Anti-dsDNA antibodies induce inflammation via endoplasmic reticulum stress in human mesangial cells

Journal of Translational Medicine

Volumn 13, Issue 1, 2015, Pages

  Zhang, Hui ^a   Zhao, Chunmei ^a,b   Wang, Shuang ^a   Huang, Yuefang ^a   Wang, Hongyue ^a   Zhao, Jijun ^a   Yang, Niansheng ^a  

^a THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

^b XINJIANG MEDICAL UNIVERSITY   (China)

Author keywords

Anti dsDNA antibodies; Endoplasmic reticulum stress; Human mesangial cell; Inflammation

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ACTIVATING TRANSCRIPTION FACTOR 6; DOUBLE STRANDED DNA ANTIBODY; DOUBLE STRANDED RNA ACTIVATED PROTEIN KINASE LIKE ENDOPLASMIC RETICULUM KINASE; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INITIATION FACTOR 2ALPHA; INOSITOL REQUIRING KINASE 1ALPHA; INTERLEUKIN 1BETA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN KINASE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANTINUCLEAR ANTIBODY; ATF6 PROTEIN, HUMAN; ERN1 PROTEIN, HUMAN; PERK KINASE; PROTEIN BINDING; PROTEIN KINASE R; PROTEIN SERINE THREONINE KINASE; RIBONUCLEASE;

ADULT; ANTIGEN BINDING; ARTICLE; CELL NUCLEUS; CELL STIMULATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INFLAMMATION; LUPUS ERYTHEMATOSUS NEPHRITIS; MALE; MESANGIUM CELL; MIDDLE AGED; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; RECEPTOR BLOCKING; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; YOUNG ADULT; ADOLESCENT; DEMOGRAPHY; DRUG EFFECTS; METABOLISM; PATHOLOGY;

ACTIVATING TRANSCRIPTION FACTOR 6; ADOLESCENT; ADULT; ANTIBODIES, ANTINUCLEAR; DEMOGRAPHY; EIF-2 KINASE; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; FEMALE; HUMANS; INFLAMMATION; MALE; MESANGIAL CELLS; MIDDLE AGED; NF-KAPPA B; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; UP-REGULATION; YOUNG ADULT;

EID: 84930667149     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/s12967-015-0536-7     Document Type: Article

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