Hyperhomocysteinemia and function of the endoplasmic reticulum

Journal of Clinical Investigation

Volumn 107, Issue 10, 2001, Pages 1221-1222

  Ron, David ^a,b  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HOMOCYSTEINE;

ATHEROSCLEROSIS; CHOLESTEROL METABOLISM; ENDOPLASMIC RETICULUM; ENDOTHELIUM CELL; GENE MUTATION; HUMAN; HYPERHOMOCYSTEINEMIA; NONHUMAN; NOTE; OXIDATIVE STRESS; PRIORITY JOURNAL; THROMBOSIS;

EID: 0035011430     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI13092     Document Type: Note

References (20)

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7. Characterization of the stress-inducing effects of homocysteine
8. Homocysteine-induced changes in mRNA levels of genes coding or cytoplasmic- and endoplasmic reticulum-resident stress proteins in neuronal cell cultures
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11. Tripartite management of unfolded proteins in the endoplasmic reticulum
12. The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum
13. Dynamic interaction of BiP and the ER stress transducers in the unfolded protein response
14. Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model
15. The ER-overload response: Activation of NF-kappa B
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17. Inhibition of thrombomodulin surface expression and protein C activation by the thrombogenic agent homocysteine
18. Homocysteine inhibits von Willebrand factor processing and secretion by preventing transport from the endoplasmic reticulum
19. The unfolded protein response coordinates the production of endoplasmic reticulum protein and endoplasmic reticulum membrane
20. A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood