Carbon monoxide negatively regulates NLRP3 inflammasome activation in macrophages

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 308, Issue 10, 2015, Pages L1058-L1067

  Jung, Sung Soo ^a,b   Moon, Jong Seok ^d,e   Xu, Jin Fu ^a,c   Ifedigbo, Emeka ^a   Ryter, Stefan W ^d,e   Choi, Augustine M K ^d,e   Nakahira, Kiichi ^d,e  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b Chungnam National University   (South Korea)

^c TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^d NEW YORK PRESBYTERIAN HOSPITAL   (United States)

^e WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Interleukin 18; Leucine rich containing family; Mitochondria; Nucleotide binding domain; Pyrin domain containing 3

Indexed keywords

ADENOSINE TRIPHOSPHATE; CARBON MONOXIDE; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); AIM2 PROTEIN, MOUSE; ANTIMETABOLITE; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; DNA BINDING PROTEIN; IL1B PROTEIN, MOUSE; LIPOPOLYSACCHARIDE;

ANIMAL CELL; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CYTOKINE RELEASE; CYTOKINE RESPONSE; CYTOSOL; FLOW CYTOMETRY; IMMUNE RESPONSE; INFLAMMATION; MACROPHAGE ACTIVATION; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; MITOCHONDRIAL RESPIRATION; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; CYTOLOGY; MACROPHAGE; METABOLISM; MITOCHONDRION;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIMETABOLITES; CARBON MONOXIDE; CARRIER PROTEINS; CASPASE 1; DNA-BINDING PROTEINS; INFLAMMASOMES; INTERLEUKIN-18; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MICE; MITOCHONDRIA;

EID: 84930848355     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00400.2014     Document Type: Article

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