Quantitative global sensitivity analysis of a biologically based dose-response pregnancy model for the thyroid endocrine system

Frontiers in Pharmacology

Volumn 6, Issue MAY, 2015, Pages

  Lumen, Annie ^a   McNally, Kevin ^b   George, Nysia ^a   Fisher, Jeffrey W ^a   Loizou, George D ^b  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b HEALTH AND SAFETY LABORATORY   (United Kingdom)

Author keywords

BBDR; Global sensitivity analysis; Iodide; Modeling; PBPK; Pregnancy; Thyroid; Thyroid hormones

Indexed keywords

IODIDE; LIOTHYRONINE; THYROID HORMONE; THYROXINE;

ANALYTICAL PARAMETERS; ARTICLE; COMPUTER PROGRAM; GAUSSIAN PROCESS EMULATION; HUMAN; KIDNEY CLEARANCE; MORRIS SCREENING METHOD; PREGNANCY; QUANTITATIVE ANALYSIS; SCREENING; SENSITIVITY ANALYSIS; STATISTICAL ANALYSIS; THYROID FUNCTION; THYROID GLAND; UNCERTAINTY;

EID: 84930622935     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2015.00107     Document Type: Article

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