangial cell. Physiol Rev 69: 1347-1424, 1989.
25. Michaud J, Russo P, Grignon A, Dallaire L, Bichet D, Rosenblat E, Lamothe E, Lambert M. Autosomal dominant polycystic kidney diseases in the fetus. Am J Med Genet 51: 240-246, 1994.
26. Mochizuki T, Wu G, Hayashi T, Xenophontos SL, Veldhuisen B, Saris JJ, Reynolds DM, Cai Y, Gabow PA, Pierides A, Kimberling WJ, Breuning MH, Deltas CC, Peters DJ, Somlo S. PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein. Science 272: 1339-1342, 1996.
27. Montell C, Birnbaumer L, Flockerzi V, Bindels R, Bruford EA, Caterina MJ, Clapham DE, Harteneck C, Heller S, Julius D, Kojima I, Mori Y, Penner R, Prawitt D, Scharenberg AM, Schultz G, Shimizu N, Zhu MX. A unified nomenclature for the superfamily of TRP cation channels. Mol Cell 9: 229-231, 2002.
28. Nauli SM, Alengha FJ, Luo Y, Williams E, Vassilev P, Li X, Elia AEH, Lu W, Brown EM, Quinn SJ, Ingber DE, Zhou J. Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nat Genet 33: 129-137, 2003.
29. Nauli SM, Rossetti S, Kolb RJ, Alenghat FJ, Consugar MB, Harris PC, Ingber DE, Loghman-Adham M, Zhou J. Loss of polycystin-1 in human cyst-lining epithelia leads to ciliary dysfunction. J Am Soc Nephrol 17: 1015-1025, 2005.
30. Nauli SM, Zhou J. Polycystins and mechanosensation in renal and nodal cilia. Bioessays 26: 844-856, 2004.
31. Newby LJ, Streets AJ, Zhao Y, Harris PC, Ward CJ, Ong ACM. Identification, characterization, and localization of a novel kidney polycystin-1-polycystin-2 complex. J Biol Chem 277: 20763-20773, 2002.
32. Omori S, Hida M, Fujita H, Takahashi H, Tanimura S, Kohno M, Awazu M. Extracellular signal-regulated kinase inhibition slows disease progression in mice with polycystic kidney disease. J Am Soc Nephrol 17: 1604-1614, 2006.
33. Ong ACM, Harris PC. Molecular pathogenesis of ADPKD: the polycystin complex gets complex. Kidney Int 67: 1234-1247, 2005.
34. Praetorius HA, Spring KR. Bending the MDCK cell primary cilium increases intracellular calcium. J Membr Biol 184: 71-79, 2001.
35. Pritchard L, Sloane-Stanley JA, Sharpe JA, Aspinwall R, Lu W, Buckle V, Strmecki L, Walker D, Ward CJ, Alpers CE, Zhou J, Wood WG, Harris PC. A human PKD1 transgene generates functional polycystin-1 in mice and is associated with a cystic phenotype. Hum Mol Genet 9: 2617-2627, 2000.
36. Qian Q, Hunter LW, Li M, Marin-Padilla M, Prakash YS, Somlo S, Harris PC, Torres VE, Sieck GC. Pkd2 haploinsufficiency alters intracellular calcium regulation in vascular smooth muscle cells. Hum Mol Genet 12: 1875-1880, 2003.
37. Qian Q, Li M, Cai Y, Ward CJ, Somlo S, Harris PC, Torres VE. Analysis of the polycystins in aortic vascular smooth muscle cells. J Am Soc Nephrol 14: 2280-2287, 2003.
38. Reeders ST, Zerres K, Gal A, Hogenkamp T, Propping P, Schidt W, Waldherr R, Dolata MM, Davies KE, Weatheral DJ. Prenatal diagnosis of autosomal dominant polycystic kidney disease with a DNA probe. Lancet 2: 6-8, 1986.
39. Reynolds DM. Aberrant splicing in the PKD2 gene as a cause of polycystic kidney disease. J Am Soc Nephrol 10: 2342-2351, 1999.
40. Rundle DR, Gorbsky G, Tsiokas L. PKD2 interacts and co-localizes with mDial1 to mitotic spindles of dividing cells. J Biol Chem 279: 29728-29739, 2004.
41. Siroky BJ, Ferguson WB, Fuson AL, Xie Y, Fintha A, Komlosi P, Yoder BK, Schwiebert EM, Guay-Woodford LM, Bell PD. Loss of primary cilia results in deregulated and unabated apical calcium entry in ARPKD collecting duct cells. Am J Physiol Renal Physiol 290: F1320-F1328, 2006.
42. Sours S, Du J, Chu S, Ding M, Zhou JX, Ma R. Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. Am J Physiol Renal Physiol 290: F1507-F1515, 2006.
43. Stockand JD, Sansom SC. Glomerular mesangial cells: electrophysiology and regulation of contraction. Physiol Rev 78: 723-744, 1998.
44. Streets AJ, Moon DJ, Kane ME, Obara T, Ong ACM. Identification of an N-terminal glycogen synthase kinase 3 phosphorylation site which regulates the functional localization of polycystin-2 in vivo and in vitro. Hum Mol Genet 15: 1465-1473, 2006.
45. Tanner GA, Tielker MA, Connors BA, Phillips CL, Tanner JA, Evan AP. Atubular glomeruli in a rat model of polycystic kidney disease. Kidney Int 62: 1947-1957, 2002.
46. Tsiokas L, Arnould T, Zhu C, Kim E, Walz G, Sukhatme VP. Specific association of the gene product of PKD2 with the TRPC1 channel. Proc Natl Acad Sci USA 96: 3934-3939, 1999.
47. Tsiokas L, Kim E, Arnould T, Sukhatme VP, Walz G. Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2. Proc Natl Acad Sci USA 94: 6965-6970, 1997.
48. 2+ homeostasis in polycystic kidney disease. Biochem Biophys Res Commun 282: 341-350, 2001.
49. Waldherr R, Zerres K, Gall A, Enders H. Polycystic kidney disease in the fetus. Lancet 2: 274-275, 1989.
50. 2+ channels in mouse mesangial cells. Am J Physiol Cell Physiol 287: C357-C364, 2004.
51. Weimbs T. Polycystic kidney disease and renal injury repair: common pathways, fluid flow, and the function of polycystin-1. Am J Physiol Renal Physiol 293: F1423-F1432, 2007.
52. Wilson PD. Polycystic kidney disease: new understanding in the pathogenesis. Int J Biochem Cell Biol 36: 1868-1873, 2004.
53. i in rabbit cortical collecting duct. Am J Physiol Renal Physiol 283: F437-F446, 2002.
54. Wongt H, Vivian L, Weiler G, Filler G. Patients with autosomal dominant polycystic kidney disease hyperfiltrate early in their disease. Am J Kidney Dis 43: 624-628, 2004.
55. Yoder BK, Mulroy S, Eustace H, Boucher C, Sandford R. Molecular pathogenesis of autosomal dominant polycystic kidney disease. Expert Rev Mol Med 8: 1-22, 2006.
56. Zeier M, Fehrenbach P, Geberth S. Renal histology in polycystic kidney disease with incipient and advanced renal failure. Kidney Int 42: 1259-1265, 1992.